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Displaying 1-50 of 278 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Metabolic effects of hormonal contraceptivesRad M.Cohen A.F., prof. dr.Burggraaf J., prof. dr.Universiteit Leiden (UL)2015Venous thrombo-embolism Discriminant analysis Extended-regimen Contraceptive vaginal ring Oral contraceptives
The pursuit of user-friendly medicines : older people in the hot seatNotenboom K., PhDBouvy M.L., prof. dr.Leufkens H.G.M., prof. dr.Universiteit Utrecht (UU)2017Usability; User-friendly; Older patients; Elderly; Medicines; Medication use; Medication errors; Tablet breaking; Swallowing; Medication packaging;
Clinical pharmacology and therapeutic drug monitoring of first-line anti-tuberculosis drugsSturkenboom M.G.G., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis; Therapeutic drug monitoring;
Clinical pharmcology of ertapenem in the treatment of multidrug-resistant tuberculosisRijn S.P. vanAlffenaar J.W.C., prof. dr.Werf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Rijksuniversiteit Groningen (RUG)2019Tuberculosis; multidrug-resistant
Linezolid in multidrug-resistant tuberculosisBolhuis M.S., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2015Tuberculosis; Linezolid;
A quest to optimize the clinical pharmacology of tuberculosis and human immunodeficiency virus drug treatmentDaskapan A., PhDWerf T.S. van der, prof. dr.Alffenaar J.W.C., prof. dr.Stienstra Y., prof. dr.Rijksuniversiteit Groningen (RUG)2018Tuberculosis; Immunodeficiency virus drug treatment
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacologyBrake L.H.M. te, PHDBurger D.M., prof. dr.Russel F.G.M., prof. dr.Aarnoutse R.E., dr.Koenderink JB, dr. ir.Radboud Universiteit (RU)2016Tuberculosis; Clinical pharmacology;
Revisiting co-trimoxazole for the treatment of tuberculosisAlsaad N.S.I., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis;
Treatment response in childhood asthmaVijverberg S.J.H., PhDRaaijmakers J.A.M., prof. dr.Maitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2014Treatment outcomes; Children; Asthma;
Thiopurines in inflammatory bowel diseases: new perspectives to optimise safety and efficacyWong D.R., PhDMasclee A., prof. dr.Neef C., prof. dr.Hooymans P.M., dr.Engels L.G.J.B., dr.Universiteit Maastricht (UM)2015Thiopurines; Inflammatory bowel disease; Safety; Drug efficacy;
Monitoring patients using psychotropic drugsNederlof M., PhDEgberts A.C.G., prof. dr.Heerdink E.R., dr.Universiteit Utrecht (UU)2018Therapeutic drug monitoring; Biomarkers; Benefit-risk assessment; Psychotropic drugs; Psychiatry; Antidepressants; Antipsychotics
Tetrahydrocannabinol in the treatment of neuropsychiatric symptoms in dementiaElsen G. van den, PhDOlde Rikkert M., prof. dr.Verkes R., prof. dr.Marck M. van der, dr. ir.Kramers C., dr.Radboud Universiteit (RU)2016THC; geriatric medicine; pain; Dementia;
Targeting the ileo-colonic region in inflammatory bowel diseaseGareb BKosterink J.G.W., prof. dr.Frijlink H.W., prof. dr.Rijksuniversiteit Groningen (RUG)2021Targeting the ileo-colonic region in inflammatory bowel disease
Statin treatment in type 2 diabetes patiëntsVries F.M. de, PhDHak E., prof. dr.Denig P., prof. dr.Postma M.J., prof. dr.Rijksuniversiteit Groningen (RUG)2016Statins; Diabetes mellitus;
Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetics Strougo A., PhDDanhof M., prof. dr.Freijer J., dr.Yassen A., dr.Universiteit Leiden (UL)2015Special-population; Model-based; PK-model; Paediatrics; Children; Hepatic and renal impairment; Semi-physiological; Population approach; PBPK;
Solid dispersions in oncology: a solution to solubility-limited oral drug absorptionSawicki E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2017Solid dispersions; Pharmacokinetics; Spray drying; Freeze drying; Docetaxel; Paclitaxel; Elacridar;
Investigations of skin inflammation with a novel dermatology toolbox for early phase clinical drug developmentKolk T. van der, drBurggraaf J., prof. dr.Rissmann R, prof.dr.Universiteit Leiden (UL)2021Skin inflammation Dermatology toolbox Early phase clinical drug development Trial at home Inflammation models Skin microbiome Atopic dermatitis
Readmission to primary care : the role of community pharmacists post-dischargeEnsing H.T., PhDBouvy M.L., prof. dr.Koster E.S., PhDDooren A.A. van, dr.Universiteit Utrecht (UU)2017Safety; Care continuity; Discharge; Pharmacist home visit;
Communicating risk effectivelyPiening S., PhDHaaijer-Ruskamp F.M., prof. dr.Graeff P.A. de, prof. dr.Mol P.G.M., dr.Straus S.M.J.M., dr.Rijksuniversiteit Groningen (RUG)2013risk effectivity communicating risk drugs
The Renin-Angiotensin System in Hypertension and Diabetes: From Man to Rodent and BackRoksnoer L.C.W.Danser A.H.J., prof. dr.Zietse R., prof.dr.Hoorn E.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2016Renin-angiotensin system; Renal function; Hypertension; Diabetic kidney disease;
Renin-Synthesizing Cells and BeyondGoes Martini A., PhDDanser A.H.J., prof. dr.Neves F.A.R., prof. dr.Erasmus Universiteit Rotterdam (EUR)2017Renin-angiotensin system; Renal function;
New therapeutic targets in cardiovascular disease: focus on the renin-angiotensin system and lipid metabolismSun YDanser A.H.J., prof. dr.Lu X., PhDErasmus Universiteit Rotterdam (EUR)2020Renin-angiotensin system; lipid metabolism; Vascular reactivity; Pharmacology; Treatment options;
Salt, acid, and the renin-angiotensin system in chronic kidney diseaseBovée D.M., PhDHoorn E.J., prof. dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2021Renin-angiotensin system; Kidney; Pharmacology;
Renin-angiotensin system and genetic factors in aneurysms: a translational approachRiet L. te, PhDDanser A.H.J., prof. dr.Verhagen H.J.M., prof. dr.Essers J., dr.Rouwet E.V., dr.Erasmus Universiteit Rotterdam (EUR)2016Renin-angiotensin system; Genetics; Aneurysm
Novel protective approaches in ischemia-reperfusion injury. In vivo studies in animals and humansWever K.E., PhDRongen G.A., prof. dr.Masereeuw R., prof. dr.Warlé M.C., dr.Radboud Universiteit (RU)2012Renal, ischemia/reperfusion injury, remote ischemic preconditioning, Annexin A5, animal and human research
Myogenic constriction in renal failure; cause and therapyVavrinec P., PhDHenning R.H., prof. dr.Dokkum R.P.E. van, dr.Buikema J.H., dr.Rijksuniversiteit Groningen (RUG)2012renal failure myogenic constriction
Real-world treatment outcomes in metastatic lung cancer : from efficacy-effectiveness gap evaluation to informed clinical decision-makingWelle C.M. van derKlungel O.H., prof. dr.Groen H.J.M., prof. dr.Garde E.M.W. van de, dr.Schramel F.M.N.H., dr.Universiteit Utrecht (UU)2021Real-world data; Lung cancer; Treatment outcomes; Pharmacotherapy; Treatment patterns; Effectiveness; Survival; Pharmacoepidemiology; Web-based tool;
Pharmaceutical development, preclinical research and clinical application of the bone-targeting therapeutic radiopharmaceutical rhenium-188-HEDPLange R., PhDHendrikse N.H., prof. dr.Heine R. ter, dr.Bloemendal H.J., dr.Vrije Universiteit Amsterdam (VU)2017Radiopharmaceutics; Pharmaceutical development; Rhenium;
Off-target effects of RAAS-inhibition: importance on renal outcomes in patients with diabetesMiao Y., PhDGroen A.K., prof. dr.Zeeuw D. de, prof. dr.Rijksuniversiteit Groningen (RUG)2012RAAS-inhibition; Diabetes mellitus;
Appropriate prescribing for older peopleDrenth-van Maanen A.C., PhDEgberts A.C.G., prof. dr.Jansen P.A.F., dr.Marum R.J. van, prof. dr.Universiteit Utrecht (UU)2013Prescribing; Elderly; Polypharmacy; Transitional pharmaceutical care;
Prediction and prevention of chronic renal impairment in high-risk populations; type 2 diabetes, hypertension & lung transplantationHellemons M.E., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Bakker S.J.L., prof. dr.Rijksuniversiteit Groningen (RUG)2012prediction and prevention of chronic renal impairment type 2 diabetes lung transplantation
Preclinical molecular imgaging to study the biodistribution of antibody derivatives in oncology. Warnders J.F., PhDKosterink J.G.W., prof. dr.Vries E.G.E. de, prof. dr.Lub-de Hooge M.N., dr.Rijksuniversiteit Groningen (RUG)2018preclinical molecular imaging; oncology
Towards New Therapies for Preeclampsia: Restoring Vascular DysfunctionHitzerd AEReiss IKM, prof.dr.Danser A.H.J., prof. dr.Simons SHP, dr.Erasmus Universiteit Rotterdam (EUR)2020Pre-eclampsia; Treatment options; Pregnancy; Pharmacology;
Angiogenic imbalance in preeclampsia: pathogenic, diagnostic and prognostic implicationsSaleh L., PhDDanser A.H.J., prof. dr.Steegers E.A.P., prof. dr.Meiracker A.H. van den, dr.Visser W, Dr.Erasmus Universiteit Rotterdam (EUR)2018Pre-eclampsia; Pregnant women; Pregnancy; Renin-angiotensin system; Treatment options;
Preeclampsia, the renin-angiotensin-aldosterone system and beyondVerdonk K., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2015Pre-eclampsia; Antihypertensive drugs; Pharmacology; Primary care; Renin-angiotensin system;
Integrating biomarkers to predict renal and cardiovascular drug efficacy: PRE score applications from drug registration to personalized medicineSchievink B.H., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Rijksuniversiteit Groningen (RUG)2016PRE score; Risk markers; Chronic kidney disease; Personalized medicine;
Pharmacokinetics and/or pharmacodynamics of propofol, atracurium and cefazolin in morbidly obese patientsKralingen S. van, PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2011Population PK; Population PD; Obesity; Propofol; Cefazolin; Morbid obesity; Bariatric surgery; Atracurium;
The role of glomerular filtration and active tubular secretion in predicting renal clearance of drugs in children using population pharmacokinetic and physiology-based pharmacokinetic modeling approaches: unspinning the yarnCristea S., PhDKnibbe C.A.J., prof. dr.Allegaert K., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2021Population PK; Optimise drug dosing; Paediatric renal clearance; PBPK; Paediatrics; Renal clearance; Population pharmacokinetics; Physiologically based pharmacokinetics; Maturation; Active tubular secretion; Renal transporters;
Population pharmacokinetics of antibiotics to prevent group B streptococcal disease: from mother to neonateMuller A.E., dr.Danhof M., prof. dr.Steegers E.A.P., prof. dr.Dörr P.J., prof. dr.Mouton J.W., prof. dr.Universiteit Leiden (UL)2009Population PK; Antibiotics; Group B streptococcal infections; Pregnant women; Newborns; GBS (Group B streptococcus);
Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics: Tools of the tradeGoulooze S.C., PhDKnibbe C.A.J., prof. dr.Hankemeier T., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2020Population pharmacokinetics-pharmacodynamics; Repeated time-to-event modelling; Paediatric pharmacology; Pharmacometric methodology; Analgesia; Iatrogenic withdrawal; Postoperative pain; Item response theory (IRT); Analgesia and sedation; Real-world data; Paediatrics; Pharmacodynamics; Pharmacometrics;
Drug effects on the risk and prognosis of community-acquired pneumoniaGarde E.M.W. van de, dr.Leufkens H.G.M., prof. dr.Bosch J.M.M. van den, prof. dr.Souverein P.C., dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2007Pneumonia; Adults; Clinical outcomes; Prevention;
Thermopharmacology of anticonvulsive treatment after perinatal asphyxiaBroek M.P.H. van den, PhDEgberts A.C.G., prof. dr.Rademaker C.M.A., dr.Universiteit Utrecht (UU)2013PK-PD modelling; Newborns; Thermopharmacology; Convulsions;
Pharmacy Preparations: European quality standards and regulationScheepers H., drNeef C., prof. dr.Universiteit Maastricht (UM)2017Pharmacy policy;
Making better prescribers during a context-based pharmacotherapy learning programmeTichelaar J., dr.Vries Th.P.G.M. de, prof. dr. MDRichir M.C., MD PhDVrije Universiteit Amsterdam (VU)2016pharmacotherapy; pharmacotherapy education; context based learning; clinical pharmacology; prescribing
Learning in a student-run clinic: a new concept to improve medical education in pharmacotherapySchutte T., PhDAgtmael M.A. van, prof. dr.Richir M.C., MD PhDTichelaar J., dr.Vrije Universiteit Amsterdam (VU)2018Pharmacotherapy education; Student-run clinic; Medical education; Workplace learning; Undergraduate education;
The more complex renin-angiotensin system: new insights into an old systemGembardt F., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Renin-angiotensin system;
Quality of presribing in chronic kidney disease and type 2 diabetes. Smits K.P.J.Denig P., prof. dr.Muro E.P., PhDSidorenkov G., PhDRijksuniversiteit Groningen (RUG)2018Pharmacology; Prescribing; Chronic kidney disease;
Prediction and monitoring of chronic kidney diseaseBoele-Schutte E., PhDGansevoort R.T., prof. dr.Wolffenbuttel B.H.R., prof. dr.Lambers Heerspink H.J., prof. dr.Lutgers H.L., dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Prediction; Kidney disease;
First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and childrenBrussee J.M., PhDKnibbe C.A.J., prof. dr.Wildt S.N. de, prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2018Pharmacology; Pharmacokinetics; Paediatrics; Cytochrome P450; Drug metabolism; Midazolam; Population pharmacokinetics; Semi-PBPK modelling; CYP3A-mediated metabolism; First-pass metabolism;
Evaluation of renal end points in nephrology trials. Weldegiorgis MLambers Heerspink H.J., prof. dr.Zeeuw D. de, prof. dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Nephrology trials; renal endpoints
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