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Displaying 1-50 of 278 results.

Titel	Promovendus	Promotor 1	Promotor 2	Copromotor 1	Copromotor 2	Universiteit	Promotiejaar	Trefwoorden

Metabolic effects of hormonal contraceptives	Rad M.	Cohen A.F., prof. dr.	Burggraaf J., prof. dr.			Universiteit Leiden (UL)	2015	Venous thrombo-embolism Discriminant analysis Extended-regimen Contraceptive vaginal ring Oral contraceptives
The pursuit of user-friendly medicines : older people in the hot seat	Notenboom K., PhD	Bouvy M.L., prof. dr.	Leufkens H.G.M., prof. dr.			Universiteit Utrecht (UU)	2017	Usability; User-friendly; Older patients; Elderly; Medicines; Medication use; Medication errors; Tablet breaking; Swallowing; Medication packaging;
Clinical pharmacology and therapeutic drug monitoring of first-line anti-tuberculosis drugs	Sturkenboom M.G.G., PhD	Kosterink J.G.W., prof. dr.	Werf T.S. van der, prof. dr.	Uges D.R.A., prof. dr.	Alffenaar J.W.C., prof. dr.	Rijksuniversiteit Groningen (RUG)	2016	Tuberculosis; Therapeutic drug monitoring;
Clinical pharmcology of ertapenem in the treatment of multidrug-resistant tuberculosis	Rijn S.P. van	Alffenaar J.W.C., prof. dr.	Werf T.S. van der, prof. dr.	Kosterink J.G.W., prof. dr.		Rijksuniversiteit Groningen (RUG)	2019	Tuberculosis; multidrug-resistant
Linezolid in multidrug-resistant tuberculosis	Bolhuis M.S., PhD	Werf T.S. van der, prof. dr.	Kosterink J.G.W., prof. dr.	Uges D.R.A., prof. dr.	Alffenaar J.W.C., prof. dr.	Rijksuniversiteit Groningen (RUG)	2015	Tuberculosis; Linezolid;
A quest to optimize the clinical pharmacology of tuberculosis and human immunodeficiency virus drug treatment	Daskapan A., PhD	Werf T.S. van der, prof. dr.	Alffenaar J.W.C., prof. dr.	Stienstra Y., prof. dr.		Rijksuniversiteit Groningen (RUG)	2018	Tuberculosis; Immunodeficiency virus drug treatment
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacology	Brake L.H.M. te, PHD	Burger D.M., prof. dr.	Russel F.G.M., prof. dr.	Aarnoutse R.E., dr.	Koenderink JB, dr. ir.	Radboud Universiteit (RU)	2016	Tuberculosis; Clinical pharmacology;
Revisiting co-trimoxazole for the treatment of tuberculosis	Alsaad N.S.I., PhD	Kosterink J.G.W., prof. dr.	Werf T.S. van der, prof. dr.	Alffenaar J.W.C., prof. dr.		Rijksuniversiteit Groningen (RUG)	2016	Tuberculosis;
Treatment response in childhood asthma	Vijverberg S.J.H., PhD	Raaijmakers J.A.M., prof. dr.		Maitland-van der Zee A.H., prof. dr.		Universiteit Utrecht (UU)	2014	Treatment outcomes; Children; Asthma;
Thiopurines in inflammatory bowel diseases: new perspectives to optimise safety and efficacy	Wong D.R., PhD	Masclee A., prof. dr.	Neef C., prof. dr.	Hooymans P.M., dr.	Engels L.G.J.B., dr.	Universiteit Maastricht (UM)	2015	Thiopurines; Inflammatory bowel disease; Safety; Drug efficacy;
Monitoring patients using psychotropic drugs	Nederlof M., PhD	Egberts A.C.G., prof. dr.		Heerdink E.R., dr.		Universiteit Utrecht (UU)	2018	Therapeutic drug monitoring; Biomarkers; Benefit-risk assessment; Psychotropic drugs; Psychiatry; Antidepressants; Antipsychotics
Tetrahydrocannabinol in the treatment of neuropsychiatric symptoms in dementia	Elsen G. van den, PhD	Olde Rikkert M., prof. dr.	Verkes R., prof. dr.	Marck M. van der, dr. ir.	Kramers C., dr.	Radboud Universiteit (RU)	2016	THC; geriatric medicine; pain; Dementia;
Targeting the ileo-colonic region in inflammatory bowel disease	Gareb B	Kosterink J.G.W., prof. dr.	Frijlink H.W., prof. dr.			Rijksuniversiteit Groningen (RUG)	2021	Targeting the ileo-colonic region in inflammatory bowel disease
Statin treatment in type 2 diabetes patiënts	Vries F.M. de, PhD	Hak E., prof. dr.	Denig P., prof. dr.	Postma M.J., prof. dr.		Rijksuniversiteit Groningen (RUG)	2016	Statins; Diabetes mellitus;
Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetics	Strougo A., PhD	Danhof M., prof. dr.		Freijer J., dr.	Yassen A., dr.	Universiteit Leiden (UL)	2015	Special-population; Model-based; PK-model; Paediatrics; Children; Hepatic and renal impairment; Semi-physiological; Population approach; PBPK;
Solid dispersions in oncology: a solution to solubility-limited oral drug absorption	Sawicki E., PhD	Beijnen J.H., prof. dr.	Schellens J.H.M., prof. dr.	Nuijen B., dr.		Universiteit Utrecht (UU)	2017	Solid dispersions; Pharmacokinetics; Spray drying; Freeze drying; Docetaxel; Paclitaxel; Elacridar;
Investigations of skin inflammation with a novel dermatology toolbox for early phase clinical drug development	Kolk T. van der, dr	Burggraaf J., prof. dr.		Rissmann R, prof.dr.		Universiteit Leiden (UL)	2021	Skin inflammation Dermatology toolbox Early phase clinical drug development Trial at home Inflammation models Skin microbiome Atopic dermatitis
Readmission to primary care : the role of community pharmacists post-discharge	Ensing H.T., PhD	Bouvy M.L., prof. dr.		Koster E.S., PhD	Dooren A.A. van, dr.	Universiteit Utrecht (UU)	2017	Safety; Care continuity; Discharge; Pharmacist home visit;
Communicating risk effectively	Piening S., PhD	Haaijer-Ruskamp F.M., prof. dr.	Graeff P.A. de, prof. dr.	Mol P.G.M., dr.	Straus S.M.J.M., dr.	Rijksuniversiteit Groningen (RUG)	2013	risk effectivity communicating risk drugs
The Renin-Angiotensin System in Hypertension and Diabetes: From Man to Rodent and Back	Roksnoer L.C.W.	Danser A.H.J., prof. dr.	Zietse R., prof.dr.	Hoorn E.J., prof. dr.		Erasmus Universiteit Rotterdam (EUR)	2016	Renin-angiotensin system; Renal function; Hypertension; Diabetic kidney disease;
Renin-Synthesizing Cells and Beyond	Goes Martini A., PhD	Danser A.H.J., prof. dr.	Neves F.A.R., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2017	Renin-angiotensin system; Renal function;
New therapeutic targets in cardiovascular disease: focus on the renin-angiotensin system and lipid metabolism	Sun Y	Danser A.H.J., prof. dr.		Lu X., PhD		Erasmus Universiteit Rotterdam (EUR)	2020	Renin-angiotensin system; lipid metabolism; Vascular reactivity; Pharmacology; Treatment options;
Salt, acid, and the renin-angiotensin system in chronic kidney disease	Bovée D.M., PhD	Hoorn E.J., prof. dr.	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2021	Renin-angiotensin system; Kidney; Pharmacology;
Renin-angiotensin system and genetic factors in aneurysms: a translational approach	Riet L. te, PhD	Danser A.H.J., prof. dr.	Verhagen H.J.M., prof. dr.	Essers J., dr.	Rouwet E.V., dr.	Erasmus Universiteit Rotterdam (EUR)	2016	Renin-angiotensin system; Genetics; Aneurysm
Novel protective approaches in ischemia-reperfusion injury. In vivo studies in animals and humans	Wever K.E., PhD	Rongen G.A., prof. dr.		Masereeuw R., prof. dr.	Warlé M.C., dr.	Radboud Universiteit (RU)	2012	Renal, ischemia/reperfusion injury, remote ischemic preconditioning, Annexin A5, animal and human research
Myogenic constriction in renal failure; cause and therapy	Vavrinec P., PhD	Henning R.H., prof. dr.		Dokkum R.P.E. van, dr.	Buikema J.H., dr.	Rijksuniversiteit Groningen (RUG)	2012	renal failure myogenic constriction
Real-world treatment outcomes in metastatic lung cancer : from efficacy-effectiveness gap evaluation to informed clinical decision-making	Welle C.M. van der	Klungel O.H., prof. dr.	Groen H.J.M., prof. dr.	Garde E.M.W. van de, dr.	Schramel F.M.N.H., dr.	Universiteit Utrecht (UU)	2021	Real-world data; Lung cancer; Treatment outcomes; Pharmacotherapy; Treatment patterns; Effectiveness; Survival; Pharmacoepidemiology; Web-based tool;
Pharmaceutical development, preclinical research and clinical application of the bone-targeting therapeutic radiopharmaceutical rhenium-188-HEDP	Lange R., PhD	Hendrikse N.H., prof. dr.		Heine R. ter, dr.	Bloemendal H.J., dr.	Vrije Universiteit Amsterdam (VU)	2017	Radiopharmaceutics; Pharmaceutical development; Rhenium;
Off-target effects of RAAS-inhibition: importance on renal outcomes in patients with diabetes	Miao Y., PhD	Groen A.K., prof. dr.	Zeeuw D. de, prof. dr.			Rijksuniversiteit Groningen (RUG)	2012	RAAS-inhibition; Diabetes mellitus;
Appropriate prescribing for older people	Drenth-van Maanen A.C., PhD	Egberts A.C.G., prof. dr.		Jansen P.A.F., dr.	Marum R.J. van, prof. dr.	Universiteit Utrecht (UU)	2013	Prescribing; Elderly; Polypharmacy; Transitional pharmaceutical care;
Prediction and prevention of chronic renal impairment in high-risk populations; type 2 diabetes, hypertension & lung transplantation	Hellemons M.E., PhD	Zeeuw D. de, prof. dr.		Lambers Heerspink H.J., prof. dr.	Bakker S.J.L., prof. dr.	Rijksuniversiteit Groningen (RUG)	2012	prediction and prevention of chronic renal impairment type 2 diabetes lung transplantation
Preclinical molecular imgaging to study the biodistribution of antibody derivatives in oncology.	Warnders J.F., PhD	Kosterink J.G.W., prof. dr.	Vries E.G.E. de, prof. dr.	Lub-de Hooge M.N., dr.		Rijksuniversiteit Groningen (RUG)	2018	preclinical molecular imaging; oncology
Towards New Therapies for Preeclampsia: Restoring Vascular Dysfunction	Hitzerd AE	Reiss IKM, prof.dr.	Danser A.H.J., prof. dr.	Simons SHP, dr.		Erasmus Universiteit Rotterdam (EUR)	2020	Pre-eclampsia; Treatment options; Pregnancy; Pharmacology;
Angiogenic imbalance in preeclampsia: pathogenic, diagnostic and prognostic implications	Saleh L., PhD	Danser A.H.J., prof. dr.	Steegers E.A.P., prof. dr.	Meiracker A.H. van den, dr.	Visser W, Dr.	Erasmus Universiteit Rotterdam (EUR)	2018	Pre-eclampsia; Pregnant women; Pregnancy; Renin-angiotensin system; Treatment options;
Preeclampsia, the renin-angiotensin-aldosterone system and beyond	Verdonk K., PhD	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2015	Pre-eclampsia; Antihypertensive drugs; Pharmacology; Primary care; Renin-angiotensin system;
Integrating biomarkers to predict renal and cardiovascular drug efficacy: PRE score applications from drug registration to personalized medicine	Schievink B.H., PhD	Zeeuw D. de, prof. dr.	Lambers Heerspink H.J., prof. dr.			Rijksuniversiteit Groningen (RUG)	2016	PRE score; Risk markers; Chronic kidney disease; Personalized medicine;
Pharmacokinetics and/or pharmacodynamics of propofol, atracurium and cefazolin in morbidly obese patients	Kralingen S. van, PhD	Knibbe C.A.J., prof. dr.		Dongen H.P.A. van, dr.	Ramshorst B. van, dr.	Universiteit Leiden (UL)	2011	Population PK; Population PD; Obesity; Propofol; Cefazolin; Morbid obesity; Bariatric surgery; Atracurium;
The role of glomerular filtration and active tubular secretion in predicting renal clearance of drugs in children using population pharmacokinetic and physiology-based pharmacokinetic modeling approaches: unspinning the yarn	Cristea S., PhD	Knibbe C.A.J., prof. dr.	Allegaert K., prof. dr.	Krekels E.H.J., PhD		Universiteit Leiden (UL)	2021	Population PK; Optimise drug dosing; Paediatric renal clearance; PBPK; Paediatrics; Renal clearance; Population pharmacokinetics; Physiologically based pharmacokinetics; Maturation; Active tubular secretion; Renal transporters;
Population pharmacokinetics of antibiotics to prevent group B streptococcal disease: from mother to neonate	Muller A.E., dr.	Danhof M., prof. dr.	Steegers E.A.P., prof. dr.	Dörr P.J., prof. dr.	Mouton J.W., prof. dr.	Universiteit Leiden (UL)	2009	Population PK; Antibiotics; Group B streptococcal infections; Pregnant women; Newborns; GBS (Group B streptococcus);
Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics: Tools of the trade	Goulooze S.C., PhD	Knibbe C.A.J., prof. dr.	Hankemeier T., prof. dr.	Krekels E.H.J., PhD		Universiteit Leiden (UL)	2020	Population pharmacokinetics-pharmacodynamics; Repeated time-to-event modelling; Paediatric pharmacology; Pharmacometric methodology; Analgesia; Iatrogenic withdrawal; Postoperative pain; Item response theory (IRT); Analgesia and sedation; Real-world data; Paediatrics; Pharmacodynamics; Pharmacometrics;
Drug effects on the risk and prognosis of community-acquired pneumonia	Garde E.M.W. van de, dr.	Leufkens H.G.M., prof. dr.	Bosch J.M.M. van den, prof. dr.	Souverein P.C., dr.	Deneer V.H.M., dr.	Universiteit Utrecht (UU)	2007	Pneumonia; Adults; Clinical outcomes; Prevention;
Thermopharmacology of anticonvulsive treatment after perinatal asphyxia	Broek M.P.H. van den, PhD	Egberts A.C.G., prof. dr.		Rademaker C.M.A., dr.		Universiteit Utrecht (UU)	2013	PK-PD modelling; Newborns; Thermopharmacology; Convulsions;
Pharmacy Preparations: European quality standards and regulation	Scheepers H., dr	Neef C., prof. dr.				Universiteit Maastricht (UM)	2017	Pharmacy policy;
Making better prescribers during a context-based pharmacotherapy learning programme	Tichelaar J., dr.	Vries Th.P.G.M. de, prof. dr. MD		Richir M.C., MD PhD		Vrije Universiteit Amsterdam (VU)	2016	pharmacotherapy; pharmacotherapy education; context based learning; clinical pharmacology; prescribing
Learning in a student-run clinic: a new concept to improve medical education in pharmacotherapy	Schutte T., PhD	Agtmael M.A. van, prof. dr.		Richir M.C., MD PhD	Tichelaar J., dr.	Vrije Universiteit Amsterdam (VU)	2018	Pharmacotherapy education; Student-run clinic; Medical education; Workplace learning; Undergraduate education;
The more complex renin-angiotensin system: new insights into an old system	Gembardt F., PhD	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2011	Pharmacology; Renin-angiotensin system;
Quality of presribing in chronic kidney disease and type 2 diabetes.	Smits K.P.J.	Denig P., prof. dr.	Muro E.P., PhD	Sidorenkov G., PhD		Rijksuniversiteit Groningen (RUG)	2018	Pharmacology; Prescribing; Chronic kidney disease;
Prediction and monitoring of chronic kidney disease	Boele-Schutte E., PhD	Gansevoort R.T., prof. dr.	Wolffenbuttel B.H.R., prof. dr.	Lambers Heerspink H.J., prof. dr.	Lutgers H.L., dr.	Rijksuniversiteit Groningen (RUG)	2017	Pharmacology; Prediction; Kidney disease;
First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children	Brussee J.M., PhD	Knibbe C.A.J., prof. dr.	Wildt S.N. de, prof. dr.	Krekels E.H.J., PhD		Universiteit Leiden (UL)	2018	Pharmacology; Pharmacokinetics; Paediatrics; Cytochrome P450; Drug metabolism; Midazolam; Population pharmacokinetics; Semi-PBPK modelling; CYP3A-mediated metabolism; First-pass metabolism;
Evaluation of renal end points in nephrology trials.	Weldegiorgis M	Lambers Heerspink H.J., prof. dr.	Zeeuw D. de, prof. dr.			Rijksuniversiteit Groningen (RUG)	2017	Pharmacology; Nephrology trials; renal endpoints