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Displaying 51-100 of 278 results.

Titel	Promovendus	Promotor 1	Promotor 2	Copromotor 1	Copromotor 2	Universiteit	Promotiejaar	Trefwoorden

Optimizing protease inhibitor-based antiretroviral therapy for HIV-1 infected Thai adults and children	Lugt J. van der, dr.	Lange J.M.A., prof. dr.		Ananworanich J., dr.	Burger D.M., prof. dr.	Universiteit van Amsterdam (UvA)	2010	Antiretroviral; HIV; Pharmacokinetics; Clinical pharmacology; therapeutic drug monitoring
Human pharmacology of current and novel gaba(a)-ergic treatments for anxiety	Chen X., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Jacobs G.E., dr.		Universiteit Leiden (UL)	2017	Anxiety Human pharmacology GABA-ergic treatment
Development and use of biomarkers in clinical development of new therapies for chronic airway disease	Zuiker R.G.J.A	Burggraaf J., prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2016	Asthma COPD Biomarkers Allergen challenges Inflammation
Towards better treatment outcomes in childhood asthma	Koster E.S., PhD	Raaijmakers J.A.M., prof. dr.		Maitland-van der Zee A.H., prof. dr.		Universiteit Utrecht (UU)	2011	Asthma; Children; Treatment Outcomes; Epidemiology;
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation	Admiraal R., PhD	Knibbe C.A.J., prof. dr.		Boelens J.J., dr.	Bredius R.G.M., dr.	Universiteit Leiden (UL)	2017	ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy;
Future drugs in atherosclerotic cardiovascular disease	Poelgeest E.P van	Burggraaf J., prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2018	Atherosclerosis Systemic inflammation Hypercholesterolemia PCSK9 inhibitor TLR4 sinaling Acute kidney injury Endothelial dysfunction Human endotoxemia model Ex vivo LPS challenge test Invivo LPS challenge test
Implications of the cardiomyocyte stress response on protein homeostasis in atrial fibrillation	Wiersma M., PhD	Henning R.H., prof. dr.		Brundel B.J.J.M., dr.		Rijksuniversiteit Groningen (RUG)	2016	Atrial fibrillation;
Targeting proteostasis in atrial fibrillation	Zhang D., PhD	Henning R.H., prof. dr.		Brundel B.J.J.M., dr.		Rijksuniversiteit Groningen (RUG)	2015	Atrial fibrillation; Modelling-&-simulations;
Loss of proteostasis as a substrate for Atrial Fibrilation.	Meijering R.A.M., PhD	Henning R.H., prof. dr.		Brundel B.J.J.M., dr.		Rijksuniversiteit Groningen (RUG)	2014	Atrial fibrillation; Proteostasis;
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in children	Bellanti F., PhD	Danhof M., prof. dr.		Della Pasqua O.E., dr.		Universiteit Leiden (UL)	2015	Benefit-risk assessment; Paediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Benefits and risks for the individual : anticoagulation for patients with atrial fibrillation	Ham H.A. van den, PhD	Leufkens H.G.M., prof. dr.		Klungel O.H., prof. dr.	Staa T.J. van, prof. dr.	Universiteit Utrecht (UU)	2016	Benefit-risk balance; Atrial fibrillation; Oral anticoagulants; Observational studies; Individuals;
Pharmacovigilance of biologicals : dynamics in post-approval safety learning	Vermeer N.S., PhD	Leufkens H.G.M., prof. dr.	Egberts A.C.G., prof. dr.	Bruin M.L. de, prof. dr.	Straus S.M.J.M., dr.	Universiteit Utrecht (UU)	2015	Biologicals; Biosimilars; Pharmacovigilance; Adverse drug reactions; Regulatory science; Traceability; Risk management plan;
Monitoring patients using clozapine	Man W.H., PhD	Egberts A.C.G., prof. dr.	Solinge W.W. van, prof. dr.	Wilting I., dr.	Heerdink E.R., dr.	Universiteit Utrecht (UU)	2018	Biomarkers; Adherence; Monitoring; Sialorrhea; Inflammation; Glycopyrrolate; Schizophrenia; Antipsychotics; Pharmacovigilance;
Novel biomarker panels in diabetic kidney disease: predicting disease progression and response to therapy, and monitoring drug effect	Pena M.J., PhD	Zeeuw D. de, prof. dr.	Lambers Heerspink H.J., prof. dr.			Rijksuniversiteit Groningen (RUG)	2015	Biomarkers; Diabetes mellitus; Kidney;
Sticky & Dirty Proteins- or on the poorly characterised, peculiar, pharmacokinetic and immunostimulatory aspects of biopharmaceuticals	Reijers J.A.A.	Burggraaf J., prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2018	Biopharmaeuticals Biologics Clinical Pharmacology Pharmacokinetics Adverse immunostimulation Immunotoxicity Drug impurity Drug contamination Monoclonal antibody
Unravelling the link between diabetes, insulin treatment and breast cancer	Bronsveld H.K., PhD	Boer A. de, prof. dr.	Bruin M.L. de, prof. dr.	Schmidt M.K., dr. ir.		Universiteit Utrecht (UU)	2017	Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment;
New insights into the role of breast cancer resistance protein in endocrine and metabolic processes	Dankers A.C.A., PhD	Russel F.G.M., prof. dr.	Sweep C.G.J., prof. dr.	Masereeuw R., prof. dr.		Radboud Universiteit (RU)	2014	Cancer; Breast cancer;
Bioanalysis and clinical pharmacology of tamoxifen in breast cancer	Jager N.G.L., PhD	Beijnen J.H., prof. dr.	Schellens J.H.M., prof. dr.	Rosing H., dr.		Universiteit Utrecht (UU)	2014	Cancer; Clinical pharmacology;
Clinical pharmacology of genotype-directed anticancer therapy - Towards rational combination strategies	Geel R.M.J.M. van, PhD	Schellens J.H.M., prof. dr.	Beijnen J.H., prof. dr.	Huitema A.D.R., prof. dr.	Cats A., dr.	Universiteit Utrecht (UU)	2016	Cancer; Genetics; BRAF; Colorectal cancer; Combination therapy; p53-deficient ovarian cancer; AZD1775; Treatment individualization;
The role of pharmacogenetics in osteosarcoma	Hagleitner M.M., PhD	Hoogerbrugge P.M., prof. dr.	Guchelaar H.J., prof. dr.	Loo D.M.W.M. te, dr.	Coenen M.J.H., dr.	Radboud Universiteit (RU)	2015	Cancer; Osteosarcoma; Pharmacogenetics; Genetics; Chemotherapy;
Cardiovascular, renal and thyroid toxicity during angiogenesis inhibition: a translational approach	Kappers M.H.W., PhD	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2011	Cancer; Pharmacology; Antihypertensive drugs;
Novel approaches in clinical development of cannabinoid drugs	Klumpers L.E., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2014	Cannabinoids; THC; CB1 antagonists; Pharmacokinetics; Clinical pharmacology; Pharmacodynamics; Feeling high; PK-PD modelling; Resting state FMRI; Rimonabant;
The aging cardiovascular system: genetic and epigenetic determinants of vascular outcomes and cardiometabolic risk	Portilla Fernández E	Danser A.H.J., prof. dr.	Ikram MA, prof.dr.	Roks A.J.M., dr.	Dehghan A, dr.	Erasmus Universiteit Rotterdam (EUR)	2019	Cardiac aging; Cardiovascular disease; Genetics; Epidemiology; Epigenetics; Vascular reactivity; Pharmacology;
Techniques to improve neurological outcome after cardiac surgery	Kok W.F., PhD	Henning R.H., prof. dr.	Absalom A.R., prof. dr.	Scheeren T.W.L., prof. dr.		Rijksuniversiteit Groningen (RUG)	2017	Cardiac surgery; Clinical pharmacology; Neurological outcome;
Vascular reactivity in cardiopulmonary bypass	Samarska I., PhD	Henning R.H., prof. dr.	Struys M.M.R.F., prof. dr.	Buikema J.H., dr.	Epema A.H., dr.	Rijksuniversiteit Groningen (RUG)	2011	Cardiopulmonary bypass; Vascular reactivity;
Biomarkers as assessment of drug efficacy in cardiovascular disease	Smink P.A., PhD	Zeeuw D. de, prof. dr.		Lambers Heerspink H.J., prof. dr.	Bakker S.J.L., prof. dr.	Rijksuniversiteit Groningen (RUG)	2013	cardiovascular disease biomarkers drug efficacy
The role of aldosterone and aldosterone blockade in hypertension	Jansen P.M., PhD	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2013	Cardiovascular disease; Antihypertensive drugs; Pharmacology;
Multimodality ImAging of Cardiovascular Dysfunction: Risk factors, diagnostics and treatment options	Thiel B.S. van, PhD	Kanaar R., prof. dr.	Danser A.H.J., prof. dr.	Essers J., dr.	Pluijm I. van der, dr.	Erasmus Universiteit Rotterdam (EUR)	2017	Cardiovascular disease; Imaging; Aging; Risk factors; Diagnostics; Treatment options
Characterization of vascular 5-hydroxytryptamine, adrenergic and CGRP receptors in relation to migraine	Mehrotra S., dr.	Saxena P.R., prof. dr.		Danser A.H.J., prof. dr.	Maassen van den Brink A., dr.	Erasmus Universiteit Rotterdam (EUR)	2006	Cardiovascular disease; Pharmacology;
Vascular pharmacology of migraine and preeclampsia: Problems of the fair sex	Gupta S., dr.	Saxena P.R., prof. dr.		Danser A.H.J., prof. dr.	Maassen van den Brink A., dr.	Erasmus Universiteit Rotterdam (EUR)	2006	Cardiovascular disease; Pharmacology;
Vascular aging from DNA damage to protection	Ďurik M., PhD	Danser A.H.J., prof. dr.		Roks A.J.M., dr.		Erasmus Universiteit Rotterdam (EUR)	2012	Cardiovascular disease; Pharmacology;
Cardiac aldosterone: origin and effects	Chai W., dr.	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2005	Cardiovascular disease; Pharmacology;
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factors	Batenburg W.W., dr.	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2005	Cardiovascular disease; Pharmacology;
The (pro)renin receptor: moving away from prorenin?	Lu X., PhD	Danser A.H.J., prof. dr.		Meima M.E., dr.		Erasmus Universiteit Rotterdam (EUR)	2014	Cardiovascular disease; Pharmacology; Prorenin;
(Pro)renin revisited: new insights from studies in mast cells	Krop M., dr.	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2009	Cardiovascular disease; Pharmacology; Prorenin;
Unraveling the complexities of the renin-angiotensin system: from ACE to renin inhibition	Esch J.H.M. van, dr.	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2008	Cardiovascular disease; Pharmacology; Renin-angiotensin system;
Multimodality ImAging of Cardiovascular Dysfunction: Risk Factors, Diagnostics and Treatment Options	Thiel B.S. van, PhD	Kanaar R., prof. dr.	Danser A.H.J., prof. dr.	Essers J., dr.	Pluijm I. van der, dr.	Erasmus Universiteit Rotterdam (EUR)	2017	Cardiovascular disease; Risk factors; Treatment options;
Carotid artery contrast enhanced ultrasound	Kate G.L. ten, PhD	Sijbrands E.J.G., prof. dr.	Danser A.H.J., prof. dr.	Schinkel A.F.L., Dr.		Erasmus Universiteit Rotterdam (EUR)	2014	Cardiovascular disease; Vascular reactivity;
Endothelial dysfunction in cardiovascular disease	Heuvel M. van den, PhD	Duncker D.J.G.M., Prof.dr.	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2018	Cardiovascular disease; Vascular reactivity; Cholesterol;
DNA Damage-related Vascular Dysfunction: Pathways and Interventions	Bautista-Niño P.K., PhD	Danser A.H.J., prof. dr.	Franco Duran O.H., Prof.dr.	Roks A.J.M., dr.	Ghanbari M., dr.	Erasmus Universiteit Rotterdam (EUR)	2017	Cardiovascular disease; Vascular reactivity; DNA damage;
Experimental focal cerebral ischemia: optimalisation of models and therapeutic interventions	Shanbhag N.C., PhD	Henning R.H., prof. dr.	Schilling L., prof. dr.			Rijksuniversiteit Groningen (RUG)	2016	Cerebral ischemia;
COMPARE: Care in Oncolytic Medication surveillance:Pharmacovigilance, Acceptability, Risks and Events	Oijen B.P.C. van, dr.	Schouten H.C., prof. dr.		Kuy P.H.M. van der, dr.	Janknegt R., PharmD PhD	Universiteit Maastricht (UM)	2015	Chemotherapy; Clinical pharmacology; Pharmaceutical care;
Risk factors and treatment of paediatric chronic diseases - Type 1 diabetes, asthma and allergy	Ahmadizar F., PhD	Boer A. de, prof. dr.		Maitland-van der Zee A.H., prof. dr.		Universiteit Utrecht (UU)	2016	Children; Diabetes mellitus; Allergy
Comorbidities, complications and treatment of childhood obesity	Lentferink Y.E., PhD	Knibbe C.A.J., prof. dr.		Vorst M.M.J. van der, dr.		Universiteit Leiden (UL)	2019	Children; Obesity; Asthma; ADHD; Insulin resistance; Metformin; Cardiovascular diseases; Obese children; Arterial stiffness; Skin autofluorescence;
Optimization of electronic prescribing in pediatric patients	Maat B., PhD	Egberts A.C.G., prof. dr.	Vught A.J. van, prof. dr.	Rademaker C.M.A., dr.	Bollen C.W., dr.	Universiteit Utrecht (UU)	2014	Children; Paediatrics; Electronic prescribing;
Non-dispensing clinical pharmacists in general practice : training, implementation and clinical effects	Hazen A.C.M., PhD	Bouvy M.L., prof. dr.	Wit N.J. de, prof. dr.	Bont A.A. de, prof. dr.	Zwart D.L.M., dr.	Universiteit Utrecht (UU)	2018	Clinical pharmacist; General practice; Medication reviews; Polypharmacy; Hospitalization; Professional identity;
Integrated assessment of neurocognitive, neurophysiological and pain processing in early clinical drug development	Amerongen G. van, PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Groeneveld G.J., prof. dr.		Universiteit Leiden (UL)	2020	Clinical pharmacology Pharmacodynamics Pain Human pain models Cannabinoid GABA THC Multiple sclerosis (MS)
Drug-induced psychomimetic symptoms as a model for psychosis	Kleinloog-Fernández González H.D., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2014	Clinical Pharmacology Psychotic Disorders Clinical Trial Drug evaluation Biological Models
Making things easier: how to improve antiviral drug treatment for children	Bastiaans D.E.T., dr.	Burger D.M., prof. dr.				Radboud Universiteit (RU)	2016	Clinical pharmacology; Antiviral drug treatment;
Clinical pharmacology of novel anticancer drug formulations	Stuurman F.E, PhD	Schellens J.H.M., prof. dr.	Beijnen J.H., prof. dr.			Universiteit Utrecht (UU)	2013	Clinical pharmacology; Cancer;