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Displaying 51-100 of 270 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Clinical pharmacology of immuno-modulatory biotherapeutics : innovations in early drug developmentDillingh M.R., PhDBurggraaf J., prof. dr.Cohen A.F., prof. dr.Moerland M., dr.Universiteit Leiden (UL)2017Immuno-modulatory biotherapeutics; Drug development;
Clinical pharmacology of nevirapine in HIV-infected patients in TanzaniaMuro E.P., PhDBurger D.M., prof. dr.Dolmans W.M.V., prof. dr.Radboud Universiteit (RU)2014Clinical pharmacology; HIV; Pharmacokinetics; therapy drug monitoring
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studiesNijenhuis C.M., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Rosing H., dr.Universiteit Utrecht (UU)2016
Clinical pharmacology of novel anticancer drug formulationsStuurman F.E, PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Universiteit Utrecht (UU)2013Clinical pharmacology; Cancer;
Clinical pharmcology of ertapenem in the treatment of multidrug-resistant tuberculosisRijn S.P. vanAlffenaar J.W.C., prof. dr.Werf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Rijksuniversiteit Groningen (RUG)2019Tuberculosis; multidrug-resistant
Clinical risk management of drug-related hospital admissions: strategies for their identification, reduction and monitoringWarlé-van Herwaarden M., PhDSmet P.A.G.M. de, prof. dr.Sturkenboom M.C.J.M., prof. dr.Kramers C., dr.Herings R.M.C., dr.Radboud Universiteit (RU)2015Guideline adherence; medication safety; laboratory monitoring
Cognition in Huntington's disease : the influence of motor behaviour and time Hart E.P. 't, PhDRoos R.A.C., prof. dr.Universiteit Leiden (UL)2013Huntington's disease; Cognition; Movement disorder; Executive functioning; Memory; P300; Motor behaviour
ColoPulse tablets in inflammatory bowel disease: formulation, potential application and evaluationMaurer J.M., PhDKosterink J.G.W., prof. dr.Frijlink H.W., prof. dr.Woerdenbag H.J., dr.Rijksuniversiteit Groningen (RUG)2017ColoPulse tablets; Inflammatory bowel disease;
Communicating risk effectivelyPiening S., PhDHaaijer-Ruskamp F.M., prof. dr.Graeff P.A. de, prof. dr.Mol P.G.M., dr.Straus S.M.J.M., dr.Rijksuniversiteit Groningen (RUG)2013risk effectivity communicating risk drugs
Comorbidities, complications and treatment of childhood obesityLentferink Y.E., PhDKnibbe C.A.J., prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2019Children; Obesity; Asthma; ADHD; Insulin resistance; Metformin; Cardiovascular diseases; Obese children; Arterial stiffness; Skin autofluorescence;
COMPARE: Care in Oncolytic Medication surveillance:Pharmacovigilance, Acceptability, Risks and EventsOijen B.P.C. van, dr.Schouten H.C., prof. dr.Kuy P.H.M. van der, dr.Janknegt R., PharmD PhDUniversiteit Maastricht (UM)2015Chemotherapy; Clinical pharmacology; Pharmaceutical care;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgeryBrill M.J.E., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Continuity of pharmaceutical care for psychiatric patientsAbdullah-Koolmees H., PhDEgberts A.C.G., prof. dr.Heerdink E.R., dr.Gardarsdottir H., dr.Universiteit Utrecht (UU)2015Pharmaceutical care; Medication; Hospitalization; Somatic; Discharge; Discontinuation; Rehospitalization; Rehospitalization prediction;
Determinants of treatment outcomes in epilepsyWassenaar M., PhDEgberts A.C.G., prof. dr.Leijten F.S.S., dr.Uijl S.G., dr.Universiteit Utrecht (UU)2014Epilepsy; Treatment; Treatment outcomes; Quality of life; Patient-perspectives; Clinical determinants; Seizures; Pharmacology; Daily practice; Community-based;
Development and use of biomarkers in clinical development of new therapies for chronic airway diseaseZuiker R.G.J.ABurggraaf J., prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2016Asthma COPD Biomarkers Allergen challenges Inflammation
Diagnosis and treatment of obese children with insulin resistanceAa M.P. van der, PhDKnibbe C.A.J., prof. dr.Boer A. de, prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2016Obesity; Children; Insulin resistance; Metformin;
DNA Damage-related Vascular Dysfunction: Pathways and InterventionsBautista-Niño P.K., PhDDanser A.H.J., prof. dr.Franco Duran O.H., Prof.dr.Roks A.J.M., dr.Ghanbari M., dr.Erasmus Universiteit Rotterdam (EUR)2017Cardiovascular disease; Vascular reactivity; DNA damage;
Don't be afraid! Population PK-PD modeling as the basis for individualized dosing in children and critically illPeeters M.Y.M., dr.Danhof M., prof. dr.Tibboel D., prof. dr.Knibbe C.A.J., prof. dr.Universiteit Leiden (UL)2007Pharmacokinetics; Pharmacodynamics; Children; Sedation; Critically ill; Intensive care; NONMEM; Propofol; Midazolam;
Driving-impairing medicines and traffic safety: patients' perspectivesMonteiro S.P., PhDGier J.J. de, prof. dr.Dijk C.E.M.J. van, dr. ir.Rijksuniversiteit Groningen (RUG)2014
Drug effects on the risk and prognosis of community-acquired pneumoniaGarde E.M.W. van de, dr.Leufkens H.G.M., prof. dr.Bosch J.M.M. van den, prof. dr.Souverein P.C., dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2007Pneumonia; Adults; Clinical outcomes; Prevention;
Drug-induced psychomimetic symptoms as a model for psychosisKleinloog-Fernández González H.D., PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2014Clinical Pharmacology Psychotic Disorders Clinical Trial Drug evaluation Biological Models
Drug-related problems: risk factors and the role of clinical pharmacistsZaal R.J., PhDVulto A.G., prof. dr.Haaijer-Ruskamp F.M., prof. dr.Bemt P.M.L.A. van den, dr.Erasmus Universiteit Rotterdam (EUR)2016Drug-related problems; Risk factors;
Early phase clinical drug development for HPV-induced disorders: novel tools and treatmentsRijsbergen M.Burggraaf J., prof. dr.Rissmann R, prof.dr.Poelgeest M.I.E. van, dr.Universiteit Leiden (UL)2020HPV-induced diseases;
Effects of perioperative medication on hemodynamics and blood lossHaelst I.M.M. van, PhDEgberts A.C.G., prof. dr.Kalkman C.J., prof. dr.Klei W.A. van, prof. dr.Universiteit Utrecht (UU)2013
End-organ damage in diabetes: exploring innovative targets and therapiesHamidi M., PhDHenning R.H., prof. dr.Buikema J.H., dr.Deelman L.E., dr.Rijksuniversiteit Groningen (RUG)2015Diabetes mellitus;
Endothelial dysfunction in cardiovascular diseaseHeuvel M. van den, PhDDuncker D.J.G.M., Prof.dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2018Cardiovascular disease; Vascular reactivity; Cholesterol;
Evaluation of renal end points in nephrology trials. Weldegiorgis MLambers Heerspink H.J., prof. dr.Zeeuw D. de, prof. dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Nephrology trials; renal endpoints
Experimental focal cerebral ischemia: optimalisation of models and therapeutic interventionsShanbhag N.C., PhDHenning R.H., prof. dr.Schilling L., prof. dr.Rijksuniversiteit Groningen (RUG)2016Cerebral ischemia;
Exploring optimal pharmacotherapy after bariatic surgery: where two worlds meetYska J.P., PhDRoon E.N. van, prof. dr.Wilffert B, prof. dr.Rijksuniversiteit Groningen (RUG)2017Optimal pharmacotherapy; Bariatric surgery;
Exploring strategies to individualize treatment with aminoglycosides and co-trimoxazole for MDR TuberculosisDijkstra J.A., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2017Personalized medicine; Tuberculosis;
Exploring the role of glucagon in glucose homeostasisDongen M.G.J. van, PhDCohen A.F., prof. dr.Romijn J.A., prof drBurggraaf J., prof. dr.Universiteit Leiden (UL)2015Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
Exposure to antiretroviral agents in hiv-infected pregnant women: not too much-not too littleColbers E.P.H., PhDBurger D.M., prof. dr.Radboud Universiteit (RU)2015HIV; antiretroviral agents; clinical pharmacology; drug drug interactions
First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and childrenBrussee J.M., PhDKnibbe C.A.J., prof. dr.Wildt S.N. de, prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2018Pharmacology; Pharmacokinetics; Paediatrics; Cytochrome P450; Drug metabolism; Midazolam; Population pharmacokinetics; Semi-PBPK modelling; CYP3A-mediated metabolism; First-pass metabolism;
Fluorescence-enhanced surgical navigation : towards tailored tumor detectionBoogerd L.S.F., PhDVelde C.J.H. Van de, Prof.dr.Burggraaf J., prof. dr.Vahrmeijer A.L., Dr.Universiteit Leiden (UL)2019Fluorescence guided surgery tailored tumor detection Intraoperative tumor imaging ICG CEA targeted tumor detection
Fluorescence-guided cancer surgery:clinical translation of tumor targeted agentsHoogstins C.E.SBurggraaf J., prof. dr.Cohen A.F., prof. dr.Vahrmeijer A.L., Dr.Universiteit Leiden (UL)2018Image-guided surgery Fluorescence Tumor targeted Oncological surgery
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in childrenBellanti F., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2015Benefit-risk assessment; Paediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Future drugs in atherosclerotic cardiovascular diseasePoelgeest E.P vanBurggraaf J., prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2018Atherosclerosis Systemic inflammation Hypercholesterolemia PCSK9 inhibitor TLR4 sinaling Acute kidney injury Endothelial dysfunction Human endotoxemia model Ex vivo LPS challenge test Invivo LPS challenge test
Harmonising relative effectiveness assessments of medicines in EuropeKleijnen S., PhDBoer A. de, prof. dr.Leufkens H.G.M., prof. dr.Goettsch W.G., dr.Universiteit Utrecht (UU)2016Medicines; Relative effectiveness; Reimbursement; Harmonisation; Europe; Methods; Health technology assessment (HTA);
HIV treatment: a clinical pharmacology perspectiveLuin M. van, dr.Hekster Y.A., prof. dr.Burger D.M., prof. dr.Richter C., dr.Radboud Universiteit (RU)2010Clinical pharmacology; Pharmacokinetics; HIV; Therapeutic drug monitoring; drug-drug interactions; antiretroviral drugs
How to scale clearance from adults to children for drugs undergoing hepatic metabolism? Insights from advanced PBPK modelling and simulationCalvier E.A.M., PhDKnibbe C.A.J., prof. dr.Tibboel D., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2018Paediatrics; Clearance; Allometric scaling; Hepatic metabolism; Physiologically based pharmacokinetics; Pharmacokinetics; Optimal design; Scaling clearance;
Human in vivo studies on the non-glycaemic effects of thiazolidinedione derivativesRennings A.J.M., PhDSmits P., prof. dr.Tack C.J.J., prof. dr.Radboud Universiteit (RU)2014
Human pharmacology of current and novel gaba(a)-ergic treatments for anxietyChen X., PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Jacobs G.E., dr.Universiteit Leiden (UL)2017Anxiety Human pharmacology GABA-ergic treatment
Hypertension and renal toxicity during angiogenesis inhibition: Salt dependency and treatment optionsLankhorst S.Danser A.H.J., prof. dr.Meiracker A.H. van den, dr.Kappers M.H.W., PhDErasmus Universiteit Rotterdam (EUR)2016Hypertension; Renal function; Treatment options
Immunological aspects of conventional and new treatments for cervical cancer, an immunopharmacological approachMeir H. vanBurg S.H van der, Prof.dr.Burggraaf J., prof. dr.Kalkman C.J., prof. dr.Peeters M.Y.M., dr.2017Immunotherapy Combined chemo-immunotherapy Cervical cancer HPV16-SLP vaccination Immunomonitoring
Immunological aspects of hibernation as leads in the prevention of acute organ injury.Bouma H.R., PhDHenning R.H., prof. dr.Kroese F.G.M., prof. dr.Strijkstra A.M., dr.Rijksuniversiteit Groningen (RUG)2013hibernation acute organ injury immunological
Implementing dried blood spot sampling in transplant patient careTouw D.J., prof. dr.Touw D.J., prof. dr.Bakker S.J.L., prof. dr.Rijksuniversiteit Groningen (RUG)2020dried blood spot sampling, transplant patient care
Implementing dried spot sampling in transplant patient careVeenhof H.Touw D.J., prof. dr.Bakker S.J.L., prof. dr.Berger S.P., prof. dr.Rijksuniversiteit Groningen (RUG)2020dried blood spot; Transplantation;
Implications of the cardiomyocyte stress response on protein homeostasis in atrial fibrillationWiersma M., PhDHenning R.H., prof. dr.Brundel B.J.J.M., dr.Rijksuniversiteit Groningen (RUG)2016Atrial fibrillation;
Improving acceptance of pharmacogenetic testing in clinical careBank P.C.D., PhD PharmDGuchelaar H.J., prof. dr.Swen J.J., PhDUniversiteit Leiden (UL)2018Pharmacogenetics, pharmacogenomics, primary care, Clinical-decision-support, drug-safety
Improving the physical health of people with severe mental illness : the need for tailor made care and uniform evaluation of interventionsHasselt F.M. van, PhDLoonen A.J.M., prof. dr.Oud M.J.T., dr.Krabbe P.F.M., dr.Rijksuniversiteit Groningen (RUG)2013
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