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Displaying 101-150 of 278 results.

Titel	Promovendus	Promotor 1	Promotor 2	Copromotor 1	Copromotor 2	Universiteit	Promotiejaar	Trefwoorden

Hibernating mitochondria, the cool key to cellular protection and transplant optimization; Mitochondrial aspects of hibernators and non-hibernators in hypothermia	Hendriks K.D.W.	Henning R.H., prof. dr.	Leuverink H.G.D., prof. dr.			Rijksuniversiteit Groningen (RUG)	2021	Hibernating mitochondria
Mitochondrial failure in sepsis; Acute mechnisms and long-term consequences.	Henning R.H., prof. dr.			Bouma H.R., PhD		Rijksuniversiteit Groningen (RUG)	0	Mitrochondrial failure in Sepsis
Drug development and new targets for redox disturbances in experimental vascular disease	Henning R.H., prof. dr.			Deelman L.E., dr.	Buikema J.H., dr.	Rijksuniversiteit Groningen (RUG)	2022	Drug development, redox disturbance, experimental vascular disease
Clinical decision support in community pharmacy	Heringa M., PhD	Bouma H.R., PhD	Smet P.A.G.M. de, prof. dr.	Floor-Schreudering A., PhD PharmD		Universiteit Utrecht (UU)	2017	Patient safety; Clinical decision support system; Community pharmacy; Drug therapy;
The Clinical Pharmacology of performance enhancement and doping detection in sports	Heuberger J., dr.	Cohen A.F., prof. dr.		Groeneveld G.J., prof. dr.	Rotmans J.I., dr.	Universiteit Leiden (UL)	2019	Performance enhancement and doping detection in sports
Endothelial dysfunction in cardiovascular disease	Heuvel M. van den, PhD	Duncker D.J.G.M., Prof.dr.	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2018	Cardiovascular disease; Vascular reactivity; Cholesterol;
Towards New Therapies for Preeclampsia: Restoring Vascular Dysfunction	Hitzerd AE	Reiss IKM, prof.dr.	Danser A.H.J., prof. dr.	Simons SHP, dr.		Erasmus Universiteit Rotterdam (EUR)	2020	Pre-eclampsia; Treatment options; Pregnancy; Pharmacology;
Predicting and improving individual long-term outcome in patients with diabetes and nephropathy; dterminants of response to RAAS inhibition	Holtkamp F.A., PhD	Graeff P.A. de, prof. dr.	Zeeuw D. de, prof. dr.	Lambers Heerspink H.J., prof. dr.		Rijksuniversiteit Groningen (RUG)	2011	diabetes; nephropathy; predicting and improving long term outcome
Fluorescence-guided cancer surgery:clinical translation of tumor targeted agents	Hoogstins C.E.S	Burggraaf J., prof. dr.	Cohen A.F., prof. dr.	Vahrmeijer A.L., Dr.		Universiteit Leiden (UL)	2018	Image-guided surgery Fluorescence Tumor targeted Oncological surgery
Use of real-world evidence in pharmaeconomic analysis	Huang Y.	Haaijer-Ruskamp F.M., prof. dr.	Postma M.J., prof. dr.			Rijksuniversiteit Groningen (RUG)	2019	Pharmacogenomics;
Medication surveillance in older patients : clinical decision support as the next step in medication safety	Hurkens K.P.M.G., MD PhD MBA	Stehouwer C.D.A., prof. dr.		Kuy P.H.M. van der, dr.	Janknegt R., PharmD PhD	Universiteit Maastricht (UM)	2013	Clinical pharmacology; Elderly; clinical rules
Microvasculature, the Trigeminal System and Migraine: A focus on female sex hormones	Ibrahimi K., PhD	Danser A.H.J., prof. dr.		Maassen van den Brink A., dr.	Meiracker A.H. van den, dr.	Erasmus Universiteit Rotterdam (EUR)	2015	Migraine; Microvasculature; Trigeminal System; Female Sex Hormones
Better prediction of drug response in diabetic kidney disease	Idzerda N.M.A.	Lambers Heerspink H.J., prof. dr.	Zeeuw D. de, prof. dr.	Pena M.J., PhD		Rijksuniversiteit Groningen (RUG)	2020	Diabetic kidney disease; Drug response;
Maturation of cytochrome P450 3A mediated drug metabolism : towards individualized dosing in children	Ince I., PhD	Tibboel D., prof. dr.	Knibbe C.A.J., prof. dr.	Wildt S.N. de, prof. dr.		Erasmus Universiteit Rotterdam (EUR)	2013	Paediatrics; Midazolam; CYP3A; Population PK; Maturation; Metabolism;
Priority medicines for children : exploring age-appropriate medicines and antibiotic use in children	Ivanovska V., PhD	Leufkens H.G.M., prof. dr.		Mantel-Teeuwisse A.K., dr.	Dijk C.E.M.J. van, dr. ir.	Universiteit Utrecht (UU)	2017	Paediatric pharmacotherapy; Paediatric drug development; Priority setting; Age-appropriate formulations; Antibiotic use; Children;
Methods for improving the safety of fluoropyrimidine anticancer drugs	Jacobs B.A.W., PhD	Schellens J.H.M., prof. dr.	Beijnen J.H., prof. dr.	Nuijen B., dr.		Universiteit Utrecht (UU)	2016	Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Thymidylate synthase; Safety; Phenotyping; Circadian rhythm;
Bioanalysis and clinical pharmacology of tamoxifen in breast cancer	Jager N.G.L., PhD	Beijnen J.H., prof. dr.	Schellens J.H.M., prof. dr.	Rosing H., dr.		Universiteit Utrecht (UU)	2014	Cancer; Clinical pharmacology;
The role of aldosterone and aldosterone blockade in hypertension	Jansen P.M., PhD	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2013	Cardiovascular disease; Antihypertensive drugs; Pharmacology;
Measuring pharmacodynamics in early clinical drug studies in multiple sclerosis	Kanhai K.M.S	Cohen A.F., prof. dr.		Groeneveld G.J., prof. dr.		Universiteit Leiden (UL)	2019	Multiple sclerosis Drug development Biomarkers Remyelination
Introducing Clinical Pharmacology to Hepatitis C Therapy	Kanter C.T.M.M. de, PhD	Burger D.M., prof. dr.	Drenth J.P.H., prof. dr.	Dofferhoff A.S.M., dr.		Radboud Universiteit (RU)	2015	Hepatitis C; Clinical Pharmacology; Therapeutic drug monitoring; drug drug interactions
Cardiovascular, renal and thyroid toxicity during angiogenesis inhibition: a translational approach	Kappers M.H.W., PhD	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2011	Cancer; Pharmacology; Antihypertensive drugs;
Carotid artery contrast enhanced ultrasound	Kate G.L. ten, PhD	Sijbrands E.J.G., prof. dr.	Danser A.H.J., prof. dr.	Schinkel A.F.L., Dr.		Erasmus Universiteit Rotterdam (EUR)	2014	Cardiovascular disease; Vascular reactivity;
Antipsychotics, delirium and glucose in older patients	Keulen K. van, PhD	Egberts A.C.G., prof. dr.		Knol W., PhD	Heerdink E.R., dr.	Universiteit Utrecht (UU)	2018	Antipsychotics; Older patients; Delirium; Hypoglycemia; Hyperglycemia; Incapacitated patients; Glucose variability;
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasis	Kip A.E., PhD	Beijnen J.H., prof. dr.	Schellens J.H.M., prof. dr.	Dorlo T.P.C., dr.		Universiteit Utrecht (UU)	2017	Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin;
Harmonising relative effectiveness assessments of medicines in Europe	Kleijnen S., PhD	Boer A. de, prof. dr.	Leufkens H.G.M., prof. dr.	Goettsch W.G., dr.		Universiteit Utrecht (UU)	2016	Medicines; Relative effectiveness; Reimbursement; Harmonisation; Europe; Methods; Health technology assessment (HTA);
Minimally invasive methodology for pharmacological research involving children	Klein R.H., PhD	Cohen A.F., prof. dr.	Burggraaf J., prof. dr.	Sukhai R.N., dr.		Universiteit Leiden (UL)	2013	Paediatrics; Clinical pharmacology; ADHD; Pharmacokinetics; Growth hormone deficiency; Pharmacodynamics; Point of care technology;
Drug-induced psychomimetic symptoms as a model for psychosis	Kleinloog-Fernández González H.D., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2014	Clinical Pharmacology Psychotic Disorders Clinical Trial Drug evaluation Biological Models
Patients at increased fracture risk : identification and pharmacological treatment	Klop C., PhD	Leufkens H.G.M., prof. dr.	Bijlsma J.W.J., prof. dr.	Vries F. de, prof. dr.	Welsing P.M.J., dr.	Universiteit Utrecht (UU)	2016	Fragility fracture; Hip fracture; Hip; Osteoporosis; Biphosphonate; Absolute risk prediction; FRAX;
Novel approaches in clinical development of cannabinoid drugs	Klumpers L.E., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2014	Cannabinoids; THC; CB1 antagonists; Pharmacokinetics; Clinical pharmacology; Pharmacodynamics; Feeling high; PK-PD modelling; Resting state FMRI; Rimonabant;
Insight in disease and drug interactions, with treatment optimisation of patients with cancer	Knapen L.M., PhD	Tjan-Heijnen V.C.G., prof. dr.	Vries F. de, prof. dr.	Croes S., dr.	Erp N.P. van, dr.	Universiteit Maastricht (UM)	2019
Pharmacokinetics, pharmacodynamics and safety of different propofol formulations	Knibbe C.A.J., prof. dr.	Danhof M., prof. dr.		Aarts L.P.H.J., prof. dr.	Kuks P.F.M., dr.	Universiteit Leiden (UL)	2002	Pharmacokinetics; Pharmacodynamics; Propofol;
Antipsychotic induced parkinsonism: assessment, causes and consequences	Knol W., PhD	Egberts A.C.G., prof. dr.	Schobben A.F.A.M., prof. dr.	Marum R.J. van, prof. dr.	Jansen P.A.F., dr.	Universiteit Utrecht (UU)	2011	Antipsychotics; elderly; parkinsonism; pharmacokinetics; pharmacodynamics; pharmacogenetics; assessment
Techniques to improve neurological outcome after cardiac surgery	Kok W.F., PhD	Henning R.H., prof. dr.	Absalom A.R., prof. dr.	Scheeren T.W.L., prof. dr.		Rijksuniversiteit Groningen (RUG)	2017	Cardiac surgery; Clinical pharmacology; Neurological outcome;
Investigations of skin inflammation with a novel dermatology toolbox for early phase clinical drug development	Kolk T. van der, dr	Burggraaf J., prof. dr.		Rissmann R, prof.dr.		Universiteit Leiden (UL)	2021	Skin inflammation Dermatology toolbox Early phase clinical drug development Trial at home Inflammation models Skin microbiome Atopic dermatitis
Supporting patients : pharmacy based interventions to improve medication adherence	Kooij M.J., PhD	Bouvy M.L., prof. dr.		Heerdink E.R., dr.	Dijk C.E.M.J. van, dr. ir.	Universiteit Utrecht (UU)	2015	Medication adherence; Pharmacists; Intervention; Pharmacy; Compliance; Community pharmacy;
Pharmacokinetic insights in individual drug response; a model-based approach to quantify individual exposure-response relationships in type 2 diabetes	Koomen J.V.	Lambers Heerspink H.J., prof. dr.	Mol P.G.M., dr.	Stevens J., Dr.		Rijksuniversiteit Groningen (RUG)	2021	Pharmacokinetic insights in individual drug response; a model-based approach to quantify individual exposure-response relationships in type 2 diabetes
Towards better treatment outcomes in childhood asthma	Koster E.S., PhD	Raaijmakers J.A.M., prof. dr.		Maitland-van der Zee A.H., prof. dr.		Universiteit Utrecht (UU)	2011	Asthma; Children; Treatment Outcomes; Epidemiology;
The influence of the sample matrix on LC-MS/MS method development and analytical performance	Koster R.A., PhD	Uges D.R.A., prof. dr.	Kosterink J.G.W., prof. dr.	Alffenaar J.W.C., prof. dr.		Rijksuniversiteit Groningen (RUG)	2015
Pharmacokinetics and/or pharmacodynamics of propofol, atracurium and cefazolin in morbidly obese patients	Kralingen S. van, PhD	Knibbe C.A.J., prof. dr.		Dongen H.P.A. van, dr.	Ramshorst B. van, dr.	Universiteit Leiden (UL)	2011	Population PK; Population PD; Obesity; Propofol; Cefazolin; Morbid obesity; Bariatric surgery; Atracurium;
Challenges in the clinical development of orphan drugs	Kreeftmeijer-Vegter A.R., PhD	Boer A. de, prof. dr.		Vries P.J. de, dr.		Universiteit Utrecht (UU)	2015	Orphan drugs; Clinical development; Paediatric formulation; Pharmacokinetics; Efficacy; Safety; Regulatory;
Size does matter : drug glucuronidation in children	Krekels E.H.J., PhD	Knibbe C.A.J., prof. dr.	Tibboel D., prof. dr.			Universiteit Leiden (UL)	2012	Paediatrics; Morphine; Population PK; System-specific covariate modelling; Model validation; Glucuronidation; Ontogeny; Pharmacokinetics; UGT2B7; Zidovudine;
(Pro)renin revisited: new insights from studies in mast cells	Krop M., dr.	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2009	Cardiovascular disease; Pharmacology; Prorenin;
The association between albuminuria and long-term renal risk; how to improve the precision of drug effect estimates	Kröpelin T.F., PhD	Zeeuw D. de, prof. dr.	Lambers Heerspink H.J., prof. dr.			Rijksuniversiteit Groningen (RUG)	2016	Kidney; Diabetic kidney disease; Drug efficacy;
Intranasal drug delivery in migraine	Kuy P.H.M. van der, dr.	Merkus F.W.H.M., prof. dr.		Lohman J.J.H.M., dr.		Universiteit Leiden (UL)	2003	Migraine; Intranasal
Peripheral Projections of the Trigeminovascular System as Antimigraine Target	Labastida Ramírez A	Danser A.H.J., prof. dr.		Maassen van den Brink A., dr.		Erasmus Universiteit Rotterdam (EUR)	2019	Migraine; Vascular reactivity; Pharmacology;
Neurovascular pharmacology of migraine: epigenetics and sex hormones	Labruijere S., PhD	Danser A.H.J., prof. dr.		Maassen van den Brink A., dr.		Erasmus Universiteit Rotterdam (EUR)	2014	Pharmacology; Migraine; Epigenetics; Neurovascular pharmacology;
Pharmaceutical development, preclinical research and clinical application of the bone-targeting therapeutic radiopharmaceutical rhenium-188-HEDP	Lange R., PhD	Hendrikse N.H., prof. dr.		Heine R. ter, dr.	Bloemendal H.J., dr.	Vrije Universiteit Amsterdam (VU)	2017	Radiopharmaceutics; Pharmaceutical development; Rhenium;
Hypertension and renal toxicity during angiogenesis inhibition: Salt dependency and treatment options	Lankhorst S.	Danser A.H.J., prof. dr.		Meiracker A.H. van den, dr.	Kappers M.H.W., PhD	Erasmus Universiteit Rotterdam (EUR)	2016	Hypertension; Renal function; Treatment options
Building a clinical pharmacology framework for the safe and effective use of antifungal agents	Lempers VJC	Burger D.M., prof. dr.	Brüggemann R.J.M., PhD	Aarnoutse R.E., dr.		Radboud Universiteit (RU)	2016	Antifungal drugs; Clinical pharmacology;
Comorbidities, complications and treatment of childhood obesity	Lentferink Y.E., PhD	Knibbe C.A.J., prof. dr.		Vorst M.M.J. van der, dr.		Universiteit Leiden (UL)	2019	Children; Obesity; Asthma; ADHD; Insulin resistance; Metformin; Cardiovascular diseases; Obese children; Arterial stiffness; Skin autofluorescence;