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Displaying 1-50 of 278 results.

Titel	Promovendus	Promotor 1	Promotor 2	Copromotor 1	Copromotor 2	Universiteit	Promotiejaar	Trefwoorden

Diagnosis and treatment of obese children with insulin resistance	Aa M.P. van der, PhD	Knibbe C.A.J., prof. dr.	Boer A. de, prof. dr.	Vorst M.M.J. van der, dr.		Universiteit Leiden (UL)	2016	Obesity; Children; Insulin resistance; Metformin;
Continuity of pharmaceutical care for psychiatric patients	Abdullah-Koolmees H., PhD	Egberts A.C.G., prof. dr.		Heerdink E.R., dr.	Gardarsdottir H., dr.	Universiteit Utrecht (UU)	2015	Pharmaceutical care; Medication; Hospitalization; Somatic; Discharge; Discontinuation; Rehospitalization; Rehospitalization prediction;
Osteoporotic fractures: relation to mortality, medication use, and rheumatoid arthritis	Abtahi S., PhD	Vries F. de, prof. dr.	Boonen A.E.R.C.H., prof. dr.	Driessen J.H.M., PhD	Burden A.M., dr.	Universiteit Maastricht (UM)	2021
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation	Admiraal R., PhD	Knibbe C.A.J., prof. dr.		Boelens J.J., dr.	Bredius R.G.M., dr.	Universiteit Leiden (UL)	2017	ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy;
Pain still hurts : pain assessment and pain management in intensive care patients	Ahlers S.J.G.M., PhD	Tibboel D., prof. dr.	Knibbe C.A.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2012	Morphine; Remifentanil; Pain; Immune reconstitution; Intensive care; Critically ill; Analgesia; Anesthesiology; Pain assessment; Pain management;
Risk factors and treatment of paediatric chronic diseases - Type 1 diabetes, asthma and allergy	Ahmadizar F., PhD	Boer A. de, prof. dr.		Maitland-van der Zee A.H., prof. dr.		Universiteit Utrecht (UU)	2016	Children; Diabetes mellitus; Allergy
Revisiting co-trimoxazole for the treatment of tuberculosis	Alsaad N.S.I., PhD	Kosterink J.G.W., prof. dr.	Werf T.S. van der, prof. dr.	Alffenaar J.W.C., prof. dr.		Rijksuniversiteit Groningen (RUG)	2016	Tuberculosis;
Challenging the cholinergic system: ageing, cognition & inflammation	Alvarez-Jimenez R., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Groeneveld G.J., prof. dr.		Universiteit Leiden (UL)	2017	Neuropsychopharmacology Clinical Pharmacology Trials Cognition Dementia Cholinergis system Drug development
Integrated assessment of neurocognitive, neurophysiological and pain processing in early clinical drug development	Amerongen G. van, PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Groeneveld G.J., prof. dr.		Universiteit Leiden (UL)	2020	Clinical pharmacology Pharmacodynamics Pain Human pain models Cannabinoid GABA THC Multiple sclerosis (MS)
Preclinical targeting of the tumor microenvironment. Possibilities and consequences	Arjaans M., PhD	Vries E.G.E. de, prof. dr.		Schröder C.P., dr.	Timmer-Bosscha H., dr.	Rijksuniversiteit Groningen (RUG)	2015
Regulatory benefit-risk assessment : different perspectives	Arnardottir A.H., PhD	Haaijer-Ruskamp F.M., prof. dr.	Graeff P.A. de, prof. dr.	Mol P.G.M., dr.	Straus S.M.J.M., dr.	Rijksuniversiteit Groningen (RUG)	2013	drug registration benefit risk
ADHD medication use and long-term consequences	Ban E.F. van den, PhD	Egberts A.C.G., prof. dr.	Swaab-Barneveld J.T., prof. dr.	Heerdink E.R., dr.		Universiteit Utrecht (UU)	2014	ADHD medication use; Long-term consequences;
Improving acceptance of pharmacogenetic testing in clinical care	Bank P.C.D., PhD PharmD	Guchelaar H.J., prof. dr.		Swen J.J., PhD		Universiteit Leiden (UL)	2018	Pharmacogenetics, pharmacogenomics, primary care, Clinical-decision-support, drug-safety
Isoflurane induced eNOS signaling and cardioprotection: preconditioning mechanisms under normal and hyperglycemic conditions	Baotic I., PhD	Henning R.H., prof. dr.		Epema A.H., dr.		Rijksuniversiteit Groningen (RUG)	2018	Isoflurane; eNOS; cardioprotection
Individualization of drug exposure in pediatric hematopoietic stem cell transplantation	Bartelink I.H., PhD	Egberts A.C.G., prof. dr.	Danhof M., prof. dr.	Boelens J.J., dr.	Knibbe C.A.J., prof. dr.	Universiteit Utrecht (UU)	2012	Paediatrics; Busulfan; Hematopoietic stem cell transplantation;
Making things easier: how to improve antiviral drug treatment for children	Bastiaans D.E.T., dr.	Burger D.M., prof. dr.				Radboud Universiteit (RU)	2016	Clinical pharmacology; Antiviral drug treatment;
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factors	Batenburg W.W., dr.	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2005	Cardiovascular disease; Pharmacology;
DNA Damage-related Vascular Dysfunction: Pathways and Interventions	Bautista-Niño P.K., PhD	Danser A.H.J., prof. dr.	Franco Duran O.H., Prof.dr.	Roks A.J.M., dr.	Ghanbari M., dr.	Erasmus Universiteit Rotterdam (EUR)	2017	Cardiovascular disease; Vascular reactivity; DNA damage;
Neuropharmacology of novel dopamine modulators	Beek E.T te, PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.			Universiteit Leiden (UL)	2014	Dopamine Antagonist Drug development Pharmacokinetics Pharmacodynamics Schizophrenia Drug addiction Tachykinins
Information for rational drug prescribing to older patients : availability and applicability	Beers E., PhD	Egberts A.C.G., prof. dr.	Leufkens H.G.M., prof. dr.	Jansen P.A.F., dr.		Universiteit Utrecht (UU)	2014	Drug prescribing; Older patients; Geriatrics; Medicines; Drug safety; Information; Aged;
Sustainable use of medication : medication waste and feasibility of redispensing	Bekker C.L., PhD	Egberts A.C.G., prof. dr.	Bouvy M.L., prof. dr.	Bemt B.J.F. van den, dr.	Gardarsdottir H., dr.	Universiteit Utrecht (UU)	2018	Medication waste; UGT2B7; Unused medication; Redispensing; Pharmacy practice; Cost-benefit ratio;
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in children	Bellanti F., PhD	Danhof M., prof. dr.		Della Pasqua O.E., dr.		Universiteit Leiden (UL)	2015	Benefit-risk assessment; Paediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Albuminuria: more than a renal risk marker?	Belt S.M. van den, PhD	Zeeuw D. de, prof. dr.	Lambers Heerspink H.J., prof. dr.			Rijksuniversiteit Groningen (RUG)	2018	Albuminuria; Risk markers;
Challenges in using cardiovascular medications in Sub-Saharan Africa	Berhe D.F., PhD	Haaijer-Ruskamp F.M., prof. dr.	Taxis K., prof. dr.	Mol P.G.M., dr.		Rijksuniversiteit Groningen (RUG)	2017	Pharmacology; Medication use; Cardiovascular disease;
Optimizing treatment with psychotropic agents through precision drug therapy: It is not about the mean	Berm E.J.J., PhD	Wilffert B, prof. dr.	Hak E., prof. dr.	Maring J.G., dr.		Rijksuniversiteit Groningen (RUG)	2016	Drug therapy; Psychotropic agents; Treatment individualization; Precision medicine;
Prediction and monitoring of chronic kidney disease	Boele-Schutte E., PhD	Gansevoort R.T., prof. dr.	Wolffenbuttel B.H.R., prof. dr.	Lambers Heerspink H.J., prof. dr.	Lutgers H.L., dr.	Rijksuniversiteit Groningen (RUG)	2017	Pharmacology; Prediction; Kidney disease;
Advanced vascular imaging : technical and clinical applications in type 2 diabetes	Boer S.A. de, PhD	Kamphuisen T.P.W., prof. dr.	Slart R.H.J.A., prof. dr.			Rijksuniversiteit Groningen (RUG)	2017	Pharmacology; advanced vascular imaging; Diabetes mellitus;
Trials & tribulations : studies on the fate, transparency and efficiency of clinical drug trials	Bogert C.A. van den, PhD	Leufkens H.G.M., prof. dr.		Souverein P.C., dr.	Janssen S.W.J., dr.	Universiteit Utrecht (UU)	2017	Clinical trials; Drug development; Publication bias; Regulatory science;
Linezolid in multidrug-resistant tuberculosis	Bolhuis M.S., PhD	Werf T.S. van der, prof. dr.	Kosterink J.G.W., prof. dr.	Uges D.R.A., prof. dr.	Alffenaar J.W.C., prof. dr.	Rijksuniversiteit Groningen (RUG)	2015	Tuberculosis; Linezolid;
Fluorescence-enhanced surgical navigation : towards tailored tumor detection	Boogerd L.S.F., PhD	Velde C.J.H. Van de, Prof.dr.	Burggraaf J., prof. dr.	Vahrmeijer A.L., Dr.		Universiteit Leiden (UL)	2019	Fluorescence guided surgery tailored tumor detection Intraoperative tumor imaging ICG CEA targeted tumor detection
Red wine polyphenols and vascular function	Botden I.P.G., PhD	Danser A.H.J., prof. dr.	Sijbrands E.J.G., prof. dr.	Langendonk J.G., dr.		Erasmus Universiteit Rotterdam (EUR)	2012	Antihypertensive drugs; Cardiovascular disease; Pharmacology;
Immunological aspects of hibernation as leads in the prevention of acute organ injury.	Bouma H.R., PhD	Henning R.H., prof. dr.	Kroese F.G.M., prof. dr.	Strijkstra A.M., dr.		Rijksuniversiteit Groningen (RUG)	2013	hibernation acute organ injury immunological
Salt, acid, and the renin-angiotensin system in chronic kidney disease	Bovée D.M., PhD	Hoorn E.J., prof. dr.	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2021	Renin-angiotensin system; Kidney; Pharmacology;
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacology	Brake L.H.M. te, PHD	Burger D.M., prof. dr.	Russel F.G.M., prof. dr.	Aarnoutse R.E., dr.	Koenderink JB, dr. ir.	Radboud Universiteit (RU)	2016	Tuberculosis; Clinical pharmacology;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery	Brill M.J.E., PhD	Knibbe C.A.J., prof. dr.		Dongen H.P.A. van, dr.	Ramshorst B. van, dr.	Universiteit Leiden (UL)	2016	Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Rational prescribing in Europe: are future doctors well prepared?	Brinkman D.J., PhD	Agtmael M.A. van, prof. dr.		Richir M.C., MD PhD	Tichelaar J., dr.	Vrije Universiteit Amsterdam (VU)	2018	Clinical pharmacology; Pharmacotherapy; Prescribing;
Biomedical engineering for breathomics: towards clinical application in respitaroty diseases biomarker, instruments and Technology Readiness Levels	Brinkman P., PhD	Sterk P.J., prof. dr.	Maitland-van der Zee A.H., prof. dr.	Jongh F.H.C. de, dr.ir.		Universiteit van Amsterdam (UvA)	2019
Thermopharmacology of anticonvulsive treatment after perinatal asphyxia	Broek M.P.H. van den, PhD	Egberts A.C.G., prof. dr.		Rademaker C.M.A., dr.		Universiteit Utrecht (UU)	2013	PK-PD modelling; Newborns; Thermopharmacology; Convulsions;
Unravelling the link between diabetes, insulin treatment and breast cancer	Bronsveld H.K., PhD	Boer A. de, prof. dr.	Bruin M.L. de, prof. dr.	Schmidt M.K., dr. ir.		Universiteit Utrecht (UU)	2017	Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment;
The road to tailor made azole antifungal therapy	Brüggemann R.J.M., PhD	Burger D.M., prof. dr.	Verweij P.E., prof. dr.	Blijlevens N.M.A., dr.		Radboud Universiteit (RU)	2011	Antifungal; clinical pharmacology
First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children	Brussee J.M., PhD	Knibbe C.A.J., prof. dr.	Wildt S.N. de, prof. dr.	Krekels E.H.J., PhD		Universiteit Leiden (UL)	2018	Pharmacology; Pharmacokinetics; Paediatrics; Cytochrome P450; Drug metabolism; Midazolam; Population pharmacokinetics; Semi-PBPK modelling; CYP3A-mediated metabolism; First-pass metabolism;
How to scale clearance from adults to children for drugs undergoing hepatic metabolism? Insights from advanced PBPK modelling and simulation	Calvier E.A.M., PhD	Knibbe C.A.J., prof. dr.	Tibboel D., prof. dr.	Krekels E.H.J., PhD		Universiteit Leiden (UL)	2018	Paediatrics; Clearance; Allometric scaling; Hepatic metabolism; Physiologically based pharmacokinetics; Pharmacokinetics; Optimal design; Scaling clearance;
Clinical manifestations of sex hormonal influences in migraine	Casteren D.S. van, PhD	Danser A.H.J., prof. dr.	Terwindt G.M., prof. dr.	Maassen van den Brink A., dr.		Universiteit Leiden (UL)	2021	Migraine; Clinical pharmacology; Treatment; Endocrinology; Pharmacology;
Cardiac aldosterone: origin and effects	Chai W., dr.	Danser A.H.J., prof. dr.				Erasmus Universiteit Rotterdam (EUR)	2005	Cardiovascular disease; Pharmacology;
Neurovascular pharmacology of prospective antimigraine drugs	Chan K.Y., PhD	Danser A.H.J., prof. dr.		Maassen van den Brink A., dr.		Erasmus Universiteit Rotterdam (EUR)	2011	Pharmacology; Migraine; Neurovascular pharmacology;
Human pharmacology of current and novel gaba(a)-ergic treatments for anxiety	Chen X., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Jacobs G.E., dr.		Universiteit Leiden (UL)	2017	Anxiety Human pharmacology GABA-ergic treatment
Exposure to antiretroviral agents in hiv-infected pregnant women: not too much-not too little	Colbers E.P.H., PhD	Burger D.M., prof. dr.				Radboud Universiteit (RU)	2015	HIV; antiretroviral agents; clinical pharmacology; drug drug interactions
The role of glomerular filtration and active tubular secretion in predicting renal clearance of drugs in children using population pharmacokinetic and physiology-based pharmacokinetic modeling approaches: unspinning the yarn	Cristea S., PhD	Knibbe C.A.J., prof. dr.	Allegaert K., prof. dr.	Krekels E.H.J., PhD		Universiteit Leiden (UL)	2021	Population PK; Optimise drug dosing; Paediatric renal clearance; PBPK; Paediatrics; Renal clearance; Population pharmacokinetics; Physiologically based pharmacokinetics; Maturation; Active tubular secretion; Renal transporters;
New insights into the role of breast cancer resistance protein in endocrine and metabolic processes	Dankers A.C.A., PhD	Russel F.G.M., prof. dr.	Sweep C.G.J., prof. dr.	Masereeuw R., prof. dr.		Radboud Universiteit (RU)	2014	Cancer; Breast cancer;
A quest to optimize the clinical pharmacology of tuberculosis and human immunodeficiency virus drug treatment	Daskapan A., PhD	Werf T.S. van der, prof. dr.	Alffenaar J.W.C., prof. dr.	Stienstra Y., prof. dr.		Rijksuniversiteit Groningen (RUG)	2018	Tuberculosis; Immunodeficiency virus drug treatment