Overzicht Proefschriften
Tips in using the search/filter fieldsDisplaying 151-200 of 278 results.
Titel | Promovendus | Promotor 1 | Promotor 2 | Copromotor 1 | Copromotor 2 | Universiteit | Promotiejaar | Trefwoorden |
---|---|---|---|---|---|---|---|---|
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthma | Leusink M., PhD | Boer A. de, prof. dr. | Bakker P.I.W. de, prof. dr. | Maitland-van der Zee A.H., prof. dr. | Onland-Moret N.C., dr. | Universiteit Utrecht (UU) | 2015 | Pharmacogenomics; Cardiovascular disease; Asthma; Genomics; Genetics; Pharmacology; Statins; Inhaled corticosteroids; Cholesterol; |
Adverse drug reactions in individual patient care : documentation and prevention of represcription | Linden C.M.J. van der, PhD | Korsten H.H.M., prof. dr. | Egberts A.C.G., prof. dr. | Jansen P.A.F., dr. | Grouls R.J.E., dr. | Technische Universiteit Eindhoven (TUE) | 2013 | Adverse drug reactions; Patient care; Prevention; Represcription; |
The (pro)renin receptor: moving away from prorenin? | Lu X., PhD | Danser A.H.J., prof. dr. | Meima M.E., dr. | Erasmus Universiteit Rotterdam (EUR) | 2014 | Cardiovascular disease; Pharmacology; Prorenin; | ||
Optimizing protease inhibitor-based antiretroviral therapy for HIV-1 infected Thai adults and children | Lugt J. van der, dr. | Lange J.M.A., prof. dr. | Ananworanich J., dr. | Burger D.M., prof. dr. | Universiteit van Amsterdam (UvA) | 2010 | Antiretroviral; HIV; Pharmacokinetics; Clinical pharmacology; therapeutic drug monitoring | |
HIV treatment: a clinical pharmacology perspective | Luin M. van, dr. | Hekster Y.A., prof. dr. | Burger D.M., prof. dr. | Richter C., dr. | Radboud Universiteit (RU) | 2010 | Clinical pharmacology; Pharmacokinetics; HIV; Therapeutic drug monitoring; drug-drug interactions; antiretroviral drugs | |
Precision anticoagulation with vitamin K antagonists in children | Maagdenberg H., PhD | Boer A. de, prof. dr. | Maitland-van der Zee A.H., prof. dr. | Bierings M.B., dr. | Universiteit Utrecht (UU) | 2018 | Anticoagulation; Thrombosis; Bleedings; Children; Adolescents; Pharmacogenetics; Acenocoumarol; Phenprocoumon; Personalized medicine; Medicines; | |
Strategies for optimization of aminoglycoside and vancomycin therapies | Maarseveen E.M. van, PhD | Neef C., prof. dr. | Touw D.J., prof. dr. | Zanten A.R. van, dr. | 2014 | |||
Optimization of electronic prescribing in pediatric patients | Maat B., PhD | Egberts A.C.G., prof. dr. | Vught A.J. van, prof. dr. | Rademaker C.M.A., dr. | Bollen C.W., dr. | Universiteit Utrecht (UU) | 2014 | Children; Paediatrics; Electronic prescribing; |
Adverse drug reactions of angiotensin-converting enzyme inhibitors : towards precicion medicine | Mahmoud Pour S.H., PhD | Boer A. de, prof. dr. | Asselbergs F.W., prof. dr. MD FES | Maitland-van der Zee A.H., prof. dr. | Universiteit Utrecht (UU) | 2016 | Adverse drug reaction; Pharmacoepidemiology; Pharmacovigilance; ACE Inhibitors | |
Monitoring patients using clozapine | Man W.H., PhD | Egberts A.C.G., prof. dr. | Solinge W.W. van, prof. dr. | Wilting I., dr. | Heerdink E.R., dr. | Universiteit Utrecht (UU) | 2018 | Biomarkers; Adherence; Monitoring; Sialorrhea; Inflammation; Glycopyrrolate; Schizophrenia; Antipsychotics; Pharmacovigilance; |
ColoPulse tablets in inflammatory bowel disease: formulation, potential application and evaluation | Maurer J.M., PhD | Kosterink J.G.W., prof. dr. | Frijlink H.W., prof. dr. | Woerdenbag H.J., dr. | Rijksuniversiteit Groningen (RUG) | 2017 | ColoPulse tablets; Inflammatory bowel disease; | |
The role of differentiation factor 15 in diabetic kidney injury | Mazagová M., PhD | Henning R.H., prof. dr. | Deelman L.E., dr. | Rijksuniversiteit Groningen (RUG) | 2012 | Diabetic kidney disease; Growth differentiation factor 15; | ||
Anti sense and sensibility : renal and skin effects of (antisense) oligonucleotides | Meer, van L., Dr. | Cohen A.F., prof. dr. | Burggraaf J., prof. dr. | Moerland M., dr. | Universiteit Leiden (UL) | 2017 | Oligonucleotide Antisense Type 2 diabetes mellitus Clinical trial Phase2study | |
Characterization of vascular 5-hydroxytryptamine, adrenergic and CGRP receptors in relation to migraine | Mehrotra S., dr. | Saxena P.R., prof. dr. | Danser A.H.J., prof. dr. | Maassen van den Brink A., dr. | Erasmus Universiteit Rotterdam (EUR) | 2006 | Cardiovascular disease; Pharmacology; | |
Pharmacological modulation of ischemia and reperfusion injury | Meijer P., PhD | Rongen G.A., prof. dr. | Smits P., prof. dr. | Radboud Universiteit (RU) | 2012 | Ischemia/Reperfusion injury; rosuvastatin; adenosine; forearm; | ||
Loss of proteostasis as a substrate for Atrial Fibrilation. | Meijering R.A.M., PhD | Henning R.H., prof. dr. | Brundel B.J.J.M., dr. | Rijksuniversiteit Groningen (RUG) | 2014 | Atrial fibrillation; Proteostasis; | ||
Immunological aspects of conventional and new treatments for cervical cancer, an immunopharmacological approach | Meir H. van | Burg S.H van der, Prof.dr. | Burggraaf J., prof. dr. | Kalkman C.J., prof. dr. | Peeters M.Y.M., dr. | 2017 | Immunotherapy Combined chemo-immunotherapy Cervical cancer HPV16-SLP vaccination Immunomonitoring | |
Lithium in older patients : treatment patterns and somatic adverse effects | Melick E.J.M. van, PhD | Egberts A.C.G., prof. dr. | Wilting I., dr. | Universiteit Utrecht (UU) | 2014 | Lithium; Older patients; Pharmacodynamics; Pharmacokinetics; Antidepressants; | ||
Multi dose drug dispensing for older patients in primary care | Mertens B.J., PhD | Bouvy M.L., prof. dr. | Marum R.J. van, prof. dr. | Kwint H.F., dr. | Universiteit Utrecht (UU) | 2019 | Elderly; Primary care; Multi-dose drug dispensing; | |
Medication optimisation : methodological aspects and new strategies | Mestres Gonzalvo C., PhD | Verhey F.R., prof.dr. | Kuy P.H.M. van der, dr. | Janknegt R., PharmD PhD | Universiteit Maastricht (UM) | 2018 | Elderly; Geriatrics; Hospital pharmacists; Medication use; Model-based; Model validation; Older patients; Optimal pharmacotherapy; Pharmaceutical care; Pharmacotherapy; Pharmacovigilance; | |
Off-target effects of RAAS-inhibition: importance on renal outcomes in patients with diabetes | Miao Y., PhD | Groen A.K., prof. dr. | Zeeuw D. de, prof. dr. | Rijksuniversiteit Groningen (RUG) | 2012 | RAAS-inhibition; Diabetes mellitus; | ||
Aortic pathology and the role of the renin-angiotensin system | Molzer E., PhD | Danser A.H.J., prof. dr. | Erasmus Universiteit Rotterdam (EUR) | 2011 | Pharmacology; Cardiovascular disease; Renin-angiotensin system; | |||
Driving-impairing medicines and traffic safety: patients' perspectives | Monteiro S.P., PhD | Gier J.J. de, prof. dr. | Dijk C.E.M.J. van, dr. ir. | Rijksuniversiteit Groningen (RUG) | 2014 | |||
Population pharmacokinetics of antibiotics to prevent group B streptococcal disease: from mother to neonate | Muller A.E., dr. | Danhof M., prof. dr. | Steegers E.A.P., prof. dr. | Dörr P.J., prof. dr. | Mouton J.W., prof. dr. | Universiteit Leiden (UL) | 2009 | Population PK; Antibiotics; Group B streptococcal infections; Pregnant women; Newborns; GBS (Group B streptococcus); |
Clinical pharmacology of nevirapine in HIV-infected patients in Tanzania | Muro E.P., PhD | Burger D.M., prof. dr. | Dolmans W.M.V., prof. dr. | Radboud Universiteit (RU) | 2014 | Clinical pharmacology; HIV; Pharmacokinetics; therapy drug monitoring | ||
Monitoring patients using psychotropic drugs | Nederlof M., PhD | Egberts A.C.G., prof. dr. | Heerdink E.R., dr. | Universiteit Utrecht (UU) | 2018 | Therapeutic drug monitoring; Biomarkers; Benefit-risk assessment; Psychotropic drugs; Psychiatry; Antidepressants; Antipsychotics | ||
Medication safety in Vietnamese hospital: a focus on medication errors and safety culture | Nguyen T.H., PhD | Taxis K., prof. dr. | Haaijer-Ruskamp F.M., prof. dr. | Brouwers J.R.B.J., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2014 | ||
Osteoarthritis : association with diabetes mellitus, and treatment-related outcomes | Nielen J.T.H., PhD | Boonen A.E.R.C.H., prof. dr. | Dagnelie P.C., prof. dr. | Vries F. de, prof. dr. | Bemt B.J.F. van den, dr. | Universiteit Maastricht (UM) | 2018 | Osteoarthritis; Diabetes mellitus; Hip; Knee; Treatment outcomes; |
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studies | Nijenhuis C.M., PhD | Beijnen J.H., prof. dr. | Schellens J.H.M., prof. dr. | Rosing H., dr. | Universiteit Utrecht (UU) | 2016 | ||
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safety | Noorsyahdy A.Y., MD PhD | Boer A. de, prof. dr. | Klungel O.H., prof. dr. | Deneer V.H.M., dr. | Universiteit Utrecht (UU) | 2017 | Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics; | |
The pursuit of user-friendly medicines : older people in the hot seat | Notenboom K., PhD | Bouvy M.L., prof. dr. | Leufkens H.G.M., prof. dr. | Universiteit Utrecht (UU) | 2017 | Usability; User-friendly; Older patients; Elderly; Medicines; Medication use; Medication errors; Tablet breaking; Swallowing; Medication packaging; | ||
COMPARE: Care in Oncolytic Medication surveillance:Pharmacovigilance, Acceptability, Risks and Events | Oijen B.P.C. van, dr. | Schouten H.C., prof. dr. | Kuy P.H.M. van der, dr. | Janknegt R., PharmD PhD | Universiteit Maastricht (UM) | 2015 | Chemotherapy; Clinical pharmacology; Pharmaceutical care; | |
The use of a battery of evoked pain models in early phase drug development | Okkerse P. | Cohen A.F., prof. dr. | Groeneveld G.J., prof. dr. | Universiteit Leiden (UL) | 2018 | Pain Human pain models Analgesics Clinical pharmacology Pharmacodynamics Drug Development | ||
Treatment adherence in hypertension : methodological aspects and new strategies | Onzenoort H.A.W. van, PhD | Leeuw P.W. de, prof. dr. | Neef C., prof. dr. | Kuy P.H.M. van der, dr. | Universiteit Maastricht (UM) | 2012 | Clinical pharmacology; hypertension; compliance | |
Biomarkers in real-life COPD management | Oshagbemi O.A., PhD | Wouters E.F.M., prof. dr. | Vries F. de, prof. dr. | Franssen F.M.E., dr. | Universiteit Maastricht (UM) | 2019 | ||
Don't be afraid! Population PK-PD modeling as the basis for individualized dosing in children and critically ill | Peeters M.Y.M., dr. | Danhof M., prof. dr. | Tibboel D., prof. dr. | Knibbe C.A.J., prof. dr. | Universiteit Leiden (UL) | 2007 | Pharmacokinetics; Pharmacodynamics; Children; Sedation; Critically ill; Intensive care; NONMEM; Propofol; Midazolam; | |
Novel biomarker panels in diabetic kidney disease: predicting disease progression and response to therapy, and monitoring drug effect | Pena M.J., PhD | Zeeuw D. de, prof. dr. | Lambers Heerspink H.J., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2015 | Biomarkers; Diabetes mellitus; Kidney; | ||
Methodological approaches to the pharmacogenomics of statins | Peters B.J.M., dr. | Boer A. de, prof. dr. | Maitland-van der Zee A.H., prof. dr. | Klungel O.H., prof. dr. | Universiteit Utrecht (UU) | 2010 | Methodology; Statins; Pharmacogenomics; | |
Variability in drug response: personalized diabetes care | Petrykiv S.I. | Lambers Heerspink H.J., prof. dr. | Zeeuw D. de, prof. dr. | Laverman G.D., dr. | Rijksuniversiteit Groningen (RUG) | 2017 | ||
Adherence to antiretroviral combination therapy in children : what a difference half a day makes... | Piana C., PhD | Danhof M., prof. dr. | Della Pasqua O.E., dr. | Universiteit Leiden (UL) | 2013 | Paediatrics; Antiretroviral combination therapy; Compliance; Antiretroviral drugs; Paediatric populations; Drug combinations; Model-based; Covariate analysis; Predictive pharmacokinetic models; Clinical trial simulations; Adherence; Forgiveness of non-adherence; | ||
Communicating risk effectively | Piening S., PhD | Haaijer-Ruskamp F.M., prof. dr. | Graeff P.A. de, prof. dr. | Mol P.G.M., dr. | Straus S.M.J.M., dr. | Rijksuniversiteit Groningen (RUG) | 2013 | risk effectivity communicating risk drugs |
Future drugs in atherosclerotic cardiovascular disease | Poelgeest E.P van | Burggraaf J., prof. dr. | Cohen A.F., prof. dr. | Universiteit Leiden (UL) | 2018 | Atherosclerosis Systemic inflammation Hypercholesterolemia PCSK9 inhibitor TLR4 sinaling Acute kidney injury Endothelial dysfunction Human endotoxemia model Ex vivo LPS challenge test Invivo LPS challenge test | ||
Preclinical molecular imaging of target expression and target dynamics in cancer. | Pool M., PhD | Vries E.G.E. de, prof. dr. | Lub-de Hooge M.N., dr. | Terwisscha van Scheltinga A.G.T., PhD | Rijksuniversiteit Groningen (RUG) | 2017 | ||
The aging cardiovascular system: genetic and epigenetic determinants of vascular outcomes and cardiometabolic risk | Portilla Fernández E | Danser A.H.J., prof. dr. | Ikram MA, prof.dr. | Roks A.J.M., dr. | Dehghan A, dr. | Erasmus Universiteit Rotterdam (EUR) | 2019 | Cardiac aging; Cardiovascular disease; Genetics; Epidemiology; Epigenetics; Vascular reactivity; Pharmacology; |
Therapeutic drug monitoring: how to improve moxifloxacin exposure in tuberculosis patients | Pranger A. | Kosterink J.G.W., prof. dr. | Werf T.S. van der, prof. dr. | Uges D.R.A., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2018 | drug monitoring moxifloxacin exposure tuberculosis | |
Individualized dosing of calcineurin inhibitors in renal transplantation | Press R.R., PhD | Guchelaar H.J., prof. dr. | Fijter J.W. de, prof. dr. | Ploeger B.A., dr. | Universiteit Leiden (UL) | 2011 | Kidney; Transplantation; Calcineurin inhibitors; | |
Metabolic effects of hormonal contraceptives | Rad M. | Cohen A.F., prof. dr. | Burggraaf J., prof. dr. | Universiteit Leiden (UL) | 2015 | Venous thrombo-embolism Discriminant analysis Extended-regimen Contraceptive vaginal ring Oral contraceptives | ||
Optmizing long-term care for hiv-infected patients in Thailand | Ramautarsing R.A., PhD | Burger D.M., prof. dr. | Wit F.W.N.M., dr. | Wijgert J.H.H.M. van de, dr. | Universiteit van Amsterdam (UvA) | 2013 | HIV; clinical pharmacology | |
Sticky & Dirty Proteins- or on the poorly characterised, peculiar, pharmacokinetic and immunostimulatory aspects of biopharmaceuticals | Reijers J.A.A. | Burggraaf J., prof. dr. | Cohen A.F., prof. dr. | Universiteit Leiden (UL) | 2018 | Biopharmaeuticals Biologics Clinical Pharmacology Pharmacokinetics Adverse immunostimulation Immunotoxicity Drug impurity Drug contamination Monoclonal antibody | ||
Human in vivo studies on the non-glycaemic effects of thiazolidinedione derivatives | Rennings A.J.M., PhD | Smits P., prof. dr. | Tack C.J.J., prof. dr. | Radboud Universiteit (RU) | 2014 |