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Displaying 51-100 of 270 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Paving ways for personalizing drug therapy during pregnancyDaud N.A.A., PhDWilffert B, prof. dr.Kammen-Bergman J.E.H. van, dr.Rijksuniversiteit Groningen (RUG)2017Personalized medicine; Drug therapy; Pregnancy;
Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in childrenDe Cock R.F.W., PhDKnibbe C.A.J., prof. dr.Danhof M., prof. dr.Allegaert K., prof. dr.Universiteit Leiden (UL)2014Paediatrics; Population PK; Aminoglycosides; Propylene glycol; GFR; Renal function; Antibiotics; Glomerular filtration; Developmental changes; Pharmacokinetics; Newborns;
Treatment optimization of fluoropyrimidines as single agent and in combination therapyDeenen M.J., PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Cats A., dr.Universiteit Utrecht (UU)2011Pharmacogenetics; Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Dihydropyrimidine dehydrogenase; DPD-deficiency;
Pharmacogenetics of sunitinib in metastatic renal cell carcinomaDiekstra M.H.M., drGuchelaar H.J., prof. dr.Swen J.J., PhDUniversiteit Leiden (UL)2017Genetics; Pharmacogenetics; Renal function;
Clinical pharmacological aspects of mitochondrial function in muscle Diemen M.P.J. van, PhDCohen A.F., prof. dr.Nelissen R.G.H.H., prof. dr.Groeneveld G.J., prof. dr.Universiteit Leiden (UL)2021Clinical pharmacology; Huntington's disease; Mitochondrial function; Magnetic Resonance Spectroscopy; Sarcopenia; Phosphocreatine recovery rate; Knee; Total knee arthroplasty; Wearables; Peripheral blood mononuclear cells; Protoporphorin IX Triple State Lifetime techn;
The influence of morbid obesity on the pharmacokinetics and pharmacodynamics of drugs in adolescents and adults : focus on propofol and nadroparinDiepstraten J., PhDKnibbe C.A.J., prof. dr.Vinks A.A., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2013Drug dosing; Low-molecular-weight heparines; Nadroparin; Obesity; Pharmacodynamics; Pharmacokinetics; Propofol;
Rational use of antibioticsDijkmans A.C.Burggraaf J., prof. dr.Universiteit Leiden (UL)2020Antibiotics; Pharmacokinetics;Flucloxacillin;Penicillin; Pheneticillin;Rifampin;Colistin;Fosfomycin
Exploring strategies to individualize treatment with aminoglycosides and co-trimoxazole for MDR TuberculosisDijkstra J.A., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2017Personalized medicine; Tuberculosis;
Clinical pharmacology of immuno-modulatory biotherapeutics : innovations in early drug developmentDillingh M.R., PhDBurggraaf J., prof. dr.Cohen A.F., prof. dr.Moerland M., dr.Universiteit Leiden (UL)2017Immuno-modulatory biotherapeutics; Drug development;
Exploring the role of glucagon in glucose homeostasisDongen M.G.J. van, PhDCohen A.F., prof. dr.Romijn J.A., prof drBurggraaf J., prof. dr.Universiteit Leiden (UL)2015Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
Appropriate prescribing for older peopleDrenth-van Maanen A.C., PhDEgberts A.C.G., prof. dr.Jansen P.A.F., dr.Marum R.J. van, prof. dr.Universiteit Utrecht (UU)2013Prescribing; Elderly; Polypharmacy; Transitional pharmaceutical care;
Unintended effects of anti-hyperglycaemic drugs studied in population-based cohortsDriessen J.H.M., PhDBergh J.P.W. van den, prof. dr.Vries F. de, prof. dr.Onzenoort H.A.W. van, PhDUniversiteit Maastricht (UM)2017Hyperglycaemic drugs; Population-based;
Vascular adaptation to pregnancy and relaxinDrongelen J. van, PhDSmits P., prof. dr.Lotgering F.K., prof. dr.Radboud Universiteit (RU)2014
The role of endogenous H2S production during hybernation and forced hypothermia: towards safe cooling and rewarming in clinical practiceDugbartey G.J., PhDHenning R.H., prof. dr.Bouma H.R., PhDRijksuniversiteit Groningen (RUG)2015
Assessing long-term and rare adverse effects of medicinesDuijnhoven R.G., PhDBoer A. de, prof. dr.Hoes A.W., prof. dr.Bruin M.L. de, prof. dr.Straus S.M.J.M., dr.Universiteit Utrecht (UU)2016Adverse effects; Case-control studies; Clinical trials; Cohort studies; Long-term consequences; Medicines; Regulatory;
Vascular aging from DNA damage to protectionĎurik M., PhDDanser A.H.J., prof. dr.Roks A.J.M., dr.Erasmus Universiteit Rotterdam (EUR)2012Cardiovascular disease; Pharmacology;
Tetrahydrocannabinol in the treatment of neuropsychiatric symptoms in dementiaElsen G. van den, PhDOlde Rikkert M., prof. dr.Verkes R., prof. dr.Marck M. van der, dr. ir.Kramers C., dr.Radboud Universiteit (RU)2016THC; geriatric medicine; pain; Dementia;
Therapeutic drug monitoring in tuberculosis treatmentElsen S.H.J. van denAlffenaar J.W.C., prof. dr.Werf T.S. van der, prof. dr.Rijksuniversiteit Groningen (RUG)2020drug monitoring, tuberculosis treatment
Pharmacokinetics and optimal exposure of antifungal drugs in critically ill patientsElst K.C.M. van der, PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2015
Readmission to primary care : the role of community pharmacists post-dischargeEnsing H.T., PhDBouvy M.L., prof. dr.Koster E.S., PhDDooren A.A. van, dr.Universiteit Utrecht (UU)2017Safety; Care continuity; Discharge; Pharmacist home visit;
Unraveling the complexities of the renin-angiotensin system: from ACE to renin inhibitionEsch J.H.M. van, dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2008Cardiovascular disease; Pharmacology; Renin-angiotensin system;
The quantification of growth hormone secretion : application of model-informed drug development in acromegalyEsdonk M.J vanGraaf P.H., Prof.dr.Burggraaf J., prof. dr.Stevens J., Dr.Universiteit Leiden (UL)2019Endocrinology Pulsatile profiles Population modelling Pharmacokinetic Pharmacodynamic modelling Clinical trial simulation
Pediatric type 1 and 2 diabetes mellitus : epidemiology, comorbidities, and medication utilizationFazeli Farsani S., PhDBoer A. de, prof. dr.Knibbe C.A.J., prof. dr.Vorst M.M.J. van der, dr.Mantel-Teeuwisse A.K., dr.Universiteit Utrecht (UU)2015Adolescents; Children; Comorbidities; Epidemiology; Medication use; Diabetes mellitus; UIPS;
Drug effects on the risk and prognosis of community-acquired pneumoniaGarde E.M.W. van de, dr.Leufkens H.G.M., prof. dr.Bosch J.M.M. van den, prof. dr.Souverein P.C., dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2007Pneumonia; Adults; Clinical outcomes; Prevention;
Optimizing cancer therapy. A focus on molecular imagingGaykema S.B.M., PhDVries E.G.E. de, prof. dr.Lub-de Hooge M.N., dr.Rijksuniversiteit Groningen (RUG)2014
Clinical pharmacology of genotype-directed anticancer therapy - Towards rational combination strategiesGeel R.M.J.M. van, PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Huitema A.D.R., prof. dr.Cats A., dr.Universiteit Utrecht (UU)2016Cancer; Genetics; BRAF; Colorectal cancer; Combination therapy; p53-deficient ovarian cancer; AZD1775; Treatment individualization;
The more complex renin-angiotensin system: new insights into an old systemGembardt F., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Renin-angiotensin system;
Integrated pharmaceutical care: cooperation between pharmacist, general practioner, and patient and the development of a pharmaceutical care planGeurts M.M.E., PhDGier J.J. de, prof. dr.Brouwers J.R.B.J., prof. dr.Graeff P.A. de, prof. dr.Rijksuniversiteit Groningen (RUG)2015
Optimizing levofloxacin dose in the treatment of multidrug-resistant tuberculosisGhimire S.Alffenaar J.W.C., prof. dr.Touw D.J., prof. dr.Werf T.S. van der, prof. dr.Rijksuniversiteit Groningen (RUG)2019
Sex hormones and cardiometabolic riskGlisic M., PhDDanser A.H.J., prof. dr.Franco Duran O.H., Prof.dr.Roks A.J.M., dr.Erasmus Universiteit Rotterdam (EUR)2018Epidemiology; Pharmacology; Risk factors; Sex hormonesCardiovascular disease; Metabolism;
Renin-Synthesizing Cells and BeyondGoes Martini A., PhDDanser A.H.J., prof. dr.Neves F.A.R., prof. dr.Erasmus Universiteit Rotterdam (EUR)2017Renin-angiotensin system; Renal function;
Mounting an attack on the glioblastoma triad : proliferation, invasion and resistanceGooijer M.C. de, PhDBeijnen J.H., prof. dr.Tellingen O. van, dr.Universiteit Utrecht (UU)2019Glioblastoma; Blood-brain barrier; Therapy development; Pharmacology; Cell biology; Combination therapy; Mouse models;
Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics: Tools of the tradeGoulooze S.C., PhDKnibbe C.A.J., prof. dr.Hankemeier T., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2020Population pharmacokinetics-pharmacodynamics; Repeated time-to-event modelling; Paediatric pharmacology; Pharmacometric methodology; Analgesia; Iatrogenic withdrawal; Postoperative pain; Item response theory (IRT); Analgesia and sedation; Real-world data; Paediatrics; Pharmacodynamics; Pharmacometrics;
The role of efflux and influx transporters in the disposition of digitalis-like compoundsGozalpour E., PhDRussel F.G.M., prof. dr.Radboud Universiteit (RU)2015
Towards better fall prevention - examining the interplay between factors that influence gait in older patientsGroot M.H. de, PhDBeijnen J.H., prof. dr.Lamoth C.J.C., dr.Universiteit Utrecht (UU)2017Falls; Gait analysis; Accelerometry; Frailty; Osteoporosis; Maturation; Medication use; Medication use; Geriatrics; Older patients;
Acute and chronic pain after cardiac surgeryGulik L. van, PhDKnibbe C.A.J., prof. dr.Tibboel D., prof. dr.Bruins P., dr.Universiteit Leiden (UL)2014Acute pain; Intensive Care Unit; Chronic pain; Cardiac surgery; Pain management;
Vascular pharmacology of migraine and preeclampsia: Problems of the fair sexGupta S., dr.Saxena P.R., prof. dr.Danser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2006Cardiovascular disease; Pharmacology;
Cardiovascular molecular imagingHaas H.J. de, PhDDierckx R.A.J.O., prof. dr.Slart R.H.J.A., prof. dr.Boersma H.H., dr.Rijksuniversiteit Groningen (RUG)2018Pharmacology; Cardiovascular molecular imaging
Effects of perioperative medication on hemodynamics and blood lossHaelst I.M.M. van, PhDEgberts A.C.G., prof. dr.Kalkman C.J., prof. dr.Klei W.A. van, prof. dr.Universiteit Utrecht (UU)2013
Adequate antimicrobial treatment in elderly patientsHaeseker M.B., PhDVerbon A., prof. dr.Bruggeman C.A.M.V.A., prof. dr.Hoebe C.J.P.A., prof. dr.Stolk L.M.L., drUniversiteit Maastricht (UM)2015Antibiotics; Elderly; Drug dosing;
The role of pharmacogenetics in osteosarcomaHagleitner M.M., PhDHoogerbrugge P.M., prof. dr.Guchelaar H.J., prof. dr.Loo D.M.W.M. te, dr.Coenen M.J.H., dr.Radboud Universiteit (RU)2015Cancer; Osteosarcoma; Pharmacogenetics; Genetics; Chemotherapy;
Benefits and risks for the individual : anticoagulation for patients with atrial fibrillationHam H.A. van den, PhDLeufkens H.G.M., prof. dr.Klungel O.H., prof. dr.Staa T.J. van, prof. dr.Universiteit Utrecht (UU)2016Benefit-risk balance; Atrial fibrillation; Oral anticoagulants; Observational studies; Individuals;
End-organ damage in diabetes: exploring innovative targets and therapiesHamidi M., PhDHenning R.H., prof. dr.Buikema J.H., dr.Deelman L.E., dr.Rijksuniversiteit Groningen (RUG)2015Diabetes mellitus;
Cognition in Huntington's disease : the influence of motor behaviour and time Hart E.P. 't, PhDRoos R.A.C., prof. dr.Universiteit Leiden (UL)2013Huntington's disease; Cognition; Movement disorder; Executive functioning; Memory; P300; Motor behaviour
Improving the physical health of people with severe mental illness : the need for tailor made care and uniform evaluation of interventionsHasselt F.M. van, PhDLoonen A.J.M., prof. dr.Oud M.J.T., dr.Krabbe P.F.M., dr.Rijksuniversiteit Groningen (RUG)2013
Non-dispensing clinical pharmacists in general practice : training, implementation and clinical effectsHazen A.C.M., PhDBouvy M.L., prof. dr.Wit N.J. de, prof. dr.Bont A.A. de, prof. dr.Zwart D.L.M., dr.Universiteit Utrecht (UU)2018Clinical pharmacist; General practice; Medication reviews; Polypharmacy; Hospitalization; Professional identity;
Prediction and prevention of chronic renal impairment in high-risk populations; type 2 diabetes, hypertension & lung transplantationHellemons M.E., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Bakker S.J.L., prof. dr.Rijksuniversiteit Groningen (RUG)2012prediction and prevention of chronic renal impairment type 2 diabetes lung transplantation
Medication safety through information technology; a focus on medication prescribing and administering.Helmons P.J., PhDKosterink J.G.W., prof. dr.Daniels C.E., prof. dr.Rijksuniversiteit Groningen (RUG)2014medication safety information technology prescribing and administering drugs
Clinical decision support in community pharmacyHeringa M., PhDBouma H.R., PhDSmet P.A.G.M. de, prof. dr.Floor-Schreudering A., PhD PharmDUniversiteit Utrecht (UU)2017Patient safety; Clinical decision support system; Community pharmacy; Drug therapy;
The Clinical Pharmacology of performance enhancement and doping detection in sportsHeuberger J., dr.Cohen A.F., prof. dr.Groeneveld G.J., prof. dr.Rotmans J.I., dr.Universiteit Leiden (UL)2019Performance enhancement and doping detection in sports
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