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Displaying 1-50 of 270 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Diagnosis and treatment of obese children with insulin resistanceAa M.P. van der, PhDKnibbe C.A.J., prof. dr.Boer A. de, prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2016Obesity; Children; Insulin resistance; Metformin;
Continuity of pharmaceutical care for psychiatric patientsAbdullah-Koolmees H., PhDEgberts A.C.G., prof. dr.Heerdink E.R., dr.Gardarsdottir H., dr.Universiteit Utrecht (UU)2015Pharmaceutical care; Medication; Hospitalization; Somatic; Discharge; Discontinuation; Rehospitalization; Rehospitalization prediction;
Osteoporotic fractures: relation to mortality, medication use, and rheumatoid arthritisAbtahi S., PhDVries F. de, prof. dr.Boonen A.E.R.C.H., prof. dr.Driessen J.H.M., PhDBurden A.M., dr.Universiteit Maastricht (UM)2021
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantationAdmiraal R., PhDKnibbe C.A.J., prof. dr.Boelens J.J., dr.Bredius R.G.M., dr.Universiteit Leiden (UL)2017ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy;
Pain still hurts : pain assessment and pain management in intensive care patientsAhlers S.J.G.M., PhDTibboel D., prof. dr.Knibbe C.A.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2012Morphine; Remifentanil; Pain; Immune reconstitution; Intensive care; Critically ill; Analgesia; Anesthesiology; Pain assessment; Pain management;
Risk factors and treatment of paediatric chronic diseases - Type 1 diabetes, asthma and allergyAhmadizar F., PhDBoer A. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Children; Diabetes mellitus; Allergy
Revisiting co-trimoxazole for the treatment of tuberculosisAlsaad N.S.I., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis;
Challenging the cholinergic system: ageing, cognition & inflammationAlvarez-Jimenez R., PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Groeneveld G.J., prof. dr.Universiteit Leiden (UL)2017Neuropsychopharmacology Clinical Pharmacology Trials Cognition Dementia Cholinergis system Drug development
Integrated assessment of neurocognitive, neurophysiological and pain processing in early clinical drug developmentAmerongen G. van, PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Groeneveld G.J., prof. dr.Universiteit Leiden (UL)2020Clinical pharmacology Pharmacodynamics Pain Human pain models Cannabinoid GABA THC Multiple sclerosis (MS)
Preclinical targeting of the tumor microenvironment. Possibilities and consequencesArjaans M., PhDVries E.G.E. de, prof. dr.Schröder C.P., dr.Timmer-Bosscha H., dr.Rijksuniversiteit Groningen (RUG)2015
Regulatory benefit-risk assessment : different perspectivesArnardottir A.H., PhDHaaijer-Ruskamp F.M., prof. dr.Graeff P.A. de, prof. dr.Mol P.G.M., dr.Straus S.M.J.M., dr.Rijksuniversiteit Groningen (RUG)2013drug registration benefit risk
ADHD medication use and long-term consequencesBan E.F. van den, PhDEgberts A.C.G., prof. dr.Swaab-Barneveld J.T., prof. dr.Heerdink E.R., dr.Universiteit Utrecht (UU)2014ADHD medication use; Long-term consequences;
Improving acceptance of pharmacogenetic testing in clinical careBank P.C.D., PhD PharmDGuchelaar H.J., prof. dr.Swen J.J., PhDUniversiteit Leiden (UL)2018Pharmacogenetics, pharmacogenomics, primary care, Clinical-decision-support, drug-safety
Isoflurane induced eNOS signaling and cardioprotection: preconditioning mechanisms under normal and hyperglycemic conditionsBaotic I., PhDHenning R.H., prof. dr.Epema A.H., dr.Rijksuniversiteit Groningen (RUG)2018Isoflurane; eNOS; cardioprotection
Individualization of drug exposure in pediatric hematopoietic stem cell transplantationBartelink I.H., PhDEgberts A.C.G., prof. dr.Danhof M., prof. dr.Boelens J.J., dr.Knibbe C.A.J., prof. dr.Universiteit Utrecht (UU)2012Paediatrics; Busulfan; Hematopoietic stem cell transplantation;
Making things easier: how to improve antiviral drug treatment for childrenBastiaans D.E.T., dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2016Clinical pharmacology; Antiviral drug treatment;
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factorsBatenburg W.W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
DNA Damage-related Vascular Dysfunction: Pathways and InterventionsBautista-Niño P.K., PhDDanser A.H.J., prof. dr.Franco Duran O.H., Prof.dr.Roks A.J.M., dr.Ghanbari M., dr.Erasmus Universiteit Rotterdam (EUR)2017Cardiovascular disease; Vascular reactivity; DNA damage;
Neuropharmacology of novel dopamine modulators Beek E.T te, PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2014Dopamine Antagonist Drug development Pharmacokinetics Pharmacodynamics Schizophrenia Drug addiction Tachykinins
Information for rational drug prescribing to older patients : availability and applicabilityBeers E., PhDEgberts A.C.G., prof. dr.Leufkens H.G.M., prof. dr.Jansen P.A.F., dr.Universiteit Utrecht (UU)2014Drug prescribing; Older patients; Geriatrics; Medicines; Drug safety; Information; Aged;
Sustainable use of medication : medication waste and feasibility of redispensingBekker C.L., PhDEgberts A.C.G., prof. dr.Bouvy M.L., prof. dr.Bemt B.J.F. van den, dr.Gardarsdottir H., dr.Universiteit Utrecht (UU)2018Medication waste; UGT2B7; Unused medication; Redispensing; Pharmacy practice; Cost-benefit ratio;
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in childrenBellanti F., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2015Benefit-risk assessment; Paediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Albuminuria: more than a renal risk marker? Belt S.M. van den, PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Rijksuniversiteit Groningen (RUG)2018Albuminuria; Risk markers;
Challenges in using cardiovascular medications in Sub-Saharan AfricaBerhe D.F., PhDHaaijer-Ruskamp F.M., prof. dr.Taxis K., prof. dr.Mol P.G.M., dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Medication use; Cardiovascular disease;
Optimizing treatment with psychotropic agents through precision drug therapy: It is not about the meanBerm E.J.J., PhDWilffert B, prof. dr.Hak E., prof. dr.Maring J.G., dr.Rijksuniversiteit Groningen (RUG)2016Drug therapy; Psychotropic agents; Treatment individualization; Precision medicine;
Prediction and monitoring of chronic kidney diseaseBoele-Schutte E., PhDGansevoort R.T., prof. dr.Wolffenbuttel B.H.R., prof. dr.Lambers Heerspink H.J., prof. dr.Lutgers H.L., dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Prediction; Kidney disease;
Advanced vascular imaging : technical and clinical applications in type 2 diabetesBoer S.A. de, PhDKamphuisen T.P.W., prof. dr.Slart R.H.J.A., prof. dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; advanced vascular imaging; Diabetes mellitus;
Trials & tribulations : studies on the fate, transparency and efficiency of clinical drug trialsBogert C.A. van den, PhDLeufkens H.G.M., prof. dr.Souverein P.C., dr.Janssen S.W.J., dr.Universiteit Utrecht (UU)2017Clinical trials; Drug development; Publication bias; Regulatory science;
Linezolid in multidrug-resistant tuberculosisBolhuis M.S., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2015Tuberculosis; Linezolid;
Fluorescence-enhanced surgical navigation : towards tailored tumor detectionBoogerd L.S.F., PhDVelde C.J.H. Van de, Prof.dr.Burggraaf J., prof. dr.Vahrmeijer A.L., Dr.Universiteit Leiden (UL)2019Fluorescence guided surgery tailored tumor detection Intraoperative tumor imaging ICG CEA targeted tumor detection
Red wine polyphenols and vascular functionBotden I.P.G., PhDDanser A.H.J., prof. dr.Sijbrands E.J.G., prof. dr.Langendonk J.G., dr.Erasmus Universiteit Rotterdam (EUR)2012Antihypertensive drugs; Cardiovascular disease; Pharmacology;
Immunological aspects of hibernation as leads in the prevention of acute organ injury.Bouma H.R., PhDHenning R.H., prof. dr.Kroese F.G.M., prof. dr.Strijkstra A.M., dr.Rijksuniversiteit Groningen (RUG)2013hibernation acute organ injury immunological
Salt, acid, and the renin-angiotensin system in chronic kidney diseaseBovée D.M., PhDHoorn E.J., prof. dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2021Renin-angiotensin system; Kidney; Pharmacology;
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacologyBrake L.H.M. te, PHDBurger D.M., prof. dr.Russel F.G.M., prof. dr.Aarnoutse R.E., dr.Koenderink JB, dr. ir.Radboud Universiteit (RU)2016Tuberculosis; Clinical pharmacology;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgeryBrill M.J.E., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Rational prescribing in Europe: are future doctors well prepared?Brinkman D.J., PhDAgtmael M.A. van, prof. dr.Richir M.C., MD PhDTichelaar J., dr.Vrije Universiteit Amsterdam (VU)2018Clinical pharmacology; Pharmacotherapy; Prescribing;
Biomedical engineering for breathomics: towards clinical application in respitaroty diseases biomarker, instruments and Technology Readiness LevelsBrinkman P., PhDSterk P.J., prof. dr.Maitland-van der Zee A.H., prof. dr.Jongh F.H.C. de, dr.ir.Universiteit van Amsterdam (UvA)2019
Thermopharmacology of anticonvulsive treatment after perinatal asphyxiaBroek M.P.H. van den, PhDEgberts A.C.G., prof. dr.Rademaker C.M.A., dr.Universiteit Utrecht (UU)2013PK-PD modelling; Newborns; Thermopharmacology; Convulsions;
Unravelling the link between diabetes, insulin treatment and breast cancerBronsveld H.K., PhDBoer A. de, prof. dr.Bruin M.L. de, prof. dr.Schmidt M.K., dr. ir.Universiteit Utrecht (UU)2017Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment;
The road to tailor made azole antifungal therapyBrüggemann R.J.M., PhDBurger D.M., prof. dr.Verweij P.E., prof. dr.Blijlevens N.M.A., dr.Radboud Universiteit (RU)2011Antifungal; clinical pharmacology
First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and childrenBrussee J.M., PhDKnibbe C.A.J., prof. dr.Wildt S.N. de, prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2018Pharmacology; Pharmacokinetics; Paediatrics; Cytochrome P450; Drug metabolism; Midazolam; Population pharmacokinetics; Semi-PBPK modelling; CYP3A-mediated metabolism; First-pass metabolism;
How to scale clearance from adults to children for drugs undergoing hepatic metabolism? Insights from advanced PBPK modelling and simulationCalvier E.A.M., PhDKnibbe C.A.J., prof. dr.Tibboel D., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2018Paediatrics; Clearance; Allometric scaling; Hepatic metabolism; Physiologically based pharmacokinetics; Pharmacokinetics; Optimal design; Scaling clearance;
Clinical manifestations of sex hormonal influences in migraineCasteren D.S. van, PhDDanser A.H.J., prof. dr.Terwindt G.M., prof. dr.Maassen van den Brink A., dr.Universiteit Leiden (UL)2021Migraine; Clinical pharmacology; Treatment; Endocrinology; Pharmacology;
Cardiac aldosterone: origin and effectsChai W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Neurovascular pharmacology of prospective antimigraine drugsChan K.Y., PhDDanser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Migraine; Neurovascular pharmacology;
Human pharmacology of current and novel gaba(a)-ergic treatments for anxietyChen X., PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Jacobs G.E., dr.Universiteit Leiden (UL)2017Anxiety Human pharmacology GABA-ergic treatment
Exposure to antiretroviral agents in hiv-infected pregnant women: not too much-not too littleColbers E.P.H., PhDBurger D.M., prof. dr.Radboud Universiteit (RU)2015HIV; antiretroviral agents; clinical pharmacology; drug drug interactions
The role of glomerular filtration and active tubular secretion in predicting renal clearance of drugs in children using population pharmacokinetic and physiology-based pharmacokinetic modeling approaches: unspinning the yarnCristea S., PhDKnibbe C.A.J., prof. dr.Allegaert K., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2021Population PK; Optimise drug dosing; Paediatric renal clearance; PBPK; Paediatrics; Renal clearance; Population pharmacokinetics; Physiologically based pharmacokinetics; Maturation; Active tubular secretion; Renal transporters;
New insights into the role of breast cancer resistance protein in endocrine and metabolic processesDankers A.C.A., PhDRussel F.G.M., prof. dr.Sweep C.G.J., prof. dr.Masereeuw R., prof. dr.Radboud Universiteit (RU)2014Cancer; Breast cancer;
A quest to optimize the clinical pharmacology of tuberculosis and human immunodeficiency virus drug treatmentDaskapan A., PhDWerf T.S. van der, prof. dr.Alffenaar J.W.C., prof. dr.Stienstra Y., prof. dr.Rijksuniversiteit Groningen (RUG)2018Tuberculosis; Immunodeficiency virus drug treatment
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