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Displaying 51-100 of 278 results.

Titel	Promovendus	Promotor 1	Promotor 2	Copromotor 1	Universiteit	Promotiejaar	Trefwoorden

Cardiac aldosterone: origin and effects	Chai W., dr.	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2005	Cardiovascular disease; Pharmacology;
Assessment of ischaemia and reperfusion injury	Wouters C.W., PhD	Rongen G.A., prof. dr.	Oyen W.J.G., prof. dr.		Radboud Universiteit (RU)	2013	Ischemia/reperfusion injury; adenosine; atorvastatin; forearm;
Aortic pathology and the role of the renin-angiotensin system	Molzer E., PhD	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2011	Pharmacology; Cardiovascular disease; Renin-angiotensin system;
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factors	Batenburg W.W., dr.	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2005	Cardiovascular disease; Pharmacology;
An orchestra in need of a conductor challenges and opportunities in multi-infusion therapy	Doesburg F		Touw D.J., prof. dr.		Rijksuniversiteit Groningen (RUG)	2021	multi-infusion therapy
Albuminuria: more than a renal risk marker?	Belt S.M. van den, PhD	Zeeuw D. de, prof. dr.	Lambers Heerspink H.J., prof. dr.		Rijksuniversiteit Groningen (RUG)	2018	Albuminuria; Risk markers;
Advanced vascular imaging : technical and clinical applications in type 2 diabetes	Boer S.A. de, PhD	Kamphuisen T.P.W., prof. dr.	Slart R.H.J.A., prof. dr.		Rijksuniversiteit Groningen (RUG)	2017	Pharmacology; advanced vascular imaging; Diabetes mellitus;
(Pro)renin revisited: new insights from studies in mast cells	Krop M., dr.	Danser A.H.J., prof. dr.			Erasmus Universiteit Rotterdam (EUR)	2009	Cardiovascular disease; Pharmacology; Prorenin;
	Suurs F	Vries E.G.E. de, prof. dr.	Lub-de Hooge M.N., dr.		Rijksuniversiteit Groningen (RUG)	2021	Molecular imaging of immunotherapy biodistribution and the tumor immune environment
Building a clinical pharmacology framework for the safe and effective use of antifungal agents	Lempers VJC	Burger D.M., prof. dr.	Brüggemann R.J.M., PhD	Aarnoutse R.E., dr.	Radboud Universiteit (RU)	2016	Antifungal drugs; Clinical pharmacology;
The influence of the sample matrix on LC-MS/MS method development and analytical performance	Koster R.A., PhD	Uges D.R.A., prof. dr.	Kosterink J.G.W., prof. dr.	Alffenaar J.W.C., prof. dr.	Rijksuniversiteit Groningen (RUG)	2015
Revisiting co-trimoxazole for the treatment of tuberculosis	Alsaad N.S.I., PhD	Kosterink J.G.W., prof. dr.	Werf T.S. van der, prof. dr.	Alffenaar J.W.C., prof. dr.	Rijksuniversiteit Groningen (RUG)	2016	Tuberculosis;
Exploring strategies to individualize treatment with aminoglycosides and co-trimoxazole for MDR Tuberculosis	Dijkstra J.A., PhD	Werf T.S. van der, prof. dr.	Kosterink J.G.W., prof. dr.	Alffenaar J.W.C., prof. dr.	Rijksuniversiteit Groningen (RUG)	2017	Personalized medicine; Tuberculosis;
Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children	De Cock R.F.W., PhD	Knibbe C.A.J., prof. dr.	Danhof M., prof. dr.	Allegaert K., prof. dr.	Universiteit Leiden (UL)	2014	Paediatrics; Population PK; Aminoglycosides; Propylene glycol; GFR; Renal function; Antibiotics; Glomerular filtration; Developmental changes; Pharmacokinetics; Newborns;
Drug-related problems: risk factors and the role of clinical pharmacists	Zaal R.J., PhD	Vulto A.G., prof. dr.	Haaijer-Ruskamp F.M., prof. dr.	Bemt P.M.L.A. van den, dr.	Erasmus Universiteit Rotterdam (EUR)	2016	Drug-related problems; Risk factors;
Implementing dried spot sampling in transplant patient care	Veenhof H.	Touw D.J., prof. dr.	Bakker S.J.L., prof. dr.	Berger S.P., prof. dr.	Rijksuniversiteit Groningen (RUG)	2020	dried blood spot; Transplantation;
Precision anticoagulation with vitamin K antagonists in children	Maagdenberg H., PhD	Boer A. de, prof. dr.	Maitland-van der Zee A.H., prof. dr.	Bierings M.B., dr.	Universiteit Utrecht (UU)	2018	Anticoagulation; Thrombosis; Bleedings; Children; Adolescents; Pharmacogenetics; Acenocoumarol; Phenprocoumon; Personalized medicine; Medicines;
The road to tailor made azole antifungal therapy	Brüggemann R.J.M., PhD	Burger D.M., prof. dr.	Verweij P.E., prof. dr.	Blijlevens N.M.A., dr.	Radboud Universiteit (RU)	2011	Antifungal; clinical pharmacology
Cardiovascular molecular imaging	Haas H.J. de, PhD	Dierckx R.A.J.O., prof. dr.	Slart R.H.J.A., prof. dr.	Boersma H.H., dr.	Rijksuniversiteit Groningen (RUG)	2018	Pharmacology; Cardiovascular molecular imaging
The role of endogenous H2S production during hybernation and forced hypothermia: towards safe cooling and rewarming in clinical practice	Dugbartey G.J., PhD	Henning R.H., prof. dr.		Bouma H.R., PhD	Rijksuniversiteit Groningen (RUG)	2015
Reversible suppression of hemostasis in hibernation and hypothermia	Vrij E.L. de	Henning R.H., prof. dr.		Bouma H.R., PhD	Rijksuniversiteit Groningen (RUG)	2019	Hypothermia; Hibernation;
Mitochondrial failure in sepsis; Acute mechnisms and long-term consequences.	Henning R.H., prof. dr.			Bouma H.R., PhD	Rijksuniversiteit Groningen (RUG)	0	Mitrochondrial failure in Sepsis
Medication safety in Vietnamese hospital: a focus on medication errors and safety culture	Nguyen T.H., PhD	Taxis K., prof. dr.	Haaijer-Ruskamp F.M., prof. dr.	Brouwers J.R.B.J., prof. dr.	Rijksuniversiteit Groningen (RUG)	2014
Antifungal pharmacokinetics in the era of the obesity pandemic	Wasmann R.E., PhD	Burger D.M., prof. dr.	Knibbe C.A.J., prof. dr.	Brüggemann R.J.M., PhD	Radboud Universiteit (RU)	2019	Antifungal drugs; Clinical pharmacology; Morbid obesity; Micafungin; Anidulafungin; Posaconazole; Liposomal amphotericinB;
Acute and chronic pain after cardiac surgery	Gulik L. van, PhD	Knibbe C.A.J., prof. dr.	Tibboel D., prof. dr.	Bruins P., dr.	Universiteit Leiden (UL)	2014	Acute pain; Intensive Care Unit; Chronic pain; Cardiac surgery; Pain management;
Targeting proteostasis in atrial fibrillation	Zhang D., PhD	Henning R.H., prof. dr.		Brundel B.J.J.M., dr.	Rijksuniversiteit Groningen (RUG)	2015	Atrial fibrillation; Modelling-&-simulations;
Loss of proteostasis as a substrate for Atrial Fibrilation.	Meijering R.A.M., PhD	Henning R.H., prof. dr.		Brundel B.J.J.M., dr.	Rijksuniversiteit Groningen (RUG)	2014	Atrial fibrillation; Proteostasis;
Implications of the cardiomyocyte stress response on protein homeostasis in atrial fibrillation	Wiersma M., PhD	Henning R.H., prof. dr.		Brundel B.J.J.M., dr.	Rijksuniversiteit Groningen (RUG)	2016	Atrial fibrillation;
Exploring the role of glucagon in glucose homeostasis	Dongen M.G.J. van, PhD	Cohen A.F., prof. dr.	Romijn J.A., prof dr	Burggraaf J., prof. dr.	Universiteit Leiden (UL)	2015	Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
Treatment optimization of fluoropyrimidines as single agent and in combination therapy	Deenen M.J., PhD	Schellens J.H.M., prof. dr.	Beijnen J.H., prof. dr.	Cats A., dr.	Universiteit Utrecht (UU)	2011	Pharmacogenetics; Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Dihydropyrimidine dehydrogenase; DPD-deficiency;
The role of differentiation factor 15 in diabetic kidney injury	Mazagová M., PhD	Henning R.H., prof. dr.		Deelman L.E., dr.	Rijksuniversiteit Groningen (RUG)	2012	Diabetic kidney disease; Growth differentiation factor 15;
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in children	Bellanti F., PhD	Danhof M., prof. dr.		Della Pasqua O.E., dr.	Universiteit Leiden (UL)	2015	Benefit-risk assessment; Paediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Adherence to antiretroviral combination therapy in children : what a difference half a day makes...	Piana C., PhD	Danhof M., prof. dr.		Della Pasqua O.E., dr.	Universiteit Leiden (UL)	2013	Paediatrics; Antiretroviral combination therapy; Compliance; Antiretroviral drugs; Paediatric populations; Drug combinations; Model-based; Covariate analysis; Predictive pharmacokinetic models; Clinical trial simulations; Adherence; Forgiveness of non-adherence;
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safety	Noorsyahdy A.Y., MD PhD	Boer A. de, prof. dr.	Klungel O.H., prof. dr.	Deneer V.H.M., dr.	Universiteit Utrecht (UU)	2017	Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics;
Driving-impairing medicines and traffic safety: patients' perspectives	Monteiro S.P., PhD	Gier J.J. de, prof. dr.		Dijk C.E.M.J. van, dr. ir.	Rijksuniversiteit Groningen (RUG)	2014
Introducing Clinical Pharmacology to Hepatitis C Therapy	Kanter C.T.M.M. de, PhD	Burger D.M., prof. dr.	Drenth J.P.H., prof. dr.	Dofferhoff A.S.M., dr.	Radboud Universiteit (RU)	2015	Hepatitis C; Clinical Pharmacology; Therapeutic drug monitoring; drug drug interactions
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasis	Kip A.E., PhD	Beijnen J.H., prof. dr.	Schellens J.H.M., prof. dr.	Dorlo T.P.C., dr.	Universiteit Utrecht (UU)	2017	Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin;
Isoflurane induced eNOS signaling and cardioprotection: preconditioning mechanisms under normal and hyperglycemic conditions	Baotic I., PhD	Henning R.H., prof. dr.		Epema A.H., dr.	Rijksuniversiteit Groningen (RUG)	2018	Isoflurane; eNOS; cardioprotection
Clinical decision support in community pharmacy	Heringa M., PhD	Bouma H.R., PhD	Smet P.A.G.M. de, prof. dr.	Floor-Schreudering A., PhD PharmD	Universiteit Utrecht (UU)	2017	Patient safety; Clinical decision support system; Community pharmacy; Drug therapy;
Biomarkers in real-life COPD management	Oshagbemi O.A., PhD	Wouters E.F.M., prof. dr.	Vries F. de, prof. dr.	Franssen F.M.E., dr.	Universiteit Maastricht (UM)	2019
Harmonising relative effectiveness assessments of medicines in Europe	Kleijnen S., PhD	Boer A. de, prof. dr.	Leufkens H.G.M., prof. dr.	Goettsch W.G., dr.	Universiteit Utrecht (UU)	2016	Medicines; Relative effectiveness; Reimbursement; Harmonisation; Europe; Methods; Health technology assessment (HTA);
Integrated pharmaceutical care: cooperation between pharmacist, general practioner, and patient and the development of a pharmaceutical care plan	Geurts M.M.E., PhD	Gier J.J. de, prof. dr.	Brouwers J.R.B.J., prof. dr.	Graeff P.A. de, prof. dr.	Rijksuniversiteit Groningen (RUG)	2015
Measuring pharmacodynamics in early clinical drug studies in multiple sclerosis	Kanhai K.M.S	Cohen A.F., prof. dr.		Groeneveld G.J., prof. dr.	Universiteit Leiden (UL)	2019	Multiple sclerosis Drug development Biomarkers Remyelination
Integrated assessment of neurocognitive, neurophysiological and pain processing in early clinical drug development	Amerongen G. van, PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Groeneveld G.J., prof. dr.	Universiteit Leiden (UL)	2020	Clinical pharmacology Pharmacodynamics Pain Human pain models Cannabinoid GABA THC Multiple sclerosis (MS)
Clinical pharmacological aspects of mitochondrial function in muscle	Diemen M.P.J. van, PhD	Cohen A.F., prof. dr.	Nelissen R.G.H.H., prof. dr.	Groeneveld G.J., prof. dr.	Universiteit Leiden (UL)	2021	Clinical pharmacology; Huntington's disease; Mitochondrial function; Magnetic Resonance Spectroscopy; Sarcopenia; Phosphocreatine recovery rate; Knee; Total knee arthroplasty; Wearables; Peripheral blood mononuclear cells; Protoporphorin IX Triple State Lifetime techn;
Challenging the cholinergic system: ageing, cognition & inflammation	Alvarez-Jimenez R., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Groeneveld G.J., prof. dr.	Universiteit Leiden (UL)	2017	Neuropsychopharmacology Clinical Pharmacology Trials Cognition Dementia Cholinergis system Drug development
Monitoring patients using psychotropic drugs	Nederlof M., PhD	Egberts A.C.G., prof. dr.		Heerdink E.R., dr.	Universiteit Utrecht (UU)	2018	Therapeutic drug monitoring; Biomarkers; Benefit-risk assessment; Psychotropic drugs; Psychiatry; Antidepressants; Antipsychotics
ADHD medication use and long-term consequences	Ban E.F. van den, PhD	Egberts A.C.G., prof. dr.	Swaab-Barneveld J.T., prof. dr.	Heerdink E.R., dr.	Universiteit Utrecht (UU)	2014	ADHD medication use; Long-term consequences;
The Renin-Angiotensin System in Hypertension and Diabetes: From Man to Rodent and Back	Roksnoer L.C.W.	Danser A.H.J., prof. dr.	Zietse R., prof.dr.	Hoorn E.J., prof. dr.	Erasmus Universiteit Rotterdam (EUR)	2016	Renin-angiotensin system; Renal function; Hypertension; Diabetic kidney disease;
Human pharmacology of current and novel gaba(a)-ergic treatments for anxiety	Chen X., PhD	Gerven J.M.A. van, prof. dr.	Cohen A.F., prof. dr.	Jacobs G.E., dr.	Universiteit Leiden (UL)	2017	Anxiety Human pharmacology GABA-ergic treatment