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Displaying 51-100 of 270 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Patient compliance with drug storage recommendationsVlieland N.D., PhDEgberts A.C.G., prof. dr.Bouvy M.L., prof. dr.Gardarsdottir H., dr.Bemt B.J.F. van den, dr.Universiteit Utrecht (UU)2018Drug storage; Temperature conditions; Biologic drugs; Biologicals; Tumor necrosis factor-alpha inhibitors; Oral anticancer drugs; Immunogenicity; Pharmaceutical supply chain; Quality; Personality traits; Aggregation;
Monitoring patients using clozapineMan W.H., PhDEgberts A.C.G., prof. dr.Solinge W.W. van, prof. dr.Wilting I., dr.Heerdink E.R., dr.Universiteit Utrecht (UU)2018Biomarkers; Adherence; Monitoring; Sialorrhea; Inflammation; Glycopyrrolate; Schizophrenia; Antipsychotics; Pharmacovigilance;
Antipsychotics, delirium and glucose in older patientsKeulen K. van, PhDEgberts A.C.G., prof. dr.Knol W., PhDHeerdink E.R., dr.Universiteit Utrecht (UU)2018Antipsychotics; Older patients; Delirium; Hypoglycemia; Hyperglycemia; Incapacitated patients; Glucose variability;
Pharmacological approaches to optimize TB treatmentZuur M.A.Alffenaar J.W.C., prof. dr.Werf T.S. van der, prof. dr.Rijksuniversiteit Groningen (RUG)2018Optimize; Tuberculosis; Treatment;
Non-dispensing clinical pharmacists in general practice : training, implementation and clinical effectsHazen A.C.M., PhDBouvy M.L., prof. dr.Wit N.J. de, prof. dr.Bont A.A. de, prof. dr.Zwart D.L.M., dr.Universiteit Utrecht (UU)2018Clinical pharmacist; General practice; Medication reviews; Polypharmacy; Hospitalization; Professional identity;
Improving acceptance of pharmacogenetic testing in clinical careBank P.C.D., PhD PharmDGuchelaar H.J., prof. dr.Swen J.J., PhDUniversiteit Leiden (UL)2018Pharmacogenetics, pharmacogenomics, primary care, Clinical-decision-support, drug-safety
Sex hormones and cardiometabolic riskGlisic M., PhDDanser A.H.J., prof. dr.Franco Duran O.H., Prof.dr.Roks A.J.M., dr.Erasmus Universiteit Rotterdam (EUR)2018Epidemiology; Pharmacology; Risk factors; Sex hormonesCardiovascular disease; Metabolism;
Precision anticoagulation with vitamin K antagonists in childrenMaagdenberg H., PhDBoer A. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Bierings M.B., dr.Universiteit Utrecht (UU)2018Anticoagulation; Thrombosis; Bleedings; Children; Adolescents; Pharmacogenetics; Acenocoumarol; Phenprocoumon; Personalized medicine; Medicines;
Sustainable use of medication : medication waste and feasibility of redispensingBekker C.L., PhDEgberts A.C.G., prof. dr.Bouvy M.L., prof. dr.Bemt B.J.F. van den, dr.Gardarsdottir H., dr.Universiteit Utrecht (UU)2018Medication waste; UGT2B7; Unused medication; Redispensing; Pharmacy practice; Cost-benefit ratio;
Therapeutic drug monitoring: how to improve moxifloxacin exposure in tuberculosis patientsPranger A.Kosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Rijksuniversiteit Groningen (RUG)2018drug monitoring moxifloxacin exposure tuberculosis
A quest to optimize the clinical pharmacology of tuberculosis and human immunodeficiency virus drug treatmentDaskapan A., PhDWerf T.S. van der, prof. dr.Alffenaar J.W.C., prof. dr.Stienstra Y., prof. dr.Rijksuniversiteit Groningen (RUG)2018Tuberculosis; Immunodeficiency virus drug treatment
Isoflurane induced eNOS signaling and cardioprotection: preconditioning mechanisms under normal and hyperglycemic conditionsBaotic I., PhDHenning R.H., prof. dr.Epema A.H., dr.Rijksuniversiteit Groningen (RUG)2018Isoflurane; eNOS; cardioprotection
Future drugs in atherosclerotic cardiovascular diseasePoelgeest E.P vanBurggraaf J., prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2018Atherosclerosis Systemic inflammation Hypercholesterolemia PCSK9 inhibitor TLR4 sinaling Acute kidney injury Endothelial dysfunction Human endotoxemia model Ex vivo LPS challenge test Invivo LPS challenge test
Fluorescence-guided cancer surgery:clinical translation of tumor targeted agentsHoogstins C.E.SBurggraaf J., prof. dr.Cohen A.F., prof. dr.Vahrmeijer A.L., Dr.Universiteit Leiden (UL)2018Image-guided surgery Fluorescence Tumor targeted Oncological surgery
The use of a battery of evoked pain models in early phase drug developmentOkkerse P.Cohen A.F., prof. dr.Groeneveld G.J., prof. dr.Universiteit Leiden (UL)2018Pain Human pain models Analgesics Clinical pharmacology Pharmacodynamics Drug Development
Sticky & Dirty Proteins- or on the poorly characterised, peculiar, pharmacokinetic and immunostimulatory aspects of biopharmaceuticalsReijers J.A.A.Burggraaf J., prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2018Biopharmaeuticals Biologics Clinical Pharmacology Pharmacokinetics Adverse immunostimulation Immunotoxicity Drug impurity Drug contamination Monoclonal antibody
First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and childrenBrussee J.M., PhDKnibbe C.A.J., prof. dr.Wildt S.N. de, prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2018Pharmacology; Pharmacokinetics; Paediatrics; Cytochrome P450; Drug metabolism; Midazolam; Population pharmacokinetics; Semi-PBPK modelling; CYP3A-mediated metabolism; First-pass metabolism;
How to scale clearance from adults to children for drugs undergoing hepatic metabolism? Insights from advanced PBPK modelling and simulationCalvier E.A.M., PhDKnibbe C.A.J., prof. dr.Tibboel D., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2018Paediatrics; Clearance; Allometric scaling; Hepatic metabolism; Physiologically based pharmacokinetics; Pharmacokinetics; Optimal design; Scaling clearance;
Pharmaceutical development, preclinical research and clinical application of the bone-targeting therapeutic radiopharmaceutical rhenium-188-HEDPLange R., PhDHendrikse N.H., prof. dr.Heine R. ter, dr.Bloemendal H.J., dr.Vrije Universiteit Amsterdam (VU)2017Radiopharmaceutics; Pharmaceutical development; Rhenium;
Unintended effects of anti-hyperglycaemic drugs studied in population-based cohortsDriessen J.H.M., PhDBergh J.P.W. van den, prof. dr.Vries F. de, prof. dr.Onzenoort H.A.W. van, PhDUniversiteit Maastricht (UM)2017Hyperglycaemic drugs; Population-based;
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantationAdmiraal R., PhDKnibbe C.A.J., prof. dr.Boelens J.J., dr.Bredius R.G.M., dr.Universiteit Leiden (UL)2017ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy;
ColoPulse tablets in inflammatory bowel disease: formulation, potential application and evaluationMaurer J.M., PhDKosterink J.G.W., prof. dr.Frijlink H.W., prof. dr.Woerdenbag H.J., dr.Rijksuniversiteit Groningen (RUG)2017ColoPulse tablets; Inflammatory bowel disease;
Exploring optimal pharmacotherapy after bariatic surgery: where two worlds meetYska J.P., PhDRoon E.N. van, prof. dr.Wilffert B, prof. dr.Rijksuniversiteit Groningen (RUG)2017Optimal pharmacotherapy; Bariatric surgery;
Variability in drug response: personalized diabetes carePetrykiv S.I.Lambers Heerspink H.J., prof. dr.Zeeuw D. de, prof. dr.Laverman G.D., dr.Rijksuniversiteit Groningen (RUG)2017
Techniques to improve neurological outcome after cardiac surgeryKok W.F., PhDHenning R.H., prof. dr.Absalom A.R., prof. dr.Scheeren T.W.L., prof. dr.Rijksuniversiteit Groningen (RUG)2017Cardiac surgery; Clinical pharmacology; Neurological outcome;
Towards better fall prevention - examining the interplay between factors that influence gait in older patientsGroot M.H. de, PhDBeijnen J.H., prof. dr.Lamoth C.J.C., dr.Universiteit Utrecht (UU)2017Falls; Gait analysis; Accelerometry; Frailty; Osteoporosis; Maturation; Medication use; Medication use; Geriatrics; Older patients;
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasisKip A.E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Dorlo T.P.C., dr.Universiteit Utrecht (UU)2017Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin;
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safetyNoorsyahdy A.Y., MD PhDBoer A. de, prof. dr.Klungel O.H., prof. dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2017Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics;
Solid dispersions in oncology: a solution to solubility-limited oral drug absorptionSawicki E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2017Solid dispersions; Pharmacokinetics; Spray drying; Freeze drying; Docetaxel; Paclitaxel; Elacridar;
Paving ways for personalizing drug therapy during pregnancyDaud N.A.A., PhDWilffert B, prof. dr.Kammen-Bergman J.E.H. van, dr.Rijksuniversiteit Groningen (RUG)2017Personalized medicine; Drug therapy; Pregnancy;
Multimodality ImAging of Cardiovascular Dysfunction: Risk factors, diagnostics and treatment optionsThiel B.S. van, PhDKanaar R., prof. dr.Danser A.H.J., prof. dr.Essers J., dr.Pluijm I. van der, dr.Erasmus Universiteit Rotterdam (EUR)2017Cardiovascular disease; Imaging; Aging; Risk factors; Diagnostics; Treatment options
Unravelling the link between diabetes, insulin treatment and breast cancerBronsveld H.K., PhDBoer A. de, prof. dr.Bruin M.L. de, prof. dr.Schmidt M.K., dr. ir.Universiteit Utrecht (UU)2017Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment;
Pharmacogenetics of sunitinib in metastatic renal cell carcinomaDiekstra M.H.M., drGuchelaar H.J., prof. dr.Swen J.J., PhDUniversiteit Leiden (UL)2017Genetics; Pharmacogenetics; Renal function;
Renin-Synthesizing Cells and BeyondGoes Martini A., PhDDanser A.H.J., prof. dr.Neves F.A.R., prof. dr.Erasmus Universiteit Rotterdam (EUR)2017Renin-angiotensin system; Renal function;
Multimodality ImAging of Cardiovascular Dysfunction: Risk Factors, Diagnostics and Treatment OptionsThiel B.S. van, PhDKanaar R., prof. dr.Danser A.H.J., prof. dr.Essers J., dr.Pluijm I. van der, dr.Erasmus Universiteit Rotterdam (EUR)2017Cardiovascular disease; Risk factors; Treatment options;
DNA Damage-related Vascular Dysfunction: Pathways and InterventionsBautista-Niño P.K., PhDDanser A.H.J., prof. dr.Franco Duran O.H., Prof.dr.Roks A.J.M., dr.Ghanbari M., dr.Erasmus Universiteit Rotterdam (EUR)2017Cardiovascular disease; Vascular reactivity; DNA damage;
Challenges in using cardiovascular medications in Sub-Saharan AfricaBerhe D.F., PhDHaaijer-Ruskamp F.M., prof. dr.Taxis K., prof. dr.Mol P.G.M., dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Medication use; Cardiovascular disease;
Evaluation of renal end points in nephrology trials. Weldegiorgis MLambers Heerspink H.J., prof. dr.Zeeuw D. de, prof. dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Nephrology trials; renal endpoints
Exploring strategies to individualize treatment with aminoglycosides and co-trimoxazole for MDR TuberculosisDijkstra J.A., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Alffenaar J.W.C., prof. dr.Rijksuniversiteit Groningen (RUG)2017Personalized medicine; Tuberculosis;
Prediction and monitoring of chronic kidney diseaseBoele-Schutte E., PhDGansevoort R.T., prof. dr.Wolffenbuttel B.H.R., prof. dr.Lambers Heerspink H.J., prof. dr.Lutgers H.L., dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Prediction; Kidney disease;
Advanced vascular imaging : technical and clinical applications in type 2 diabetesBoer S.A. de, PhDKamphuisen T.P.W., prof. dr.Slart R.H.J.A., prof. dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; advanced vascular imaging; Diabetes mellitus;
Preclinical molecular imaging of target expression and target dynamics in cancer. Pool M., PhDVries E.G.E. de, prof. dr.Lub-de Hooge M.N., dr.Terwisscha van Scheltinga A.G.T., PhDRijksuniversiteit Groningen (RUG)2017
Towards understanding interchangeability of generic drugsYu Y, drNeef C., prof. dr.Burger D.M., prof. dr.Universiteit Maastricht (UM)2017
Assessing the impact of gout:validating and understanding outcomesSpaetgens B.P.A., drBoonen A.E.R.C.H., prof. dr.Vries F. de, prof. dr.Universiteit Maastricht (UM)2017
Pharmacy Preparations: European quality standards and regulationScheepers H., drNeef C., prof. dr.Universiteit Maastricht (UM)2017Pharmacy policy;
Trials & tribulations : studies on the fate, transparency and efficiency of clinical drug trialsBogert C.A. van den, PhDLeufkens H.G.M., prof. dr.Souverein P.C., dr.Janssen S.W.J., dr.Universiteit Utrecht (UU)2017Clinical trials; Drug development; Publication bias; Regulatory science;
Readmission to primary care : the role of community pharmacists post-dischargeEnsing H.T., PhDBouvy M.L., prof. dr.Koster E.S., PhDDooren A.A. van, dr.Universiteit Utrecht (UU)2017Safety; Care continuity; Discharge; Pharmacist home visit;
Clinical decision support in community pharmacyHeringa M., PhDBouma H.R., PhDSmet P.A.G.M. de, prof. dr.Floor-Schreudering A., PhD PharmDUniversiteit Utrecht (UU)2017Patient safety; Clinical decision support system; Community pharmacy; Drug therapy;
Priority medicines for children : exploring age-appropriate medicines and antibiotic use in childrenIvanovska V., PhDLeufkens H.G.M., prof. dr.Mantel-Teeuwisse A.K., dr.Dijk C.E.M.J. van, dr. ir.Universiteit Utrecht (UU)2017Paediatric pharmacotherapy; Paediatric drug development; Priority setting; Age-appropriate formulations; Antibiotic use; Children;
The pursuit of user-friendly medicines : older people in the hot seatNotenboom K., PhDBouvy M.L., prof. dr.Leufkens H.G.M., prof. dr.Universiteit Utrecht (UU)2017Usability; User-friendly; Older patients; Elderly; Medicines; Medication use; Medication errors; Tablet breaking; Swallowing; Medication packaging;
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