Overzicht Proefschriften
Tips in using the search/filter fieldsDisplaying 51-100 of 278 results.
Titel | Promovendus | Promotor 1 | Promotor 2 | Copromotor 1 | Copromotor 2 | Universiteit | Promotiejaar | Trefwoorden |
---|---|---|---|---|---|---|---|---|
Endothelial dysfunction in cardiovascular disease | Heuvel M. van den, PhD | Duncker D.J.G.M., Prof.dr. | Danser A.H.J., prof. dr. | Erasmus Universiteit Rotterdam (EUR) | 2018 | Cardiovascular disease; Vascular reactivity; Cholesterol; | ||
Medication optimisation : methodological aspects and new strategies | Mestres Gonzalvo C., PhD | Verhey F.R., prof.dr. | Kuy P.H.M. van der, dr. | Janknegt R., PharmD PhD | Universiteit Maastricht (UM) | 2018 | Elderly; Geriatrics; Hospital pharmacists; Medication use; Model-based; Model validation; Older patients; Optimal pharmacotherapy; Pharmaceutical care; Pharmacotherapy; Pharmacovigilance; | |
Quality of presribing in chronic kidney disease and type 2 diabetes. | Smits K.P.J. | Denig P., prof. dr. | Muro E.P., PhD | Sidorenkov G., PhD | Rijksuniversiteit Groningen (RUG) | 2018 | Pharmacology; Prescribing; Chronic kidney disease; | |
Cardiovascular molecular imaging | Haas H.J. de, PhD | Dierckx R.A.J.O., prof. dr. | Slart R.H.J.A., prof. dr. | Boersma H.H., dr. | Rijksuniversiteit Groningen (RUG) | 2018 | Pharmacology; Cardiovascular molecular imaging | |
Albuminuria: more than a renal risk marker? | Belt S.M. van den, PhD | Zeeuw D. de, prof. dr. | Lambers Heerspink H.J., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2018 | Albuminuria; Risk markers; | ||
Preclinical molecular imgaging to study the biodistribution of antibody derivatives in oncology. | Warnders J.F., PhD | Kosterink J.G.W., prof. dr. | Vries E.G.E. de, prof. dr. | Lub-de Hooge M.N., dr. | Rijksuniversiteit Groningen (RUG) | 2018 | preclinical molecular imaging; oncology | |
Monitoring patients using psychotropic drugs | Nederlof M., PhD | Egberts A.C.G., prof. dr. | Heerdink E.R., dr. | Universiteit Utrecht (UU) | 2018 | Therapeutic drug monitoring; Biomarkers; Benefit-risk assessment; Psychotropic drugs; Psychiatry; Antidepressants; Antipsychotics | ||
Patient compliance with drug storage recommendations | Vlieland N.D., PhD | Egberts A.C.G., prof. dr. | Bouvy M.L., prof. dr. | Gardarsdottir H., dr. | Bemt B.J.F. van den, dr. | Universiteit Utrecht (UU) | 2018 | Drug storage; Temperature conditions; Biologic drugs; Biologicals; Tumor necrosis factor-alpha inhibitors; Oral anticancer drugs; Immunogenicity; Pharmaceutical supply chain; Quality; Personality traits; Aggregation; |
Monitoring patients using clozapine | Man W.H., PhD | Egberts A.C.G., prof. dr. | Solinge W.W. van, prof. dr. | Wilting I., dr. | Heerdink E.R., dr. | Universiteit Utrecht (UU) | 2018 | Biomarkers; Adherence; Monitoring; Sialorrhea; Inflammation; Glycopyrrolate; Schizophrenia; Antipsychotics; Pharmacovigilance; |
Antipsychotics, delirium and glucose in older patients | Keulen K. van, PhD | Egberts A.C.G., prof. dr. | Knol W., PhD | Heerdink E.R., dr. | Universiteit Utrecht (UU) | 2018 | Antipsychotics; Older patients; Delirium; Hypoglycemia; Hyperglycemia; Incapacitated patients; Glucose variability; | |
Pharmacological approaches to optimize TB treatment | Zuur M.A. | Alffenaar J.W.C., prof. dr. | Werf T.S. van der, prof. dr. | Rijksuniversiteit Groningen (RUG) | 2018 | Optimize; Tuberculosis; Treatment; | ||
Non-dispensing clinical pharmacists in general practice : training, implementation and clinical effects | Hazen A.C.M., PhD | Bouvy M.L., prof. dr. | Wit N.J. de, prof. dr. | Bont A.A. de, prof. dr. | Zwart D.L.M., dr. | Universiteit Utrecht (UU) | 2018 | Clinical pharmacist; General practice; Medication reviews; Polypharmacy; Hospitalization; Professional identity; |
Improving acceptance of pharmacogenetic testing in clinical care | Bank P.C.D., PhD PharmD | Guchelaar H.J., prof. dr. | Swen J.J., PhD | Universiteit Leiden (UL) | 2018 | Pharmacogenetics, pharmacogenomics, primary care, Clinical-decision-support, drug-safety | ||
Sex hormones and cardiometabolic risk | Glisic M., PhD | Danser A.H.J., prof. dr. | Franco Duran O.H., Prof.dr. | Roks A.J.M., dr. | Erasmus Universiteit Rotterdam (EUR) | 2018 | Epidemiology; Pharmacology; Risk factors; Sex hormonesCardiovascular disease; Metabolism; | |
Precision anticoagulation with vitamin K antagonists in children | Maagdenberg H., PhD | Boer A. de, prof. dr. | Maitland-van der Zee A.H., prof. dr. | Bierings M.B., dr. | Universiteit Utrecht (UU) | 2018 | Anticoagulation; Thrombosis; Bleedings; Children; Adolescents; Pharmacogenetics; Acenocoumarol; Phenprocoumon; Personalized medicine; Medicines; | |
Sustainable use of medication : medication waste and feasibility of redispensing | Bekker C.L., PhD | Egberts A.C.G., prof. dr. | Bouvy M.L., prof. dr. | Bemt B.J.F. van den, dr. | Gardarsdottir H., dr. | Universiteit Utrecht (UU) | 2018 | Medication waste; UGT2B7; Unused medication; Redispensing; Pharmacy practice; Cost-benefit ratio; |
Therapeutic drug monitoring: how to improve moxifloxacin exposure in tuberculosis patients | Pranger A. | Kosterink J.G.W., prof. dr. | Werf T.S. van der, prof. dr. | Uges D.R.A., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2018 | drug monitoring moxifloxacin exposure tuberculosis | |
A quest to optimize the clinical pharmacology of tuberculosis and human immunodeficiency virus drug treatment | Daskapan A., PhD | Werf T.S. van der, prof. dr. | Alffenaar J.W.C., prof. dr. | Stienstra Y., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2018 | Tuberculosis; Immunodeficiency virus drug treatment | |
Isoflurane induced eNOS signaling and cardioprotection: preconditioning mechanisms under normal and hyperglycemic conditions | Baotic I., PhD | Henning R.H., prof. dr. | Epema A.H., dr. | Rijksuniversiteit Groningen (RUG) | 2018 | Isoflurane; eNOS; cardioprotection | ||
Future drugs in atherosclerotic cardiovascular disease | Poelgeest E.P van | Burggraaf J., prof. dr. | Cohen A.F., prof. dr. | Universiteit Leiden (UL) | 2018 | Atherosclerosis Systemic inflammation Hypercholesterolemia PCSK9 inhibitor TLR4 sinaling Acute kidney injury Endothelial dysfunction Human endotoxemia model Ex vivo LPS challenge test Invivo LPS challenge test | ||
Fluorescence-guided cancer surgery:clinical translation of tumor targeted agents | Hoogstins C.E.S | Burggraaf J., prof. dr. | Cohen A.F., prof. dr. | Vahrmeijer A.L., Dr. | Universiteit Leiden (UL) | 2018 | Image-guided surgery Fluorescence Tumor targeted Oncological surgery | |
The use of a battery of evoked pain models in early phase drug development | Okkerse P. | Cohen A.F., prof. dr. | Groeneveld G.J., prof. dr. | Universiteit Leiden (UL) | 2018 | Pain Human pain models Analgesics Clinical pharmacology Pharmacodynamics Drug Development | ||
Sticky & Dirty Proteins- or on the poorly characterised, peculiar, pharmacokinetic and immunostimulatory aspects of biopharmaceuticals | Reijers J.A.A. | Burggraaf J., prof. dr. | Cohen A.F., prof. dr. | Universiteit Leiden (UL) | 2018 | Biopharmaeuticals Biologics Clinical Pharmacology Pharmacokinetics Adverse immunostimulation Immunotoxicity Drug impurity Drug contamination Monoclonal antibody | ||
First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children | Brussee J.M., PhD | Knibbe C.A.J., prof. dr. | Wildt S.N. de, prof. dr. | Krekels E.H.J., PhD | Universiteit Leiden (UL) | 2018 | Pharmacology; Pharmacokinetics; Paediatrics; Cytochrome P450; Drug metabolism; Midazolam; Population pharmacokinetics; Semi-PBPK modelling; CYP3A-mediated metabolism; First-pass metabolism; | |
How to scale clearance from adults to children for drugs undergoing hepatic metabolism? Insights from advanced PBPK modelling and simulation | Calvier E.A.M., PhD | Knibbe C.A.J., prof. dr. | Tibboel D., prof. dr. | Krekels E.H.J., PhD | Universiteit Leiden (UL) | 2018 | Paediatrics; Clearance; Allometric scaling; Hepatic metabolism; Physiologically based pharmacokinetics; Pharmacokinetics; Optimal design; Scaling clearance; | |
Pharmaceutical development, preclinical research and clinical application of the bone-targeting therapeutic radiopharmaceutical rhenium-188-HEDP | Lange R., PhD | Hendrikse N.H., prof. dr. | Heine R. ter, dr. | Bloemendal H.J., dr. | Vrije Universiteit Amsterdam (VU) | 2017 | Radiopharmaceutics; Pharmaceutical development; Rhenium; | |
Unintended effects of anti-hyperglycaemic drugs studied in population-based cohorts | Driessen J.H.M., PhD | Bergh J.P.W. van den, prof. dr. | Vries F. de, prof. dr. | Onzenoort H.A.W. van, PhD | Universiteit Maastricht (UM) | 2017 | Hyperglycaemic drugs; Population-based; | |
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation | Admiraal R., PhD | Knibbe C.A.J., prof. dr. | Boelens J.J., dr. | Bredius R.G.M., dr. | Universiteit Leiden (UL) | 2017 | ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy; | |
ColoPulse tablets in inflammatory bowel disease: formulation, potential application and evaluation | Maurer J.M., PhD | Kosterink J.G.W., prof. dr. | Frijlink H.W., prof. dr. | Woerdenbag H.J., dr. | Rijksuniversiteit Groningen (RUG) | 2017 | ColoPulse tablets; Inflammatory bowel disease; | |
Exploring optimal pharmacotherapy after bariatic surgery: where two worlds meet | Yska J.P., PhD | Roon E.N. van, prof. dr. | Wilffert B, prof. dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Optimal pharmacotherapy; Bariatric surgery; | ||
Variability in drug response: personalized diabetes care | Petrykiv S.I. | Lambers Heerspink H.J., prof. dr. | Zeeuw D. de, prof. dr. | Laverman G.D., dr. | Rijksuniversiteit Groningen (RUG) | 2017 | ||
Techniques to improve neurological outcome after cardiac surgery | Kok W.F., PhD | Henning R.H., prof. dr. | Absalom A.R., prof. dr. | Scheeren T.W.L., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Cardiac surgery; Clinical pharmacology; Neurological outcome; | |
Towards better fall prevention - examining the interplay between factors that influence gait in older patients | Groot M.H. de, PhD | Beijnen J.H., prof. dr. | Lamoth C.J.C., dr. | Universiteit Utrecht (UU) | 2017 | Falls; Gait analysis; Accelerometry; Frailty; Osteoporosis; Maturation; Medication use; Medication use; Geriatrics; Older patients; | ||
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasis | Kip A.E., PhD | Beijnen J.H., prof. dr. | Schellens J.H.M., prof. dr. | Dorlo T.P.C., dr. | Universiteit Utrecht (UU) | 2017 | Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin; | |
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safety | Noorsyahdy A.Y., MD PhD | Boer A. de, prof. dr. | Klungel O.H., prof. dr. | Deneer V.H.M., dr. | Universiteit Utrecht (UU) | 2017 | Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics; | |
Solid dispersions in oncology: a solution to solubility-limited oral drug absorption | Sawicki E., PhD | Beijnen J.H., prof. dr. | Schellens J.H.M., prof. dr. | Nuijen B., dr. | Universiteit Utrecht (UU) | 2017 | Solid dispersions; Pharmacokinetics; Spray drying; Freeze drying; Docetaxel; Paclitaxel; Elacridar; | |
Paving ways for personalizing drug therapy during pregnancy | Daud N.A.A., PhD | Wilffert B, prof. dr. | Kammen-Bergman J.E.H. van, dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Personalized medicine; Drug therapy; Pregnancy; | ||
Multimodality ImAging of Cardiovascular Dysfunction: Risk factors, diagnostics and treatment options | Thiel B.S. van, PhD | Kanaar R., prof. dr. | Danser A.H.J., prof. dr. | Essers J., dr. | Pluijm I. van der, dr. | Erasmus Universiteit Rotterdam (EUR) | 2017 | Cardiovascular disease; Imaging; Aging; Risk factors; Diagnostics; Treatment options |
Unravelling the link between diabetes, insulin treatment and breast cancer | Bronsveld H.K., PhD | Boer A. de, prof. dr. | Bruin M.L. de, prof. dr. | Schmidt M.K., dr. ir. | Universiteit Utrecht (UU) | 2017 | Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment; | |
Pharmacogenetics of sunitinib in metastatic renal cell carcinoma | Diekstra M.H.M., dr | Guchelaar H.J., prof. dr. | Swen J.J., PhD | Universiteit Leiden (UL) | 2017 | Genetics; Pharmacogenetics; Renal function; | ||
Renin-Synthesizing Cells and Beyond | Goes Martini A., PhD | Danser A.H.J., prof. dr. | Neves F.A.R., prof. dr. | Erasmus Universiteit Rotterdam (EUR) | 2017 | Renin-angiotensin system; Renal function; | ||
Multimodality ImAging of Cardiovascular Dysfunction: Risk Factors, Diagnostics and Treatment Options | Thiel B.S. van, PhD | Kanaar R., prof. dr. | Danser A.H.J., prof. dr. | Essers J., dr. | Pluijm I. van der, dr. | Erasmus Universiteit Rotterdam (EUR) | 2017 | Cardiovascular disease; Risk factors; Treatment options; |
DNA Damage-related Vascular Dysfunction: Pathways and Interventions | Bautista-Niño P.K., PhD | Danser A.H.J., prof. dr. | Franco Duran O.H., Prof.dr. | Roks A.J.M., dr. | Ghanbari M., dr. | Erasmus Universiteit Rotterdam (EUR) | 2017 | Cardiovascular disease; Vascular reactivity; DNA damage; |
Challenges in using cardiovascular medications in Sub-Saharan Africa | Berhe D.F., PhD | Haaijer-Ruskamp F.M., prof. dr. | Taxis K., prof. dr. | Mol P.G.M., dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Pharmacology; Medication use; Cardiovascular disease; | |
Evaluation of renal end points in nephrology trials. | Weldegiorgis M | Lambers Heerspink H.J., prof. dr. | Zeeuw D. de, prof. dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Pharmacology; Nephrology trials; renal endpoints | ||
Exploring strategies to individualize treatment with aminoglycosides and co-trimoxazole for MDR Tuberculosis | Dijkstra J.A., PhD | Werf T.S. van der, prof. dr. | Kosterink J.G.W., prof. dr. | Alffenaar J.W.C., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Personalized medicine; Tuberculosis; | |
Prediction and monitoring of chronic kidney disease | Boele-Schutte E., PhD | Gansevoort R.T., prof. dr. | Wolffenbuttel B.H.R., prof. dr. | Lambers Heerspink H.J., prof. dr. | Lutgers H.L., dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Pharmacology; Prediction; Kidney disease; |
Advanced vascular imaging : technical and clinical applications in type 2 diabetes | Boer S.A. de, PhD | Kamphuisen T.P.W., prof. dr. | Slart R.H.J.A., prof. dr. | Rijksuniversiteit Groningen (RUG) | 2017 | Pharmacology; advanced vascular imaging; Diabetes mellitus; | ||
Preclinical molecular imaging of target expression and target dynamics in cancer. | Pool M., PhD | Vries E.G.E. de, prof. dr. | Lub-de Hooge M.N., dr. | Terwisscha van Scheltinga A.G.T., PhD | Rijksuniversiteit Groningen (RUG) | 2017 | ||
Towards understanding interchangeability of generic drugs | Yu Y, dr | Neef C., prof. dr. | Burger D.M., prof. dr. | Universiteit Maastricht (UM) | 2017 |