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Displaying 1-50 of 270 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Clinical pharmacological aspects of mitochondrial function in muscle Diemen M.P.J. van, PhDCohen A.F., prof. dr.Nelissen R.G.H.H., prof. dr.Groeneveld G.J., prof. dr.Universiteit Leiden (UL)2021Clinical pharmacology; Huntington's disease; Mitochondrial function; Magnetic Resonance Spectroscopy; Sarcopenia; Phosphocreatine recovery rate; Knee; Total knee arthroplasty; Wearables; Peripheral blood mononuclear cells; Protoporphorin IX Triple State Lifetime techn;
Real-world treatment outcomes in metastatic lung cancer : from efficacy-effectiveness gap evaluation to informed clinical decision-makingWelle C.M. van derKlungel O.H., prof. dr.Groen H.J.M., prof. dr.Garde E.M.W. van de, dr.Schramel F.M.N.H., dr.Universiteit Utrecht (UU)2021Real-world data; Lung cancer; Treatment outcomes; Pharmacotherapy; Treatment patterns; Effectiveness; Survival; Pharmacoepidemiology; Web-based tool;
Clinical manifestations of sex hormonal influences in migraineCasteren D.S. van, PhDDanser A.H.J., prof. dr.Terwindt G.M., prof. dr.Maassen van den Brink A., dr.Universiteit Leiden (UL)2021Migraine; Clinical pharmacology; Treatment; Endocrinology; Pharmacology;
Salt, acid, and the renin-angiotensin system in chronic kidney diseaseBovée D.M., PhDHoorn E.J., prof. dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2021Renin-angiotensin system; Kidney; Pharmacology;
Investigations of skin inflammation with a novel dermatology toolbox for early phase clinical drug developmentKolk T. van der, drBurggraaf J., prof. dr.Rissmann R, prof.dr.Universiteit Leiden (UL)2021Skin inflammation Dermatology toolbox Early phase clinical drug development Trial at home Inflammation models Skin microbiome Atopic dermatitis
The role of glomerular filtration and active tubular secretion in predicting renal clearance of drugs in children using population pharmacokinetic and physiology-based pharmacokinetic modeling approaches: unspinning the yarnCristea S., PhDKnibbe C.A.J., prof. dr.Allegaert K., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2021Population PK; Optimise drug dosing; Paediatric renal clearance; PBPK; Paediatrics; Renal clearance; Population pharmacokinetics; Physiologically based pharmacokinetics; Maturation; Active tubular secretion; Renal transporters;
Osteoporotic fractures: relation to mortality, medication use, and rheumatoid arthritisAbtahi S., PhDVries F. de, prof. dr.Boonen A.E.R.C.H., prof. dr.Driessen J.H.M., PhDBurden A.M., dr.Universiteit Maastricht (UM)2021
Better prediction of drug response in diabetic kidney diseaseIdzerda N.M.A.Lambers Heerspink H.J., prof. dr.Zeeuw D. de, prof. dr.Pena M.J., PhDRijksuniversiteit Groningen (RUG)2020Diabetic kidney disease; Drug response;
Therapeutic drug monitoring in tuberculosis treatmentElsen S.H.J. van denAlffenaar J.W.C., prof. dr.Werf T.S. van der, prof. dr.Rijksuniversiteit Groningen (RUG)2020drug monitoring, tuberculosis treatment
Implementing dried blood spot sampling in transplant patient careTouw D.J., prof. dr.Touw D.J., prof. dr.Bakker S.J.L., prof. dr.Rijksuniversiteit Groningen (RUG)2020dried blood spot sampling, transplant patient care
Implementing dried spot sampling in transplant patient careVeenhof H.Touw D.J., prof. dr.Bakker S.J.L., prof. dr.Berger S.P., prof. dr.Rijksuniversiteit Groningen (RUG)2020dried blood spot; Transplantation;
Characterization and re-evaluation of experimental pain models in healthy subjectsSiebenga P.SCohen A.F., prof. dr.Universiteit Leiden (UL)2020Analgesics Human evoked pain models Neuropathic pain Nociceptive pain Pharmacodynamics Phase-1 clinical triala
Early phase clinical drug development for HPV-induced disorders: novel tools and treatmentsRijsbergen M.Burggraaf J., prof. dr.Rissmann R, prof.dr.Poelgeest M.I.E. van, dr.Universiteit Leiden (UL)2020HPV-induced diseases;
Rational use of antibioticsDijkmans A.C.Burggraaf J., prof. dr.Universiteit Leiden (UL)2020Antibiotics; Pharmacokinetics;Flucloxacillin;Penicillin; Pheneticillin;Rifampin;Colistin;Fosfomycin
Integrated assessment of neurocognitive, neurophysiological and pain processing in early clinical drug developmentAmerongen G. van, PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Groeneveld G.J., prof. dr.Universiteit Leiden (UL)2020Clinical pharmacology Pharmacodynamics Pain Human pain models Cannabinoid GABA THC Multiple sclerosis (MS)
New therapeutic targets in cardiovascular disease: focus on the renin-angiotensin system and lipid metabolismSun YDanser A.H.J., prof. dr.Lu X., PhDErasmus Universiteit Rotterdam (EUR)2020Renin-angiotensin system; lipid metabolism; Vascular reactivity; Pharmacology; Treatment options;
Towards New Therapies for Preeclampsia: Restoring Vascular DysfunctionHitzerd AEReiss IKM, prof.dr.Danser A.H.J., prof. dr.Simons SHP, dr.Erasmus Universiteit Rotterdam (EUR)2020Pre-eclampsia; Treatment options; Pregnancy; Pharmacology;
Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics: Tools of the tradeGoulooze S.C., PhDKnibbe C.A.J., prof. dr.Hankemeier T., prof. dr.Krekels E.H.J., PhDUniversiteit Leiden (UL)2020Population pharmacokinetics-pharmacodynamics; Repeated time-to-event modelling; Paediatric pharmacology; Pharmacometric methodology; Analgesia; Iatrogenic withdrawal; Postoperative pain; Item response theory (IRT); Analgesia and sedation; Real-world data; Paediatrics; Pharmacodynamics; Pharmacometrics;
Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity: Studies in adults, adolescents and childrenSmit C., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Brüggemann R.J.M., PhDUniversiteit Leiden (UL)2020Obesity; Morbid obesity; Pharmacokinetics; Obese children; Obese adolescents; Gentamicin; Tobramycin; Aminoglycosides; Vancomycin; Renal clearance; Population pharmacokinetics; Antibiotics; Individualized dosing; Adolescents;
Mounting an attack on the glioblastoma triad : proliferation, invasion and resistanceGooijer M.C. de, PhDBeijnen J.H., prof. dr.Tellingen O. van, dr.Universiteit Utrecht (UU)2019Glioblastoma; Blood-brain barrier; Therapy development; Pharmacology; Cell biology; Combination therapy; Mouse models;
Multi dose drug dispensing for older patients in primary careMertens B.J., PhDBouvy M.L., prof. dr.Marum R.J. van, prof. dr.Kwint H.F., dr.Universiteit Utrecht (UU)2019Elderly; Primary care; Multi-dose drug dispensing;
Biomarkers in real-life COPD managementOshagbemi O.A., PhDWouters E.F.M., prof. dr.Vries F. de, prof. dr.Franssen F.M.E., dr.Universiteit Maastricht (UM)2019
Insight in disease and drug interactions, with treatment optimisation of patients with cancerKnapen L.M., PhDTjan-Heijnen V.C.G., prof. dr.Vries F. de, prof. dr.Croes S., dr.Erp N.P. van, dr.Universiteit Maastricht (UM)2019
Bioanalysis and biotransformation of tyrosine kinase inhibitors in oncologyRood J.J.M., PhDBeijnen J.H., prof. dr.Sparidans R.W., dr.Universiteit Utrecht (UU)2019
Biomedical engineering for breathomics: towards clinical application in respitaroty diseases biomarker, instruments and Technology Readiness LevelsBrinkman P., PhDSterk P.J., prof. dr.Maitland-van der Zee A.H., prof. dr.Jongh F.H.C. de, dr.ir.Universiteit van Amsterdam (UvA)2019
Reversible suppression of hemostasis in hibernation and hypothermiaVrij E.L. deHenning R.H., prof. dr.Bouma H.R., PhDRijksuniversiteit Groningen (RUG)2019Hypothermia; Hibernation;
Use of real-world evidence in pharmaeconomic analysisHuang Y.Haaijer-Ruskamp F.M., prof. dr.Postma M.J., prof. dr.Rijksuniversiteit Groningen (RUG)2019Pharmacogenomics;
Clinical pharmcology of ertapenem in the treatment of multidrug-resistant tuberculosisRijn S.P. vanAlffenaar J.W.C., prof. dr.Werf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Rijksuniversiteit Groningen (RUG)2019Tuberculosis; multidrug-resistant
Optimizing levofloxacin dose in the treatment of multidrug-resistant tuberculosisGhimire S.Alffenaar J.W.C., prof. dr.Touw D.J., prof. dr.Werf T.S. van der, prof. dr.Rijksuniversiteit Groningen (RUG)2019
Clinical pharmacology and therapeutic drug monitoring of voriconazoleVeringa A., PhDAlffenaar J.W.C., prof. dr.Kosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Rijksuniversiteit Groningen (RUG)2019drug monitoring; voriconazole
The Clinical Pharmacology of performance enhancement and doping detection in sportsHeuberger J., dr.Cohen A.F., prof. dr.Groeneveld G.J., prof. dr.Rotmans J.I., dr.Universiteit Leiden (UL)2019Performance enhancement and doping detection in sports
Measuring pharmacodynamics in early clinical drug studies in multiple sclerosisKanhai K.M.SCohen A.F., prof. dr.Groeneveld G.J., prof. dr.Universiteit Leiden (UL)2019Multiple sclerosis Drug development Biomarkers Remyelination
Fluorescence-enhanced surgical navigation : towards tailored tumor detectionBoogerd L.S.F., PhDVelde C.J.H. Van de, Prof.dr.Burggraaf J., prof. dr.Vahrmeijer A.L., Dr.Universiteit Leiden (UL)2019Fluorescence guided surgery tailored tumor detection Intraoperative tumor imaging ICG CEA targeted tumor detection
The quantification of growth hormone secretion : application of model-informed drug development in acromegalyEsdonk M.J vanGraaf P.H., Prof.dr.Burggraaf J., prof. dr.Stevens J., Dr.Universiteit Leiden (UL)2019Endocrinology Pulsatile profiles Population modelling Pharmacokinetic Pharmacodynamic modelling Clinical trial simulation
Vascular Effects of Current and Novel Antimigraine DrugsRubio Beltrán AEDanser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2019Migraine; Vascular reactivity; Drug efficacy; Pharmacology;
Peripheral Projections of the Trigeminovascular System as Antimigraine TargetLabastida Ramírez ADanser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2019Migraine; Vascular reactivity; Pharmacology;
The aging cardiovascular system: genetic and epigenetic determinants of vascular outcomes and cardiometabolic riskPortilla Fernández EDanser A.H.J., prof. dr.Ikram MA, prof.dr.Roks A.J.M., dr.Dehghan A, dr.Erasmus Universiteit Rotterdam (EUR)2019Cardiac aging; Cardiovascular disease; Genetics; Epidemiology; Epigenetics; Vascular reactivity; Pharmacology;
Antifungal pharmacokinetics in the era of the obesity pandemicWasmann R.E., PhDBurger D.M., prof. dr.Knibbe C.A.J., prof. dr.Brüggemann R.J.M., PhDRadboud Universiteit (RU)2019Antifungal drugs; Clinical pharmacology; Morbid obesity; Micafungin; Anidulafungin; Posaconazole; Liposomal amphotericinB;
Comorbidities, complications and treatment of childhood obesityLentferink Y.E., PhDKnibbe C.A.J., prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2019Children; Obesity; Asthma; ADHD; Insulin resistance; Metformin; Cardiovascular diseases; Obese children; Arterial stiffness; Skin autofluorescence;
Rational prescribing in Europe: are future doctors well prepared?Brinkman D.J., PhDAgtmael M.A. van, prof. dr.Richir M.C., MD PhDTichelaar J., dr.Vrije Universiteit Amsterdam (VU)2018Clinical pharmacology; Pharmacotherapy; Prescribing;
Osteoarthritis : association with diabetes mellitus, and treatment-related outcomesNielen J.T.H., PhDBoonen A.E.R.C.H., prof. dr.Dagnelie P.C., prof. dr.Vries F. de, prof. dr.Bemt B.J.F. van den, dr.Universiteit Maastricht (UM)2018Osteoarthritis; Diabetes mellitus; Hip; Knee; Treatment outcomes;
Learning in a student-run clinic: a new concept to improve medical education in pharmacotherapySchutte T., PhDAgtmael M.A. van, prof. dr.Richir M.C., MD PhDTichelaar J., dr.Vrije Universiteit Amsterdam (VU)2018Pharmacotherapy education; Student-run clinic; Medical education; Workplace learning; Undergraduate education;
Angiogenic imbalance in preeclampsia: pathogenic, diagnostic and prognostic implicationsSaleh L., PhDDanser A.H.J., prof. dr.Steegers E.A.P., prof. dr.Meiracker A.H. van den, dr.Visser W, Dr.Erasmus Universiteit Rotterdam (EUR)2018Pre-eclampsia; Pregnant women; Pregnancy; Renin-angiotensin system; Treatment options;
Endothelial dysfunction in cardiovascular diseaseHeuvel M. van den, PhDDuncker D.J.G.M., Prof.dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2018Cardiovascular disease; Vascular reactivity; Cholesterol;
Medication optimisation : methodological aspects and new strategiesMestres Gonzalvo C., PhDVerhey F.R., prof.dr.Kuy P.H.M. van der, dr.Janknegt R., PharmD PhDUniversiteit Maastricht (UM)2018Elderly; Geriatrics; Hospital pharmacists; Medication use; Model-based; Model validation; Older patients; Optimal pharmacotherapy; Pharmaceutical care; Pharmacotherapy; Pharmacovigilance;
Quality of presribing in chronic kidney disease and type 2 diabetes. Smits K.P.J.Denig P., prof. dr.Muro E.P., PhDSidorenkov G., PhDRijksuniversiteit Groningen (RUG)2018Pharmacology; Prescribing; Chronic kidney disease;
Cardiovascular molecular imagingHaas H.J. de, PhDDierckx R.A.J.O., prof. dr.Slart R.H.J.A., prof. dr.Boersma H.H., dr.Rijksuniversiteit Groningen (RUG)2018Pharmacology; Cardiovascular molecular imaging
Albuminuria: more than a renal risk marker? Belt S.M. van den, PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Rijksuniversiteit Groningen (RUG)2018Albuminuria; Risk markers;
Preclinical molecular imgaging to study the biodistribution of antibody derivatives in oncology. Warnders J.F., PhDKosterink J.G.W., prof. dr.Vries E.G.E. de, prof. dr.Lub-de Hooge M.N., dr.Rijksuniversiteit Groningen (RUG)2018preclinical molecular imaging; oncology
Monitoring patients using psychotropic drugsNederlof M., PhDEgberts A.C.G., prof. dr.Heerdink E.R., dr.Universiteit Utrecht (UU)2018Therapeutic drug monitoring; Biomarkers; Benefit-risk assessment; Psychotropic drugs; Psychiatry; Antidepressants; Antipsychotics
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