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Displaying 1-50 of 155 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Methods for improving the safety of fluoropyrimidine anticancer drugsJacobs B.A.W., PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2016Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Thymidylate synthase; Safety; Phenotyping; Circadian rhythm;
(Pro)renin revisited: new insights from studies in mast cellsKrop M., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2009Cardiovascular disease; Pharmacology; Prorenin;
Acute and chronic pain after cardiac surgeryGulik L. van, PhDKnibbe C.A.J., prof. dr.Tibboel D., prof. dr.Bruins P., dr.Universiteit Leiden (UL)2014Acute pain; Intensive Care Unit; Chronic pain; Cardiac surgery; Pain management;
Adherence to antiretroviral combination therapy in children : what a difference half a day makes...Piana C., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2013Pediatrics; Antiretroviral combination therapy; Compliance; Antiretroviral drugs; Pediatric populations; Drug combinations; Model-based; Covariate analysis; Predictive pharmacokinetic models; Clinical trial simulations; Adherence; Forgiveness of non-adherence;
Adverse drug reactions of angiotensin-converting enzyme inhibitors : towards precicion medicineMahmoud Pour S.H., PhDBoer A. de, prof. dr.Asselbergs F.W., MD PhD FESMaitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Adverse drug reaction; Pharmacoepidemiology; Pharmacovigilance; ACE Inhibitors
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factorsBatenburg W.W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safetyNoorsyahdy A.Y., MD PhDBoer A. de, prof. dr.Klungel O.H., prof. dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2017Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics;
Aortic pathology and the role of the renin-angiotensin systemMolzer E., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Cardiovascular disease; Renin-angiotensin system;
Assessment of ischaemia and reperfusion injuryWouters C.W., PhDRongen G.A., prof. dr.Oyen W.J.G., prof. dr.Radboud Universiteit (RU)2013Ischemia/reperfusion injury; adenosine; atorvastatin; forearm;
Biomarkers as assessment of drug efficacy in cardiovascular diseaseSmink P.A., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Bakker S.J.L., prof. dr.Rijksuniversiteit Groningen (RUG)2013cardiovascular disease biomarkers drug efficacy
Building a clinical pharmacology framework for the safe and effective use of antifungal agentsLempers VJCBurger D.M., prof. dr.Brüggemann R.J.M., PhDAarnoutse R.E., dr.Radboud Universiteit (RU)2016Antifungal drugs; Clinical pharmacology;
Cardiac aldosterone: origin and effectsChai W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Cardiovascular, renal and thyroid toxicity during angiogenesis inhibition: a translational approachKappers M.H.W., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Cancer; Pharmacology; Antihypertensive drugs;
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthmaLeusink M., PhDBoer A. de, prof. dr.Bakker P.I.W. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Onland-Moret N.C., dr.Universiteit Utrecht (UU)2015Pharmacogenomics; Cardiovascular disease; Asthma; Genomics; Genetics; Pharmacology; Statins; Inhaled corticosteroids; Cholesterol;
Challenges in the clinical development of orphan drugsKreeftmeijer-Vegter A.R., PhDBoer A. de, prof. dr.Vries P.J. de, dr.Universiteit Utrecht (UU)2015Orphan drugs; Clinical development; Paediatric formulation; Pharmacokinetics; Efficacy; Safety; Regulatory;
Characterization of vascular 5-hydroxytryptamine, adrenergic and CGRP receptors in relation to migraineMehrotra S., dr.Saxena P.R., prof. dr.Danser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2006Cardiovascular disease; Pharmacology;
Clinical pharmacological studies in tuberculosis patientsSemvua H.H., PhDBurger D.M., prof. dr.Aarnoutse R.E., dr.Boeree M.J., dr.Radboud Universiteit (RU)2014Clinical pharmacology; Pharmacokinetics; Tuberculosis
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasisKip A.E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Dorlo T.P.C., dr.Universiteit Utrecht (UU)2017Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin;
Clinical pharmacology and therapeutic drug monitoring of first-line anti-tuberculosis drugsSturkenboom M.G.G., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis; Therapeutic drug monitoring;
Clinical pharmacology of genotype-directed anticancer therapy - Towards rational combination strategiesGeel R.M.J.M. van, PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Huitema A.D.R., prof. dr.Cats A., dr.Universiteit Utrecht (UU)2016Cancer; Genetics; BRAF; Colorectal cancer; Combination therapy; p53-deficient ovarian cancer; AZD1775; Treatment individualization;
Clinical pharmacology of nevirapine in HIV-infected patients in TanzaniaMuro E.P., PhDBurger D.M., prof. dr.Dolmans W.M.V., prof. dr.Radboud Universiteit (RU)2014Clinical pharmacology; HIV; Pharmacokinetics; therapy drug monitoring
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studiesNijenhuis C.M., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Rosing H., dr.Universiteit Utrecht (UU)2016
Clinical risk management of drug-related hospital admissions: strategies for their identification, reduction and monitoringWarlé-van Herwaarden M., PhDSmet P.A.G.M. de, prof. dr.Sturkenboom M.C.J.M., prof. dr.Kramers C., dr.Herings R.M.C., dr.Radboud Universiteit (RU)2015Guideline adherence; medication safety; laboratory monitoring
Cognition in Huntington's disease : the influence of motor behaviour and time Hart E.P. 't, PhDRoos R.A.C., prof. dr.Universiteit Leiden (UL)2013Huntington's disease; Cognition; Movement disorder; Executive functioning; Memory; P300; Motor behaviour
ColoPulse tablets in inflammatory bowel disease: formulation, potential application and evaluationMaurer J.M., PhDKosterink J.G.W., prof. dr.Frijlink H.W., prof. dr.Woerdenbag H.J., dr.Rijksuniversiteit Groningen (RUG)2017ColoPulse tablets; Inflammatory bowel disease;
Communicating risk effectivelyPiening S., PhDHaaijer-Ruskamp F.M., prof. dr.Graeff P.A. de, prof. dr.Mol P.G.M., dr.Straus S.M.J.M., dr.Rijksuniversiteit Groningen (RUG)2013risk effectivity communicating risk drugs
COMPARE: Care in Oncolytic Medication surveillance:Pharmacovigilance, Acceptability, Risks and EventsOijen B.P.C. van, dr.Schouten H.C., prof. dr.Kuy P.H.M. van der, dr.Janknegt R., PharmD PhDUniversiteit Maastricht (UM)2015Chemotherapy; Clinical pharmacology; Pharmaceutical care;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgeryBrill M.J.E., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Diagnosis and treatment of obese children with insulin resistanceAa M.P. van der, PhDKnibbe C.A.J., prof. dr.Boer A. de, prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2016Obesity; Children; Insulin resistance; Metformin;
Don't be afraid! Population PK-PD modeling as the basis for individualized dosing in children and critically illPeeters M.Y.M., dr.Danhof M., prof. dr.Tibboel D., prof. dr.Knibbe C.A.J., prof. dr.Universiteit Leiden (UL)2007Pharmacokinetics; Pharmacodynamics; Children; Sedation; Critically ill; Intensive care; NONMEM; Propofol; Midazolam;
Driving-impairing medicines and traffic safety: patients' perspectivesMonteiro S.P., PhDGier J.J. de, prof. dr.Dijk C.E.M.J. van, dr. ir.Rijksuniversiteit Groningen (RUG)2014
Drug effects on the risk and prognosis of community-acquired pneumoniaGarde E.M.W. van de, dr.Leufkens H.G.M., prof. dr.Bosch J.M.M. van den, prof. dr.Souverein P.C., dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2007Pneumonia; Adults; Clinical outcomes; Prevention;
Drug-induced psychomimetic symptoms as a model for psychosisKleinloog-Fernández González H.D., PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2014Clinical Pharmacology Psychotic Disorders Clinical Trial Drug evaluation Biological Models
Drug-related problems: risk factors and the role of clinical pharmacistsZaal R.J., PhDVulto A.G., prof. dr.Haaijer-Ruskamp F.M., prof. dr.Bemt P.M.L.A. van den, dr.Erasmus Universiteit Rotterdam (EUR)2016Drug-related problems; Risk factors;
End-organ damage in diabetes: exploring innovative targets and therapiesHamidi M., PhDHenning R.H., prof. dr.Buikema J.H., dr.Deelman L.E., dr.Rijksuniversiteit Groningen (RUG)2015Diabetes mellitus;
Experimental focal cerebral ischemia: optimalisation of models and therapeutic interventionsShanbhag N.C., PhDHenning R.H., prof. dr.Schilling L., prof. dr.Rijksuniversiteit Groningen (RUG)2016Cerebral ischemia;
Exploring optimal pharmacotherapy after bariatic surgery: where two worlds meetYska J.P., PhDRoon E.N. van, prof. dr.Wilffert B, prof. dr.Rijksuniversiteit Groningen (RUG)2017Optimal pharmacotherapy; Bariatric surgery;
Exploring the role of glucagon in glucose homeostasisDongen M.G.J. van, PhDCohen A.F., prof. dr.Romijn J.A., prof drBurggraaf J., prof. dr.Universiteit Leiden (UL)2015Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
Exposure to antiretroviral agents in hiv-infected pregnant women: not too much-not too littleColbers EPH, dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2015HIV; antiretroviral agents; clinical pharmacology; drug drug interactions
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in childrenBellanti F., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2015Benefit-risk assessment; Pediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Harmonising relative effectiveness assessments of medicines in EuropeKleijnen S., PhDBoer A. de, prof. dr.Leufkens H.G.M., prof. dr.Goettsch W.G., dr.Universiteit Utrecht (UU)2016Medicines; Relative effectiveness; Reimbursement; Harmonisation; Europe; Methods; Health technology assessment (HTA);
HIV treatment: a clinical pharmacology perspectiveLuin M. van, dr.Hekster Y.A., prof. dr.Burger D.M., prof. dr.Richter C., dr.Radboud Universiteit (RU)2010Clinical pharmacology; Pharmacokinetics; HIV; Therapeutic drug monitoring; drug-drug interactions; antiretroviral drugs
Human in vivo studies on the non-glycaemic effects of thiazolidinedione derivativesRennings A.J.M., dr.Smits P., prof. dr.Tack C.J.J., prof. dr.Radboud Universiteit (RU)2014
Hypertension and renal toxicity during angiogenesis inhibition: Salt dependency and treatment optionsLankhorst S.Danser A.H.J., prof. dr.Meiracker A.H. van den, dr.Kappers M.H.W., PhDErasmus Universiteit Rotterdam (EUR)2016Hypertension; Renal function; Treatment options
Immunological aspects of hibernation as leads in the prevention of acute organ injury.Bouma H.R., PhDHenning R.H., prof. dr.Kroese F.G.M., prof. dr.Strijkstra A.M., dr.Rijksuniversiteit Groningen (RUG)2013hibernation acute organ injury immunological
Implications of the cardiomyocyte stress response on protein homeostasis in atrial fibrillationWiersma M., PhDHenning R.H., prof. dr.Brundel B.J.J.M., dr.Rijksuniversiteit Groningen (RUG)2016Atrial fibrillation;
Improving the physical health of people with severe mental illness : the need for tailor made care and uniform evaluation of interventionsHasselt F.M. van, PhDLoonen A.J.M., prof. dr.Oud M.J.T., dr.Krabbe P.F.M., dr.Rijksuniversiteit Groningen (RUG)2013
Individualization of drug exposure in pediatric hematopoietic stem cell transplantationBartelink I.H., PhDEgberts A.C.G., prof. dr.Danhof M., prof. dr.Boelens J.J., dr.Knibbe C.A.J., prof. dr.Universiteit Utrecht (UU)2012Pediatrics; Busulfan; Hematopoietic stem cell transplantation;
Individualized dosing of calcineurin inhibitors in renal transplantationPress R.R., PhDGuchelaar H.J., prof. dr.Fijter J.W. de, prof. dr.Ploeger B.A., dr.Universiteit Leiden (UL)2011Kidney; Transplantation; Calcineurin inhibitors;
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantationAdmiraal R., PhDKnibbe C.A.J., prof. dr.Boelens J.J., dr.Bredius R.G.M., dr.Universiteit Leiden (UL)2017ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy;
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