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Displaying 1-50 of 199 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Methods for improving the safety of fluoropyrimidine anticancer drugsJacobs B.A.W., PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2016Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Thymidylate synthase; Safety; Phenotyping; Circadian rhythm;
(Pro)renin revisited: new insights from studies in mast cellsKrop M., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2009Cardiovascular disease; Pharmacology; Prorenin;
Acute and chronic pain after cardiac surgeryGulik L. van, PhDKnibbe C.A.J., prof. dr.Tibboel D., prof. dr.Bruins P., dr.Universiteit Leiden (UL)2014Acute pain; Intensive Care Unit; Chronic pain; Cardiac surgery; Pain management;
Adequate antimicrobial treatment in elderly patientsHaeseker M.B., drVerbon A., prof.dr.Stolk L.M.L., drUniversiteit Maastricht (UM)2015Antibiotics; Elderly;
ADHD medication use and long-term consequencesBan E.F. van den, PhDEgberts A.C.G., prof. dr.Swaab-Barneveld J.T., prof. dr.Heerdink E.R., dr.Universiteit Utrecht (UU)2014ADHD medication use; Long-term consequences;
Adherence to antiretroviral combination therapy in children : what a difference half a day makes...Piana C., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2013Pediatrics; Antiretroviral combination therapy; Compliance; Antiretroviral drugs; Pediatric populations; Drug combinations; Model-based; Covariate analysis; Predictive pharmacokinetic models; Clinical trial simulations; Adherence; Forgiveness of non-adherence;
Advanced vascular imaging; Technical and clinical applications in type 2 diabetes. Boer S.A. deKammen-Bergman J.E.H. van, dr.0
Advanced vascular imaging; Technical and clinical applications in type 2 diabetes. Boer S.A. deKamphuisen T.P.W., prof. dr.Slart R.H.J.A., prof. dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; advanced vascular imaging; Diabetes mellitus;
Adverse drug reactions in individual patient care : documentation and prevention of represcriptionLinden C.M.J. van der, PhDKorsten H.H.M., prof. dr.Egberts A.C.G., prof. dr.Jansen P.A.F., dr.Grouls R.J.E., dr.Technische Universiteit Eindhoven (TUE)2013Adverse drug reactions; Patient care; Prevention; Represcription;
Adverse drug reactions of angiotensin-converting enzyme inhibitors : towards precicion medicineMahmoud Pour S.H., PhDBoer A. de, prof. dr.Asselbergs F.W., prof. dr. MD FESMaitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Adverse drug reaction; Pharmacoepidemiology; Pharmacovigilance; ACE Inhibitors
Albuminuria: more than a renal risk marker? Belt S.M. van denZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Rijksuniversiteit Groningen (RUG)2018Albuminuria; Risk markers;
Angiogenic Imbalance in Preeclampsia: Pathogenic, Diagnostic and Prognostic ImplicationsSaleh LDanser A.H.J., prof. dr.Steegers E.A.P., prof. dr.Meiracker A.H. van den, dr.Visser W, Dr.Erasmus Universiteit Rotterdam (EUR)2018Pre-eclampsia; Pregnant women; Pregnancy; Renin-angiotensin system; Treatment options;
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factorsBatenburg W.W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safetyNoorsyahdy A.Y., MD PhDBoer A. de, prof. dr.Klungel O.H., prof. dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2017Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics;
Antipsychotics, delirium and glucose in older patientsKeulen K. van, PhDEgberts A.C.G., prof. dr.Knol W., PhDHeerdink E.R., dr.Universiteit Utrecht (UU)2018Antipsychotics; Older patients; Delirium; Hypoglycemia; Hyperglycemia; Incapacitated patients; Glucose variability;
Aortic pathology and the role of the renin-angiotensin systemMolzer E., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Cardiovascular disease; Renin-angiotensin system;
Appropriate prescribing for older peopleDrenth-van Maanen A.C., PhDEgberts A.C.G., prof. dr.Jansen P.A.F., dr.Marum R.J. van, prof. dr.Universiteit Utrecht (UU)2013Prescribing; Elderly; Polypharmacy; Transitional pharmaceutical care;
Assessing the impact of gout:validating and understanding outcomesSpaetgens B.P.A., drBoonen A.E.R.C.H., prof. dr.Vries F. de, dr.Universiteit Maastricht (UM)2017
Assessment of ischaemia and reperfusion injuryWouters C.W., PhDRongen G.A., prof. dr.Oyen W.J.G., prof. dr.Radboud Universiteit (RU)2013Ischemia/reperfusion injury; adenosine; atorvastatin; forearm;
Biomarkers as assessment of drug efficacy in cardiovascular diseaseSmink P.A., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Bakker S.J.L., prof. dr.Rijksuniversiteit Groningen (RUG)2013cardiovascular disease biomarkers drug efficacy
Building a clinical pharmacology framework for the safe and effective use of antifungal agentsLempers VJCBurger D.M., prof. dr.Brüggemann R.J.M., PhDAarnoutse R.E., dr.Radboud Universiteit (RU)2016Antifungal drugs; Clinical pharmacology;
Cardiac aldosterone: origin and effectsChai W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Cardiovascular Molecular Imaging. Haas H.J. deDierckx R.A.J.O., prof. dr.Slart R.H.J.A., prof. dr.Boersma H.H., dr.Rijksuniversiteit Groningen (RUG)2018Pharmacology; Cardiovascular molecular imaging
Cardiovascular, renal and thyroid toxicity during angiogenesis inhibition: a translational approachKappers M.H.W., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Cancer; Pharmacology; Antihypertensive drugs;
Carotid Artery Contrast Enhanced UltrasoundKate GL tenSijbrands E.J.G., prof. dr.Danser A.H.J., prof. dr.Schinkel A.F.L., Dr.Erasmus Universiteit Rotterdam (EUR)2014Cardiovascular disease; Vascular reactivity;
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthmaLeusink M., PhDBoer A. de, prof. dr.Bakker P.I.W. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Onland-Moret N.C., dr.Universiteit Utrecht (UU)2015Pharmacogenomics; Cardiovascular disease; Asthma; Genomics; Genetics; Pharmacology; Statins; Inhaled corticosteroids; Cholesterol;
Challenges in the clinical development of orphan drugsKreeftmeijer-Vegter A.R., PhDBoer A. de, prof. dr.Vries P.J. de, dr.Universiteit Utrecht (UU)2015Orphan drugs; Clinical development; Paediatric formulation; Pharmacokinetics; Efficacy; Safety; Regulatory;
Challenges in using cardiovascular medications in Sub-Saharan AfricaBerhe D.F., PhDHaaijer-Ruskamp F.M., prof. dr.Taxis K., prof. dr.Mol P.G.M., dr.Rijksuniversiteit Groningen (RUG)2017Pharmacology; Medication use; Cardiovascular disease;
Characterization of vascular 5-hydroxytryptamine, adrenergic and CGRP receptors in relation to migraineMehrotra S., dr.Saxena P.R., prof. dr.Danser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2006Cardiovascular disease; Pharmacology;
Child friendly medicines : availability, pharmaceutical design, usability and patient outcomesRiet-Nales D.A. van, PhDSchobben A.F.A.M., prof. dr.Egberts A.C.G., prof. dr.Rademaker C.M.A., dr.Universiteit Utrecht (UU)2014Pediatrics; Drug compounding; Consumer satisfaction; Formulation; Mini tablet; Splitter; Usability; EMA;
Clinical pharmacological studies in tuberculosis patientsSemvua H.H., PhDBurger D.M., prof. dr.Aarnoutse R.E., dr.Boeree M.J., dr.Radboud Universiteit (RU)2014Clinical pharmacology; Pharmacokinetics; Tuberculosis
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasisKip A.E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Dorlo T.P.C., dr.Universiteit Utrecht (UU)2017Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin;
Clinical pharmacology and therapeutic drug monitoring of first-line anti-tuberculosis drugsSturkenboom M.G.G., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis; Therapeutic drug monitoring;
Clinical pharmacology of genotype-directed anticancer therapy - Towards rational combination strategiesGeel R.M.J.M. van, PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Huitema A.D.R., prof. dr.Cats A., dr.Universiteit Utrecht (UU)2016Cancer; Genetics; BRAF; Colorectal cancer; Combination therapy; p53-deficient ovarian cancer; AZD1775; Treatment individualization;
Clinical pharmacology of nevirapine in HIV-infected patients in TanzaniaMuro E.P., PhDBurger D.M., prof. dr.Dolmans W.M.V., prof. dr.Radboud Universiteit (RU)2014Clinical pharmacology; HIV; Pharmacokinetics; therapy drug monitoring
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studiesNijenhuis C.M., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Rosing H., dr.Universiteit Utrecht (UU)2016
Clinical risk management of drug-related hospital admissions: strategies for their identification, reduction and monitoringWarlé-van Herwaarden M., PhDSmet P.A.G.M. de, prof. dr.Sturkenboom M.C.J.M., prof. dr.Kramers C., dr.Herings R.M.C., dr.Radboud Universiteit (RU)2015Guideline adherence; medication safety; laboratory monitoring
Cognition in Huntington's disease : the influence of motor behaviour and time Hart E.P. 't, PhDRoos R.A.C., prof. dr.Universiteit Leiden (UL)2013Huntington's disease; Cognition; Movement disorder; Executive functioning; Memory; P300; Motor behaviour
ColoPulse tablets in inflammatory bowel disease: formulation, potential application and evaluationMaurer J.M., PhDKosterink J.G.W., prof. dr.Frijlink H.W., prof. dr.Woerdenbag H.J., dr.Rijksuniversiteit Groningen (RUG)2017ColoPulse tablets; Inflammatory bowel disease;
Communicating risk effectivelyPiening S., PhDHaaijer-Ruskamp F.M., prof. dr.Graeff P.A. de, prof. dr.Mol P.G.M., dr.Straus S.M.J.M., dr.Rijksuniversiteit Groningen (RUG)2013risk effectivity communicating risk drugs
COMPARE: Care in Oncolytic Medication surveillance:Pharmacovigilance, Acceptability, Risks and EventsOijen B.P.C. van, dr.Schouten H.C., prof. dr.Kuy P.H.M. van der, dr.Janknegt R., PharmD PhDUniversiteit Maastricht (UM)2015Chemotherapy; Clinical pharmacology; Pharmaceutical care;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgeryBrill M.J.E., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Continuity of pharmaceutical care for psychiatric patientsAbdullah-Koolmees H., PhDEgberts A.C.G., prof. dr.Heerdink E.R., dr.Gardarsdottir H., dr.Universiteit Utrecht (UU)2015Pharmaceutical care; Medication; Hospitalization; Somatic; Discharge; Discontinuation; Rehospitalization; Rehospitalization prediction;
Determinants of treatment outcomes in epilepsyWassenaar M., PhDEgberts A.C.G., prof. dr.Leijten F.S.S., dr.Uijl S.G., dr.Universiteit Utrecht (UU)2014Epilepsy; Treatment; Treatment outcomes; Quality of life; Patient-perspectives; Clinical determinants; Seizures; Pharmacology; Daily practice; Community-based;
Diagnosis and treatment of obese children with insulin resistanceAa M.P. van der, PhDKnibbe C.A.J., prof. dr.Boer A. de, prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2016Obesity; Children; Insulin resistance; Metformin;
DNA Damage-related Vascular Dysfunction: Pathways and InterventionsBautista-Niño P.K., PhDDanser A.H.J., prof. dr.Franco Duran O.H., Prof.dr.Roks A.J.M., dr.Ghanbari M., Dr.Erasmus Universiteit Rotterdam (EUR)2017Cardiovascular disease; Vascular reactivity; DNA damage;
Don't be afraid! Population PK-PD modeling as the basis for individualized dosing in children and critically illPeeters M.Y.M., dr.Danhof M., prof. dr.Tibboel D., prof. dr.Knibbe C.A.J., prof. dr.Universiteit Leiden (UL)2007Pharmacokinetics; Pharmacodynamics; Children; Sedation; Critically ill; Intensive care; NONMEM; Propofol; Midazolam;
Driving-impairing medicines and traffic safety: patients' perspectivesMonteiro S.P., PhDGier J.J. de, prof. dr.Dijk C.E.M.J. van, dr. ir.Rijksuniversiteit Groningen (RUG)2014
Drug effects on the risk and prognosis of community-acquired pneumoniaGarde E.M.W. van de, dr.Leufkens H.G.M., prof. dr.Bosch J.M.M. van den, prof. dr.Souverein P.C., dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2007Pneumonia; Adults; Clinical outcomes; Prevention;
Drug-induced psychomimetic symptoms as a model for psychosisKleinloog-Fernández González H.D., PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2014Clinical Pharmacology Psychotic Disorders Clinical Trial Drug evaluation Biological Models
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