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Displaying 1-50 of 145 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Diagnosis and treatment of obese children with insulin resistanceAa M.P. van der, PhDKnibbe C.A.J., prof. dr.Boer A. de, prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2016Obesity; Children; Insulin resistance; Metformin;
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantationAdmiraal R., PhDKnibbe C.A.J., prof. dr.Boelens J.J., dr.Bredius R.G.M., dr.Universiteit Leiden (UL)2017ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy;
Pain still hurts : pain assessment and pain management in intensive care patientsAhlers S.J.G.M., PhDTibboel D., prof. dr.Knibbe C.A.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2012Morphine; Remifentanil; Pain; Immune reconstitution; Intensive care; Critically ill; Analgesia; Anesthesiology; Pain assessment; Pain management;
Risk factors and treatment of paediatric chronic diseases - Type 1 diabetes, asthma and allergyAhmadizar F., PhDBoer A. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Children; Diabetes mellitus; Allergy
Revisiting co-trimoxazole for the treatment of tuberculosisAlsaad N.S.I., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis;
Preclinical targeting of the tumor microenvironment. Possibilities and consequencesArjaans M., PhDVries E.G.E. de, prof. dr.Schröder C.P., dr.Timmer-Bosscha H., dr.Rijksuniversiteit Groningen (RUG)2015
Regulatory benefit-risk assessment : different perspectivesArnardottir A.H., dr.Haaijer-Ruskamp F.M., prof. dr.Graeff P.A. de, prof. dr.Mol P.G.M., dr.Straus S.M.J.M., dr.Rijksuniversiteit Groningen (RUG)2013drug registration benefit risk
Individualization of drug exposure in pediatric hematopoietic stem cell transplantationBartelink I.H., PhDEgberts A.C.G., prof. dr.Danhof M., prof. dr.Boelens J.J., dr.Knibbe C.A.J., prof. dr.Universiteit Utrecht (UU)2012Pediatrics; Busulfan; Hematopoietic stem cell transplantation;
Making things easier: how to improve antiviral drug treatment for childrenBastiaans D.E.T., dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2016Clinical pharmacology; Antiviral drug treatment;
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factorsBatenburg W.W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Neuropharmacology of novel dopamine modulators Beek E.T te, PhDGerven J.M.A. van, prof. dr.Cohen A.F., prof. dr.Universiteit Leiden (UL)2014Dopamine Antagonist Drug development Pharmacokinetics Pharmacodynamics Schizophrenia Drug addiction Tachykinins
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in childrenBellanti F., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2015Benefit-risk assessment; Pediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Optimizing treatment with psychotropic agents through precision drug therapy: It is not about the meanBerm E.J.J., PhDWilffert B, prof. dr.Hak E., prof. dr.Maring J.G., dr.Rijksuniversiteit Groningen (RUG)2016Drug therapy; Psychotropic agents; Treatment individualization; Precision medicine;
Linezolid in multidrug-resistant tuberculosisBolhuis M.S., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015Tuberculosis; Linezolid;
Red wine polyphenols and vascular functionBotden I.P.G., PhDDanser A.H.J., prof. dr.Sijbrands E.J.G., prof. dr.Langendonk J.G., dr.Erasmus Universiteit Rotterdam (EUR)2012Antihypertensive drugs; Cardiovascular disease; Pharmacology;
Immunological aspects of hibernation as leads in the prevention of acute organ injury.Bouma H.R., PhDHenning R.H., prof. dr.Kroese F.G.M., prof. dr.Strijkstra A.M., dr.Rijksuniversiteit Groningen (RUG)2013hibernation acute organ injury immunological
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacologyBrake LHM teBurger D.M., prof. dr.Russel F.G.M., prof. dr.Aarnoutse R.E., dr.Koenderink JB, dr. ir.Radboud Universiteit (RU)2016Tuberculosis; Clinical pharmacology;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgeryBrill M.J.E., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Thermopharmacology of anticonvulsive treatment after perinatal asphyxiaBroek M.P.H. van den, PhDEgberts A.C.G., prof. dr.Rademaker C.M.A., dr.Universiteit Utrecht (UU)2013PK-PD modelling; Newborns; Thermopharmacology; Convulsions;
Unravelling the link between diabetes, insulin treatment and breast cancerBronsveld H.K., PhDBoer A. de, prof. dr.Bruin M.L. de, prof. dr.Schmidt M.K., dr. ir.Universiteit Utrecht (UU)2017Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment;
The road to tailor made azole antifungal therapyBrüggemann R.J.M., PhDBurger D.M., prof. dr.Verweij P.E., prof. dr.Blijlevens N.M.A., dr.Radboud Universiteit (RU)2011Antifungal; clinical pharmacology
Cardiac aldosterone: origin and effectsChai W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Neurovascular pharmacology of prospective antimigraine drugsChan K.Y., PhDDanser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Migraine; Neurovascular pharmacology;
Exposure to antiretroviral agents in hiv-infected pregnant women: not too much-not too littleColbers EPH, dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2015HIV; antiretroviral agents; clinical pharmacology; drug drug interactions
New insights into the role of breast cancer resistance protein in endocrine and metabolic processesDankers A.C.A., PhDRussel F.G.M., prof. dr.Sweep C.G.J., prof. dr.Masereeuw R., prof. dr.Radboud Universiteit (RU)2014Cancer; Breast cancer;
Paving ways for personalizing drug therapy during pregnancyDaud N.A.A., PhDWilffert B, prof. dr.Kammen-Bergman J.E.H. van, dr.Rijksuniversiteit Groningen (RUG)2017Personalized medicine; Drug therapy; Pregnancy;
Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in childrenDe Cock R.F.W., PhDKnibbe C.A.J., prof. dr.Danhof M., prof. dr.Allegaert K., prof. dr.Universiteit Leiden (UL)2014Pediatrics; Population PK; Aminoglycosides; Propylene glycol; GFR; Renal function; Antibiotics; Glomerular filtration; Developmental changes; Pharmacokinetics; Newborns;
Treatment optimization of fluoropyrimidines as single agent and in combination therapyDeenen M.J., PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Cats A., dr.Universiteit Utrecht (UU)2011Pharmacogenetics; Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Dihydropyrimidine dehydrogenase; DPD-deficiency;
The influence of morbid obesity on the pharmacokinetics and pharmacodynamics of drugs in adolescents and adults : focus on propofol and nadroparinDiepstraten J., PhDKnibbe C.A.J., prof. dr.Vinks A.A., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2013Drug dosing; Low-molecular-weight heparines; Nadroparin; Obesity; Pharmacodynamics; Pharmacokinetics; Propofol;
Exploring the role of glucagon in glucose homeostasisDongen M.G.J. van, PhDCohen A.F., prof. dr.Romijn J.A., prof drBurggraaf J., prof. dr.Universiteit Leiden (UL)2015Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
Unintended effects of anti-hyperglycaemic drugs studied in population-based cohortsDriessen J.H.M., PhDBergh J.P.W. van den, prof. dr.Vries F. de, dr.Onzenoort H.A.W. van, PhDUniversiteit Maastricht (UM)2017Hyperglycaemic drugs; Population-based;
Vascular adaptation to pregnancy and relaxinDrongelen J. van, PhDSmits P., prof. dr.Lotgering F.K., prof. dr.Radboud Universiteit (RU)2014
The role of endogenous H2S production during hybernation and forced hypothermia: towards safe cooling and rewarming in clinical practiceDugbartey G.J., PhDHenning R.H., prof. dr.Bouma H.R., PhDRijksuniversiteit Groningen (RUG)2015
Vascular aging from DNA damage to protectionĎurik M., PhDDanser A.H.J., prof. dr.Roks A.J.M., dr.Erasmus Universiteit Rotterdam (EUR)2012Cardiovascular disease; Pharmacology;
Tetrahydrocannabinol in the treatment of neuropsychiatric symptoms in dementiaElsen G. van den, PhDOlde Rikkert M., prof. dr.Verkes R., prof. dr.Marck M. van der, dr. ir.Kramers C., dr.Radboud Universiteit (RU)2016THC; geriatric medicine; pain; Dementia;
Pharmacokinetics and optimal exposure of antifungal drugs in critically ill patientsElst K.C.M. van der, PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015
Unraveling the complexities of the renin-angiotensin system: from ACE to renin inhibitionEsch J.H.M. van, dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2008Cardiovascular disease; Pharmacology; Renin-angiotensin system;
Pediatric type 1 and 2 diabetes mellitus : epidemiology, comorbidities, and medication utilizationFazeli Farsani S., PhDBoer A. de, prof. dr.Knibbe C.A.J., prof. dr.Vorst M.M.J. van der, dr.Mantel-Teeuwisse A.K., dr.Universiteit Utrecht (UU)2015Adolescents; Children; Comorbidities; Epidemiology; Medication use; Diabetes mellitus; UIPS;
Drug effects on the risk and prognosis of community-acquired pneumoniaGarde E.M.W. van de, dr.Leufkens H.G.M., prof. dr.Bosch J.M.M. van den, prof. dr.Souverein P.C., dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2007Pneumonia; Adults; Clinical outcomes; Prevention;
Optimizing cancer therapy. A focus on molecular imagingGaykema S.B.M., PhDVries E.G.E. de, prof. dr.Lub-de Hooge M.N., dr.Rijksuniversiteit Groningen (RUG)2014
Clinical pharmacology of genotype-directed anticancer therapy - Towards rational combination strategiesGeel R.M.J.M. van, PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Huitema A.D.R., prof. dr.Cats A., dr.Universiteit Utrecht (UU)2016Cancer; Genetics; BRAF; Colorectal cancer; Combination therapy; p53-deficient ovarian cancer; AZD1775; Treatment individualization;
The more complex renin-angiotensin system: new insights into an old systemGembardt F., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Renin-angiotensin system;
Integrated pharmaceutical care: cooperation between pharmacist, general practioner, and patient and the development of a pharmaceutical care planGeurts M.M.E., PhDGier J.J. de, prof. dr.Brouwers J.R.B.J., prof. dr.Graeff P.A. de, prof. dr.Rijksuniversiteit Groningen (RUG)2015
The role of efflux and influx transporters in the disposition of digitalis-like compoundsGozalpour E., PhDRussel F.G.M., prof. dr.Radboud Universiteit (RU)2015
Towards better fall prevention - examining the interplay between factors that influence gait in older patientsGroot M.H. de, PhDBeijnen J.H., prof. dr.Lamoth C.J.C., dr.Universiteit Utrecht (UU)2017Falls; Gait analysis; Accelerometry; Frailty; Osteoporosis; Maturation; Medication use; Medication use; Geriatrics; Older patients;
Acute and chronic pain after cardiac surgeryGulik L. van, PhDKnibbe C.A.J., prof. dr.Tibboel D., prof. dr.Bruins P., dr.Universiteit Leiden (UL)2014Acute pain; Intensive Care Unit; Chronic pain; Cardiac surgery; Pain management;
Vascular pharmacology of migraine and preeclampsia: Problems of the fair sexGupta S., dr.Saxena P.R., prof. dr.Danser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2006Cardiovascular disease; Pharmacology;
The role of pharmacogenetics in osteosarcomaHagleitner M.M., PhDHoogerbrugge P.M., prof. dr.Guchelaar H.J., prof. dr.Loo D.M.W.M. te, dr.Coenen M.J.H., dr.Radboud Universiteit (RU)2015Cancer; Osteosarcoma; Pharmacogenetics; Genetics; Chemotherapy;
End-organ damage in diabetes: exploring innovative targets and therapiesHamidi M., PhDHenning R.H., prof. dr.Buikema J.H., dr.Deelman L.E., dr.Rijksuniversiteit Groningen (RUG)2015Diabetes mellitus;
Cognition in Huntington's disease : the influence of motor behaviour and time Hart E.P. 't, PhDRoos R.A.C., prof. dr.Universiteit Leiden (UL)2013Huntington's disease; Cognition; Movement disorder; Executive functioning; Memory; P300; Motor behaviour
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