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Displaying 1-50 of 199 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Rational prescribing in Europe: are future doctors well prepared?Brinkman D.J., PhDAgtmael M.A. van, prof. dr.Richir M.C., MD PhDTichelaar J., dr.Vrije Universiteit Amsterdam (VU)2018Clinical pharmacology; Pharmacotherapy; Prescribing;
Learning in a student-run clinic: a new concept to improve medical education in pharmacotherapySchutte T., PhDAgtmael M.A. van, prof. dr.Richir M.C., MD PhDTichelaar J., dr.Vrije Universiteit Amsterdam (VU)2018Pharmacotherapy education; Student-run clinic; Medical education; Workplace learning; Undergraduate education;
Pharmacological approaches to optimize TB treatmentZuur M.A.Alffenaar J.W.C., dr.Werf T.S. van der, prof. dr.Rijksuniversiteit Groningen (RUG)2018Optimize; Tuberculosis; Treatment;
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studiesNijenhuis C.M., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Rosing H., dr.Universiteit Utrecht (UU)2016
Towards better fall prevention - examining the interplay between factors that influence gait in older patientsGroot M.H. de, PhDBeijnen J.H., prof. dr.Lamoth C.J.C., dr.Universiteit Utrecht (UU)2017Falls; Gait analysis; Accelerometry; Frailty; Osteoporosis; Maturation; Medication use; Medication use; Geriatrics; Older patients;
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasisKip A.E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Dorlo T.P.C., dr.Universiteit Utrecht (UU)2017Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin;
Solid dispersions in oncology: a solution to solubility-limited oral drug absorptionSawicki E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2017Solid dispersions; Pharmacokinetics; Spray drying; Freeze drying; Docetaxel; Paclitaxel; Elacridar;
Unintended effects of anti-hyperglycaemic drugs studied in population-based cohortsDriessen J.H.M., PhDBergh J.P.W. van den, prof. dr.Vries F. de, dr.Onzenoort H.A.W. van, PhDUniversiteit Maastricht (UM)2017Hyperglycaemic drugs; Population-based;
Pharmacogenetics of antihypertensive drug treatmentWieren-de Wijer B.M.A. van, dr.Boer A. de, prof. dr.Stricker B.H.C., prof. dr.Klungel O.H., prof. dr.Maitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2009Pharmacogenetics; Antihypertensive drugs; Study design; Observational studies; UIPS;
Pediatric type 1 and 2 diabetes mellitus : epidemiology, comorbidities, and medication utilizationFazeli Farsani S., PhDBoer A. de, prof. dr.Knibbe C.A.J., prof. dr.Vorst M.M.J. van der, dr.Mantel-Teeuwisse A.K., dr.Universiteit Utrecht (UU)2015Adolescents; Children; Comorbidities; Epidemiology; Medication use; Diabetes mellitus; UIPS;
Performence of statistical methods to control for unmeasured confounding in pharmacoepidemiology : focus on instrumental variable analysisUddin M.J., MD PhDBoer A. de, prof. dr.Roes K.B.C., prof. dr.Groenwold R.H.H., dr.Klungel O.H., prof. dr.Universiteit Utrecht (UU)2014Observational studies; Pharmacoepidemiology; Confounding; Statistical methods; Instrumental variables; SCCS; PERR;
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthmaLeusink M., PhDBoer A. de, prof. dr.Bakker P.I.W. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Onland-Moret N.C., dr.Universiteit Utrecht (UU)2015Pharmacogenomics; Cardiovascular disease; Asthma; Genomics; Genetics; Pharmacology; Statins; Inhaled corticosteroids; Cholesterol;
Methodological approaches to the pharmacogenomics of statinsPeters B.J.M., dr.Boer A. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Klungel O.H., prof. dr.Universiteit Utrecht (UU)2010Methodology; Statins; Pharmacogenomics;
Adverse drug reactions of angiotensin-converting enzyme inhibitors : towards precicion medicineMahmoud Pour S.H., PhDBoer A. de, prof. dr.Asselbergs F.W., prof. dr. MD FESMaitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Adverse drug reaction; Pharmacoepidemiology; Pharmacovigilance; ACE Inhibitors
Risk factors and treatment of paediatric chronic diseases - Type 1 diabetes, asthma and allergyAhmadizar F., PhDBoer A. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Children; Diabetes mellitus; Allergy
Harmonising relative effectiveness assessments of medicines in EuropeKleijnen S., PhDBoer A. de, prof. dr.Leufkens H.G.M., prof. dr.Goettsch W.G., dr.Universiteit Utrecht (UU)2016Medicines; Relative effectiveness; Reimbursement; Harmonisation; Europe; Methods; Health technology assessment (HTA);
Challenges in the clinical development of orphan drugsKreeftmeijer-Vegter A.R., PhDBoer A. de, prof. dr.Vries P.J. de, dr.Universiteit Utrecht (UU)2015Orphan drugs; Clinical development; Paediatric formulation; Pharmacokinetics; Efficacy; Safety; Regulatory;
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safetyNoorsyahdy A.Y., MD PhDBoer A. de, prof. dr.Klungel O.H., prof. dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2017Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics;
Unravelling the link between diabetes, insulin treatment and breast cancerBronsveld H.K., PhDBoer A. de, prof. dr.Bruin M.L. de, prof. dr.Schmidt M.K., dr. ir.Universiteit Utrecht (UU)2017Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment;
Osteoarthritis : association with diabetes mellitus, and treatment-related outcomesNielen J.T.H., PhDBoonen A.E.R.C.H., prof. dr.Dagnelie P.C., prof. dr.Vries F. de, dr.Bemt B.J.F. van den, dr.Universiteit Maastricht (UM)2018Osteoarthritis; Diabetes mellitus; Hip; Knee; Treatment outcomes;
Assessing the impact of gout:validating and understanding outcomesSpaetgens B.P.A., drBoonen A.E.R.C.H., prof. dr.Vries F. de, dr.Universiteit Maastricht (UM)2017
Training physicians in electronic prescribingStiphout F. van, PhDBraak E.W.M.T. ter, prof. dr.Egberts A.C.G., prof. dr.Zwart-van Rijkom J.E.F., dr.Aarts J.E.C.M., dr.Universiteit Utrecht (UU)2016
The road to tailor made azole antifungal therapyBrüggemann R.J.M., PhDBurger D.M., prof. dr.Verweij P.E., prof. dr.Blijlevens N.M.A., dr.Radboud Universiteit (RU)2011Antifungal; clinical pharmacology
Optmizing long-term care for hiv-infected patients in ThailandRamautarsing R.A., PhDBurger D.M., prof. dr.Wit F.W.N.M., dr.Wijgert J.H.H.M. van de, dr.Universiteit van Amsterdam (UvA)2013HIV; clinical pharmacology
Clinical pharmacology of nevirapine in HIV-infected patients in TanzaniaMuro E.P., PhDBurger D.M., prof. dr.Dolmans W.M.V., prof. dr.Radboud Universiteit (RU)2014Clinical pharmacology; HIV; Pharmacokinetics; therapy drug monitoring
Clinical pharmacological studies in tuberculosis patientsSemvua H.H., PhDBurger D.M., prof. dr.Aarnoutse R.E., dr.Boeree M.J., dr.Radboud Universiteit (RU)2014Clinical pharmacology; Pharmacokinetics; Tuberculosis
Introducing Clinical Pharmacology to Hepatitis C TherapyKanter CTMM deBurger D.M., prof. dr.Drenth JPH, prof. dr.Dofferhoff ASM, dr.Radboud Universiteit (RU)2015Hepatitis C; Clinical Pharmacology; Therapeutic drug monitoring; drug drug interactions
Exposure to antiretroviral agents in hiv-infected pregnant women: not too much-not too littleColbers EPH, dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2015HIV; antiretroviral agents; clinical pharmacology; drug drug interactions
Building a clinical pharmacology framework for the safe and effective use of antifungal agentsLempers VJCBurger D.M., prof. dr.Brüggemann R.J.M., PhDAarnoutse R.E., dr.Radboud Universiteit (RU)2016Antifungal drugs; Clinical pharmacology;
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacologyBrake LHM teBurger D.M., prof. dr.Russel F.G.M., prof. dr.Aarnoutse R.E., dr.Koenderink JB, dr. ir.Radboud Universiteit (RU)2016Tuberculosis; Clinical pharmacology;
Making things easier: how to improve antiviral drug treatment for childrenBastiaans D.E.T., dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2016Clinical pharmacology; Antiviral drug treatment;
Minimally invasive methodology for pharmacological research involving childrenKlein R.H., PhDCohen A.F., prof. dr.Burggraaf J., prof. dr.Sukhai R.N., dr.Universiteit Leiden (UL)2013Pediatrics; Clinical pharmacology; ADHD; Pharmacokinetics; Growth hormone deficiency; Pharmacodynamics; Point of care technology;
Non-invasive monitoring of pharmacokinetics and pharmacodynamics for pharmacological drug profiling in children and adolescentsSchrier L., PhDCohen A.F., prof. dr.Gerven J.M.A. van, prof. dr.Sukhai R.N., dr.Universiteit Leiden (UL)2015Non-invasive monitoring; Pharmacokinetics; Pharmacodynamics; Pharmacological drug profiling; Children; Adolescents;
Exploring the role of glucagon in glucose homeostasisDongen M.G.J. van, PhDCohen A.F., prof. dr.Romijn J.A., prof drBurggraaf J., prof. dr.Universiteit Leiden (UL)2015Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
Don't be afraid! Population PK-PD modeling as the basis for individualized dosing in children and critically illPeeters M.Y.M., dr.Danhof M., prof. dr.Tibboel D., prof. dr.Knibbe C.A.J., prof. dr.Universiteit Leiden (UL)2007Pharmacokinetics; Pharmacodynamics; Children; Sedation; Critically ill; Intensive care; NONMEM; Propofol; Midazolam;
Pharmacokinetics, pharmacodynamics and safety of different propofol formulationsKnibbe C.A.J., prof. dr.Danhof M., prof. dr.Aarts L.P.H.J., prof. dr.Kuks P.F.M., dr.Universiteit Leiden (UL)2002Pharmacokinetics; Pharmacodynamics; Propofol;
Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetics Strougo A., PhDDanhof M., prof. dr.Freijer J., dr.Yassen A., dr.Universiteit Leiden (UL)2015Special-population; Model-based; PK-model; Pediatrics; Children; Hepatic and renal impairment; Semi-physiological; Population approach; PBPK;
From data to models : reducing uncertainty in benefit risk assessment : application to chronic iron overload in childrenBellanti F., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2015Benefit-risk assessment; Pediatrics; Iron chelations; PK-PD modelling; Modelling-&-simulations; Multi-criteria-decision-analysis; Iron-overload; Deferiprone; Deferoxamine;
Adherence to antiretroviral combination therapy in children : what a difference half a day makes...Piana C., PhDDanhof M., prof. dr.Della Pasqua O.E., dr.Universiteit Leiden (UL)2013Pediatrics; Antiretroviral combination therapy; Compliance; Antiretroviral drugs; Pediatric populations; Drug combinations; Model-based; Covariate analysis; Predictive pharmacokinetic models; Clinical trial simulations; Adherence; Forgiveness of non-adherence;
Population pharmacokinetics of antibiotics to prevent group B streptococcal disease: from mother to neonateMuller A.E., dr.Danhof M., prof. dr.Steegers E.A.P., prof. dr.Dörr P.J., prof. dr.Mouton J.W., prof. dr.Universiteit Leiden (UL)2009Population PK; Antibiotics; Group B streptococcal infections; Pregnant women; Newborns; GBS (Group B streptococcus);
Angiotensin II-induced vasodilation: role of bradykinin, NO and endothelium-derived hyperpolarizing factorsBatenburg W.W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Cardiac aldosterone: origin and effectsChai W., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2005Cardiovascular disease; Pharmacology;
Unraveling the complexities of the renin-angiotensin system: from ACE to renin inhibitionEsch J.H.M. van, dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2008Cardiovascular disease; Pharmacology; Renin-angiotensin system;
(Pro)renin revisited: new insights from studies in mast cellsKrop M., dr.Danser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2009Cardiovascular disease; Pharmacology; Prorenin;
Natriuretic peptides, diagnostics and prognostic biomarkersRutte J.H.W., dr.Danser A.H.J., prof. dr.Meiracker A.H. van den, dr.Erasmus Universiteit Rotterdam (EUR)2010Antihypertensive drugs; Pharmacology; Kidney; Natriuretic peptides; Renine-angiotensine system;
Neurovascular pharmacology of prospective antimigraine drugsChan K.Y., PhDDanser A.H.J., prof. dr.Maassen van den Brink A., dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Migraine; Neurovascular pharmacology;
Aortic pathology and the role of the renin-angiotensin systemMolzer E., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Cardiovascular disease; Renin-angiotensin system;
The more complex renin-angiotensin system: new insights into an old systemGembardt F., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Pharmacology; Renin-angiotensin system;
Cardiovascular, renal and thyroid toxicity during angiogenesis inhibition: a translational approachKappers M.H.W., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2011Cancer; Pharmacology; Antihypertensive drugs;
Red wine polyphenols and vascular functionBotden I.P.G., PhDDanser A.H.J., prof. dr.Sijbrands E.J.G., prof. dr.Langendonk J.G., dr.Erasmus Universiteit Rotterdam (EUR)2012Antihypertensive drugs; Cardiovascular disease; Pharmacology;
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