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Displaying 51-100 of 209 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Drug-related problems: risk factors and the role of clinical pharmacistsZaal R.J., PhDVulto A.G., prof. dr.Haaijer-Ruskamp F.M., prof. dr.Bemt P.M.L.A. van den, dr.Erasmus Universiteit Rotterdam (EUR)2016Drug-related problems; Risk factors;
Integrating biomarkers to predict renal and cardiovascular drug efficacy: PRE score applications from drug registration to personalized medicineSchievink B.H., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Rijksuniversiteit Groningen (RUG)2016PRE score; Risk markers; Chronic kidney disease; Personalized medicine;
The association between albuminuria and long-term renal risk; how to improve the precision of drug effect estimatesKröpelin T.F., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Rijksuniversiteit Groningen (RUG)2016Kidney; Diabetic kidney disease; Drug efficacy;
Clinical pharmacology and therapeutic drug monitoring of first-line anti-tuberculosis drugsSturkenboom M.G.G., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis; Therapeutic drug monitoring;
Experimental focal cerebral ischemia: optimalisation of models and therapeutic interventionsShanbhag N.C., PhDHenning R.H., prof. dr.Schilling L., prof. dr.Rijksuniversiteit Groningen (RUG)2016Cerebral ischemia;
Adverse drug reactions of angiotensin-converting enzyme inhibitors : towards precicion medicineMahmoud Pour S.H., PhDBoer A. de, prof. dr.Asselbergs F.W., prof. dr. MD FESMaitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Adverse drug reaction; Pharmacoepidemiology; Pharmacovigilance; ACE Inhibitors
Tetrahydrocannabinol in the treatment of neuropsychiatric symptoms in dementiaElsen G. van den, PhDOlde Rikkert M., prof. dr.Verkes R., prof. dr.Marck M. van der, dr. ir.Kramers C., dr.Radboud Universiteit (RU)2016THC; geriatric medicine; pain; Dementia;
Methods for improving the safety of fluoropyrimidine anticancer drugsJacobs B.A.W., PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2016Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Thymidylate synthase; Safety; Phenotyping; Circadian rhythm;
Risk factors and treatment of paediatric chronic diseases - Type 1 diabetes, asthma and allergyAhmadizar F., PhDBoer A. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Children; Diabetes mellitus; Allergy
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studiesNijenhuis C.M., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Rosing H., dr.Universiteit Utrecht (UU)2016
Medication Optimization; exploring the use of a clinical decision support systemWit H.A.J.M. de, PhDSchols J.M.G.A., prof. dr.Kuy P.H.M. van der, dr.Janknegt R., PharmD PhDUniversiteit Maastricht (UM)2016Clinical pharmacology; Clinical rules; CDSS
Building a clinical pharmacology framework for the safe and effective use of antifungal agentsLempers VJCBurger D.M., prof. dr.Brüggemann R.J.M., PhDAarnoutse R.E., dr.Radboud Universiteit (RU)2016Antifungal drugs; Clinical pharmacology;
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacologyBrake LHM teBurger D.M., prof. dr.Russel F.G.M., prof. dr.Aarnoutse R.E., dr.Koenderink JB, dr. ir.Radboud Universiteit (RU)2016Tuberculosis; Clinical pharmacology;
Making things easier: how to improve antiviral drug treatment for childrenBastiaans D.E.T., dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2016Clinical pharmacology; Antiviral drug treatment;
Diagnosis and treatment of obese children with insulin resistanceAa M.P. van der, PhDKnibbe C.A.J., prof. dr.Boer A. de, prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2016Obesity; Children; Insulin resistance; Metformin;
The impact of obesity on the pharmacokinetics of drugs in adolescents and adultsRongen A. van, PhDKnibbe C.A.J., prof. dr.Anker J.N. van den, prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Pharmacokinetics; Obese adolescents; Midazolam; Acetaminophen; Medication use; Medication use; Metformin;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgeryBrill M.J.E., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Revisiting co-trimoxazole for the treatment of tuberculosisAlsaad N.S.I., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis;
Making better prescribers during a context-based pharmacotherapy learning programmeTichelaar J., dr.Vries Th.P.G.M. de, prof. MD, PhDRichir M.C., MD PhDVrije Universiteit Amsterdam (VU)2016pharmacotherapy; pharmacotherapy education; context based learning; clinical pharmacology; prescribing
Harmonising relative effectiveness assessments of medicines in EuropeKleijnen S., PhDBoer A. de, prof. dr.Leufkens H.G.M., prof. dr.Goettsch W.G., dr.Universiteit Utrecht (UU)2016Medicines; Relative effectiveness; Reimbursement; Harmonisation; Europe; Methods; Health technology assessment (HTA);
Optimizing treatment with psychotropic agents through precision drug therapy: It is not about the meanBerm E.J.J., PhDWilffert B, prof. dr.Hak E., prof. dr.Maring J.G., dr.Rijksuniversiteit Groningen (RUG)2016Drug therapy; Psychotropic agents; Treatment individualization; Precision medicine;
The Renin-Angiotensin System in Hypertension and Diabetes: From Man to Rodent and BackRoksnoer L.C.W.Danser A.H.J., prof. dr.Zietse R., prof.dr.Hoorn E.J., dr.Erasmus Universiteit Rotterdam (EUR)2016Renin-angiotensin system; Renal function; Hypertension; Diabetic kidney disease;
Renin-angiotensin system and genetic factors in aneurysms: a translational approachRiet L. te, PhDDanser A.H.J., prof. dr.Verhagen H.J.M., prof. dr.Essers J., dr.Rouwet E.V., dr.Erasmus Universiteit Rotterdam (EUR)2016Renin-angiotensin system; Genetics; Aneurysm
Hypertension and renal toxicity during angiogenesis inhibition: Salt dependency and treatment optionsLankhorst S.Danser A.H.J., prof. dr.Meiracker A.H. van den, dr.Kappers M.H.W., PhDErasmus Universiteit Rotterdam (EUR)2016Hypertension; Renal function; Treatment options
Training physicians in electronic prescribingStiphout F. van, PhDBraak E.W.M.T. ter, prof. dr.Egberts A.C.G., prof. dr.Zwart-van Rijkom J.E.F., dr.Aarts J.E.C.M., dr.Universiteit Utrecht (UU)2016
Physical causes of dosing errors in patients receiving multi-infusion therapySnijder R.A., PhDEgberts A.C.G., prof. dr.Timmerman A.M.D.E., dr. ir.Konings M.K., dr.Universiteit Utrecht (UU)2016Infusion; Multi-infusion; Patient safety; Fluid mechanics; Physics; Modeling errors; Adverse events;
Assessing long-term and rare adverse effects of medicinesDuijnhoven R.G., PhDBoer A. de, prof. dr.Hoes A.W., prof. dr.Bruin M.L. de, prof. dr.Straus S.M.J.M., dr.Universiteit Utrecht (UU)2016Adverse effects; Case-control studies; Clinical trials; Cohort studies; Long-term consequences; Medicines; Regulatory;
Benefits and risks for the individual : anticoagulation for patients with atrial fibrillationHam H.A. van den, PhDLeufkens H.G.M., prof. dr.Klungel O.H., prof. dr.Staa T.J. van, prof. dr.Universiteit Utrecht (UU)2016Benefit-risk balance; Atrial fibrillation; Oral anticoagulants; Observational studies; Individuals;
Patients at increased fracture risk : identification and pharmacological treatmentKlop C., PhDLeufkens H.G.M., prof. dr.Bijlsma J.W.J., prof. dr.Vries F. de, dr.Welsing P.M.J., dr.Universiteit Utrecht (UU)2016Fragility fracture; Hip fracture; Hip; Osteoporosis; Biphosphonate; Absolute risk prediction; FRAX;
Pediatric type 1 and 2 diabetes mellitus : epidemiology, comorbidities, and medication utilizationFazeli Farsani S., PhDBoer A. de, prof. dr.Knibbe C.A.J., prof. dr.Vorst M.M.J. van der, dr.Mantel-Teeuwisse A.K., dr.Universiteit Utrecht (UU)2015Adolescents; Children; Comorbidities; Epidemiology; Medication use; Diabetes mellitus; UIPS;
The role of pharmacogenetics in osteosarcomaHagleitner M.M., PhDHoogerbrugge P.M., prof. dr.Guchelaar H.J., prof. dr.Loo D.M.W.M. te, dr.Coenen M.J.H., dr.Radboud Universiteit (RU)2015Cancer; Osteosarcoma; Pharmacogenetics; Genetics; Chemotherapy;
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthmaLeusink M., PhDBoer A. de, prof. dr.Bakker P.I.W. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Onland-Moret N.C., dr.Universiteit Utrecht (UU)2015Pharmacogenomics; Cardiovascular disease; Asthma; Genomics; Genetics; Pharmacology; Statins; Inhaled corticosteroids; Cholesterol;
The alternative renin-angiotensin system: exploration of its therapeutic potentialSevá Pessôa B., PhDDanser A.H.J., prof. dr.Roks A.J.M., dr.Erasmus Universiteit Rotterdam (EUR)2015Pharmacology; Cardiovascular disease; Renin-angiotensin system;
Preeclampsia, the renin-angiotensin-aldosterone system and beyondVerdonk K., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2015Pre-eclampsia; Antihypertensive drugs; Pharmacology; Primary care; Renin-angiotensin system;
Integrated pharmaceutical care: cooperation between pharmacist, general practioner, and patient and the development of a pharmaceutical care planGeurts M.M.E., PhDGier J.J. de, prof. dr.Brouwers J.R.B.J., prof. dr.Graeff P.A. de, prof. dr.Rijksuniversiteit Groningen (RUG)2015
Non-invasive monitoring of pharmacokinetics and pharmacodynamics for pharmacological drug profiling in children and adolescentsSchrier L., PhDCohen A.F., prof. dr.Gerven J.M.A. van, prof. dr.Sukhai R.N., dr.Universiteit Leiden (UL)2015Non-invasive monitoring; Pharmacokinetics; Pharmacodynamics; Pharmacological drug profiling; Children; Adolescents;
Exploring the role of glucagon in glucose homeostasisDongen M.G.J. van, PhDCohen A.F., prof. dr.Romijn J.A., prof drBurggraaf J., prof. dr.Universiteit Leiden (UL)2015Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
The role of efflux and influx transporters in the disposition of digitalis-like compoundsGozalpour E., PhDRussel F.G.M., prof. dr.Radboud Universiteit (RU)2015
The many faces of Na+, K+-ATPase: understanding the role of human isoforms in health and diseaseWeigand K.M., PhDRussel F.G.M., prof. dr.Radboud Universiteit (RU)2015
Linezolid in multidrug-resistant tuberculosisBolhuis M.S., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015Tuberculosis; Linezolid;
Patient perspectives in the benefit-risk evaluation of drugsVries S.T. de, PhDDenig P., prof. dr.Haaijer-Ruskamp F.M., prof. dr.Zeeuw D. de, prof. dr.Rijksuniversiteit Groningen (RUG)2015
Pharmacokinetics and optimal exposure of antifungal drugs in critically ill patientsElst K.C.M. van der, PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015
Preclinical targeting of the tumor microenvironment. Possibilities and consequencesArjaans M., PhDVries E.G.E. de, prof. dr.Schröder C.P., dr.Timmer-Bosscha H., dr.Rijksuniversiteit Groningen (RUG)2015
Pharmacokinetics of antifungal drugs in severely ill patientsWanrooy M.J.P. van, PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015Antifungal drugs; Pharmacokinetics;
The role of endogenous H2S production during hybernation and forced hypothermia: towards safe cooling and rewarming in clinical practiceDugbartey G.J., PhDHenning R.H., prof. dr.Bouma H.R., PhDRijksuniversiteit Groningen (RUG)2015
The influence of the sample matrix on LC-MS/MS method development and analytical performanceKoster R.A., PhDUges D.R.A., prof. dr.Kosterink J.G.W., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015
End-organ damage in diabetes: exploring innovative targets and therapiesHamidi M., PhDHenning R.H., prof. dr.Buikema J.H., dr.Deelman L.E., dr.Rijksuniversiteit Groningen (RUG)2015Diabetes mellitus;
Novel biomarker panels in diabetic kidney disease: predicting disease progression and response to therapy, and monitoring drug effectPena M.J., PhDZeeuw D. de, prof. dr.Lambers Heerspink H.J., prof. dr.Rijksuniversiteit Groningen (RUG)2015Biomarkers; Diabetes mellitus; Kidney;
Clinical risk management of drug-related hospital admissions: strategies for their identification, reduction and monitoringWarlé-van Herwaarden M., PhDSmet P.A.G.M. de, prof. dr.Sturkenboom M.C.J.M., prof. dr.Kramers C., dr.Herings R.M.C., dr.Radboud Universiteit (RU)2015Guideline adherence; medication safety; laboratory monitoring
COMPARE: Care in Oncolytic Medication surveillance:Pharmacovigilance, Acceptability, Risks and EventsOijen B.P.C. van, dr.Schouten H.C., prof. dr.Kuy P.H.M. van der, dr.Janknegt R., PharmD PhDUniversiteit Maastricht (UM)2015Chemotherapy; Clinical pharmacology; Pharmaceutical care;
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