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Displaying 1-50 of 145 results.
TitelPromovendusPromotor 1Promotor 2Copromotor 1Copromotor 2UniversiteitPromotiejaarTrefwoorden
Pharmaceutical development, preclinical research and clinical application of the bone-targeting therapeutic radiopharmaceutical rhenium-188-HEDPLange R., PhDHendrikse N.H., prof. dr.Heine R. ter, dr.Bloemendal H.J., dr.Vrije Universiteit Amsterdam (VU)2017Radiopharmaceutics; Pharmaceutical development; Rhenium;
Unintended effects of anti-hyperglycaemic drugs studied in population-based cohortsDriessen J.H.M., PhDBergh J.P.W. van den, prof. dr.Vries F. de, dr.Onzenoort H.A.W. van, PhDUniversiteit Maastricht (UM)2017Hyperglycaemic drugs; Population-based;
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantationAdmiraal R., PhDKnibbe C.A.J., prof. dr.Boelens J.J., dr.Bredius R.G.M., dr.Universiteit Leiden (UL)2017ATG; Population PK; Stem cell transplantation; Immune reconstitution; Serotherapy;
ColoPulse tablets in inflammatory bowel disease: formulation, potential application and evaluationMaurer J.M., PhDKosterink J.G.W., prof. dr.Frijlink H.W., prof. dr.Woerdenbag H.J., dr.Rijksuniversiteit Groningen (RUG)2017ColoPulse tablets; Inflammatory bowel disease;
Exploring optimal pharmacotherapy after bariatic surgery: where two worlds meetYska J.P., PhDRoon E.N. van, prof. dr.Wilffert B, prof. dr.Rijksuniversiteit Groningen (RUG)2017Optimal pharmacotherapy; Bariatric surgery;
Techniques to improve neurological outcome after cardiac surgeryKok W.F., PhDHenning R.H., prof. dr.Absalom A.R., prof. dr.Scheeren T.W.L., prof. dr.Rijksuniversiteit Groningen (RUG)2017Cardiac surgery; Clinical pharmacology; Neurological outcome;
Towards better fall prevention - examining the interplay between factors that influence gait in older patientsGroot M.H. de, PhDBeijnen J.H., prof. dr.Lamoth C.J.C., dr.Universiteit Utrecht (UU)2017Falls; Gait analysis; Accelerometry; Frailty; Osteoporosis; Maturation; Medication use; Medication use; Geriatrics; Older patients;
Clinical pharmacology and bioanalysis of antileishmanial drugs : Towards improved treatment strategies for leishmaniasisKip A.E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Dorlo T.P.C., dr.Universiteit Utrecht (UU)2017Leishmaniasis; Clinical pharmacology; Bioanalysis; Pharmacokinetics; Pharmacodynamics; Miltefosine; Amphotericin B; Neopterin;
Antiplatelet drugs for secondary prevention of cardiovascular diseases : drug utilization, effectiveness, and safetyNoorsyahdy A.Y., MD PhDBoer A. de, prof. dr.Klungel O.H., prof. dr.Deneer V.H.M., dr.Universiteit Utrecht (UU)2017Antiplatelet drugs; Secondary prevention; Myocardial infarction; Ischemic stroke; Cardiac arrest; Pharmacogenetics;
Solid dispersions in oncology: a solution to solubility-limited oral drug absorptionSawicki E., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2017Solid dispersions; Pharmacokinetics; Spray drying; Freeze drying; Docetaxel; Paclitaxel; Elacridar;
Paving ways for personalizing drug therapy during pregnancyDaud N.A.A., PhDWilffert B, prof. dr.Kammen-Bergman J.E.H. van, dr.Rijksuniversiteit Groningen (RUG)2017Personalized medicine; Drug therapy; Pregnancy;
Multimodality ImAging of Cardiovascular Dysfunction: Risk factors, diagnostics and treatment optionsThiel B.S. van, PhDKanaar R., prof. dr.Danser A.H.J., prof. dr.Essers J., dr.Pluijm I. van der, dr.Erasmus Universiteit Rotterdam (EUR)2017Cardiovascular disease; Imaging; Aging; Risk factors; Diagnostics; Treatment options
Unravelling the link between diabetes, insulin treatment and breast cancerBronsveld H.K., PhDBoer A. de, prof. dr.Bruin M.L. de, prof. dr.Schmidt M.K., dr. ir.Universiteit Utrecht (UU)2017Breast cancer; Risk factors; Diabetes mellitus; Insulin growth factor; Diabetes treatment;
Clinical pharmacology of genotype-directed anticancer therapy - Towards rational combination strategiesGeel R.M.J.M. van, PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Huitema A.D.R., prof. dr.Cats A., dr.Universiteit Utrecht (UU)2016Cancer; Genetics; BRAF; Colorectal cancer; Combination therapy; p53-deficient ovarian cancer; AZD1775; Treatment individualization;
Implications of the cardiomyocyte stress response on protein homeostasis in atrial fibrillationWiersma M., PhDHenning R.H., prof. dr.Brundel B.J.J.M., dr.Rijksuniversiteit Groningen (RUG)2016Atrial fibrillation;
Statin treatment in type 2 diabetes patiëntsVries F.M. de, PhDHak E., prof. dr.Denig P., prof. dr.Postma M.J., prof. dr.Rijksuniversiteit Groningen (RUG)2016Statins; Diabetes mellitus;
Clinical pharmacology and therapeutic drug monitoring of first-line anti-tuberculosis drugsSturkenboom M.G.G., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis; Therapeutic drug monitoring;
Experimental focal cerebral ischemia: optimalisation of models and therapeutic interventionsShanbhag N.C., PhDHenning R.H., prof. dr.Schilling L., prof. dr.Rijksuniversiteit Groningen (RUG)2016Cerebral ischemia;
Adverse drug reactions of angiotensin-converting enzyme inhibitors : towards precicion medicineMahmoud Pour S.H., PhDBoer A. de, prof. dr.Asselbergs F.W., MD PhD FESMaitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Adverse drug reaction; Pharmacoepidemiology; Pharmacovigilance; ACE Inhibitors
Tetrahydrocannabinol in the treatment of neuropsychiatric symptoms in dementiaElsen G. van den, PhDOlde Rikkert M., prof. dr.Verkes R., prof. dr.Marck M. van der, dr. ir.Kramers C., dr.Radboud Universiteit (RU)2016THC; geriatric medicine; pain; Dementia;
Methods for improving the safety of fluoropyrimidine anticancer drugsJacobs B.A.W., PhDSchellens J.H.M., prof. dr.Beijnen J.H., prof. dr.Nuijen B., dr.Universiteit Utrecht (UU)2016Fluoropyrimidines; Capecitabine; 5-fluorouracil; Dihydropyrimidine dehydrogenase; Thymidylate synthase; Safety; Phenotyping; Circadian rhythm;
Risk factors and treatment of paediatric chronic diseases - Type 1 diabetes, asthma and allergyAhmadizar F., PhDBoer A. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Universiteit Utrecht (UU)2016Children; Diabetes mellitus; Allergy
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studiesNijenhuis C.M., PhDBeijnen J.H., prof. dr.Schellens J.H.M., prof. dr.Rosing H., dr.Universiteit Utrecht (UU)2016
Medication Optimization; exploring the use of a clinical decision support systemWit H.A.J.M. de, PhDSchols J.M.G.A., prof. dr.Kuy P.H.M. van der, dr.Janknegt R., PharmD PhDUniversiteit Maastricht (UM)2016Clinical pharmacology; Clinical rules; CDSS
Building a clinical pharmacology framework for the safe and effective use of antifungal agentsLempers VJCBurger D.M., prof. dr.Brüggemann R.J.M., PhDAarnoutse R.E., dr.Radboud Universiteit (RU)2016Antifungal drugs; Clinical pharmacology;
Translational research in tuberculosis: crossing barriers between molecular and clinical pharmacologyBrake LHM teBurger D.M., prof. dr.Russel F.G.M., prof. dr.Aarnoutse R.E., dr.Koenderink JB, dr. ir.Radboud Universiteit (RU)2016Tuberculosis; Clinical pharmacology;
Making things easier: how to improve antiviral drug treatment for childrenBastiaans D.E.T., dr.Burger D.M., prof. dr.Radboud Universiteit (RU)2016Clinical pharmacology; Antiviral drug treatment;
Diagnosis and treatment of obese children with insulin resistanceAa M.P. van der, PhDKnibbe C.A.J., prof. dr.Boer A. de, prof. dr.Vorst M.M.J. van der, dr.Universiteit Leiden (UL)2016Obesity; Children; Insulin resistance; Metformin;
The impact of obesity on the pharmacokinetics of drugs in adolescents and adultsRongen A. van, PhDKnibbe C.A.J., prof. dr.Anker J.N. van den, prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Pharmacokinetics; Obese adolescents; Midazolam; Acetaminophen; Medication use; Medication use; Metformin;
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgeryBrill M.J.E., PhDKnibbe C.A.J., prof. dr.Dongen H.P.A. van, dr.Ramshorst B. van, dr.Universiteit Leiden (UL)2016Morbid obesity; Cefazolin; Midazolam; Bariatric surgery; Microdialysis; P53-deficient ovarian cancer; PK-PD modelling;
Revisiting co-trimoxazole for the treatment of tuberculosisAlsaad N.S.I., PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2016Tuberculosis;
Harmonising relative effectiveness assessments of medicines in EuropeKleijnen S., PhDBoer A. de, prof. dr.Leufkens H.G.M., prof. dr.Goettsch W.G., dr.Universiteit Utrecht (UU)2016Medicines; Relative effectiveness; Reimbursement; Harmonisation; Europe; Methods; Health technology assessment (HTA);
Optimizing treatment with psychotropic agents through precision drug therapy: It is not about the meanBerm E.J.J., PhDWilffert B, prof. dr.Hak E., prof. dr.Maring J.G., dr.Rijksuniversiteit Groningen (RUG)2016Drug therapy; Psychotropic agents; Treatment individualization; Precision medicine;
The Renin-Angiotensin System in Hypertension and Diabetes: From Man to Rodent and BackRoksnoer L.C.W.Danser A.H.J., prof. dr.Zietse R., prof.dr.Hoorn E.J., dr.Erasmus Universiteit Rotterdam (EUR)2016Renin-angiotensin system; Renal function; Hypertension; Diabetic kidney disease;
Renin-Angiotensin System and Genetic Factors in Aneurysms: A Translational ApproachRiet L te, drDanser A.H.J., prof. dr.Verhagen H.J.M., prof.dr.Essers J., dr.Rouwet E.V., dr.Erasmus Universiteit Rotterdam (EUR)2016Renin-angiotensin system; Genetics; Aneurysm
Hypertension and renal toxicity during angiogenesis inhibition: Salt dependency and treatment optionsLankhorst S.Danser A.H.J., prof. dr.Meiracker A.H. van den, dr.Kappers M.H.W., PhDErasmus Universiteit Rotterdam (EUR)2016Hypertension; Renal function; Treatment options
Pediatric type 1 and 2 diabetes mellitus : epidemiology, comorbidities, and medication utilizationFazeli Farsani S., PhDBoer A. de, prof. dr.Knibbe C.A.J., prof. dr.Vorst M.M.J. van der, dr.Mantel-Teeuwisse A.K., dr.Universiteit Utrecht (UU)2015Adolescents; Children; Comorbidities; Epidemiology; Medication use; Diabetes mellitus; UIPS;
The role of pharmacogenetics in osteosarcomaHagleitner M.M., PhDHoogerbrugge P.M., prof. dr.Guchelaar H.J., prof. dr.Loo D.M.W.M. te, dr.Coenen M.J.H., dr.Radboud Universiteit (RU)2015Cancer; Osteosarcoma; Pharmacogenetics; Genetics; Chemotherapy;
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthmaLeusink M., PhDBoer A. de, prof. dr.Bakker P.I.W. de, prof. dr.Maitland-van der Zee A.H., prof. dr.Onland-Moret N.C., dr.Universiteit Utrecht (UU)2015Pharmacogenomics; Cardiovascular disease; Asthma; Genomics; Genetics; Pharmacology; Statins; Inhaled corticosteroids; Cholesterol;
The alternative renin-angiotensin system: exploration of its therapeutic potentialSevá Pessôa B., PhDDanser A.H.J., prof. dr.Roks A.J.M., dr.Erasmus Universiteit Rotterdam (EUR)2015Pharmacology; Cardiovascular disease; Renin-angiotensin system;
Preeclampsia, the renin-angiotensin-aldosterone system and beyondVerdonk K., PhDDanser A.H.J., prof. dr.Erasmus Universiteit Rotterdam (EUR)2015Pre-eclampsia; Antihypertensive drugs; Pharmacology; Primary care; Renin-angiotensin system;
Integrated pharmaceutical care: cooperation between pharmacist, general practioner, and patient and the development of a pharmaceutical care planGeurts M.M.E., PhDGier J.J. de, prof. dr.Brouwers J.R.B.J., prof. dr.Graeff P.A. de, prof. dr.Rijksuniversiteit Groningen (RUG)2015
Non-invasive monitoring of pharmacokinetics and pharmacodynamics for pharmacological drug profiling in children and adolescentsSchrier L., PhDCohen A.F., prof. dr.Gerven J.M.A. van, prof. dr.Sukhai R.N., dr.Universiteit Leiden (UL)2015Non-invasive monitoring; Pharmacokinetics; Pharmacodynamics; Pharmacological drug profiling; Children; Adolescents;
Exploring the role of glucagon in glucose homeostasisDongen M.G.J. van, PhDCohen A.F., prof. dr.Romijn J.A., prof drBurggraaf J., prof. dr.Universiteit Leiden (UL)2015Glucagon; Diabetes mellitus; Glucose homeostasis; Glucagon challenge; Glucagon receptor antagonist; Insulin
The role of efflux and influx transporters in the disposition of digitalis-like compoundsGozalpour E., PhDRussel F.G.M., prof. dr.Radboud Universiteit (RU)2015
The many faces of Na+, K+-ATPase: understanding the role of human isoforms in health and diseaseWeigand K.M., PhDRussel F.G.M., prof. dr.Radboud Universiteit (RU)2015
Linezolid in multidrug-resistant tuberculosisBolhuis M.S., PhDWerf T.S. van der, prof. dr.Kosterink J.G.W., prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015Tuberculosis; Linezolid;
Patient perspectives in the benefit-risk evaluation of drugsVries S.T. de, PhDDenig P., prof. dr.Haaijer-Ruskamp F.M., prof. dr.Zeeuw D. de, prof. dr.Rijksuniversiteit Groningen (RUG)2015
Pharmacokinetics and optimal exposure of antifungal drugs in critically ill patientsElst K.C.M. van der, PhDKosterink J.G.W., prof. dr.Werf T.S. van der, prof. dr.Uges D.R.A., prof. dr.Alffenaar J.W.C., dr.Rijksuniversiteit Groningen (RUG)2015
Preclinical targeting of the tumor microenvironment. Possibilities and consequencesArjaans M., PhDVries E.G.E. de, prof. dr.Schröder C.P., dr.Timmer-Bosscha H., dr.Rijksuniversiteit Groningen (RUG)2015
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